Penciclovir
(Redirected from Denavir)
Penciclovir is an antiviral medication used to treat herpes simplex virus infections. It is a guanosine analogue and a nucleoside analogue. It is primarily used in the treatment of herpes labialis (cold sores) and herpes zoster (shingles).
Mechanism of Action[edit | edit source]
Penciclovir works by inhibiting the replication of the herpes simplex virus. It is converted into a triphosphate form in the infected cells which inhibits the viral DNA polymerase, thereby preventing the virus from multiplying.
Pharmacokinetics[edit | edit source]
After topical application, penciclovir is absorbed into the skin where it is converted into its active form. It has a half-life of 2 hours and is excreted in the urine.
Side Effects[edit | edit source]
Common side effects of penciclovir include nausea, headache, and rash. In rare cases, it can cause serious side effects such as anaphylaxis and angioedema.
Interactions[edit | edit source]
Penciclovir can interact with other antiviral medications such as acyclovir and ganciclovir. It can also interact with probenecid, a medication used to treat gout.
Contraindications[edit | edit source]
Penciclovir is contraindicated in patients with known hypersensitivity to penciclovir or any of its components.
See Also[edit | edit source]
Penciclovir Resources | |
---|---|
|
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
WikiMD's Wellness Encyclopedia |
Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD