Dengue vaccine
Dengue Vaccine[edit | edit source]
The dengue vaccine is a vaccine used to prevent dengue fever in humans. Dengue fever is a mosquito-borne tropical disease caused by the dengue virus. The vaccine is particularly important in areas where dengue is endemic, as it can significantly reduce the incidence of the disease and its associated complications.
Types of Dengue Vaccines[edit | edit source]
There are several types of dengue vaccines that have been developed or are in development. These include:
- Live attenuated vaccines: These vaccines use a weakened form of the virus to stimulate an immune response without causing the disease.
- Inactivated vaccines: These vaccines use a virus that has been killed, so it cannot cause disease, but can still provoke an immune response.
- Subunit vaccines: These vaccines use only parts of the virus, such as proteins, to stimulate an immune response.
- DNA vaccines: These vaccines use genetically engineered DNA to produce an immune response.
Qdenga Vaccine[edit | edit source]
Qdenga is one of the dengue vaccines that has been developed to combat the disease. It is a live attenuated tetravalent vaccine, meaning it is designed to protect against all four serotypes of the dengue virus. The vaccine is administered in a series of doses and is intended for use in individuals living in or traveling to areas where dengue is common.
Mechanism of Action[edit | edit source]
The dengue vaccine works by stimulating the body's immune system to produce antibodies against the dengue virus. When a vaccinated person is later exposed to the virus, their immune system can recognize and fight the virus more effectively, reducing the severity of the disease or preventing it altogether.
Challenges and Considerations[edit | edit source]
Developing a dengue vaccine is challenging due to the presence of four distinct serotypes of the virus. A vaccine must provide immunity against all four serotypes to be effective. Additionally, there is a risk of antibody-dependent enhancement (ADE), where a person who has been vaccinated or previously infected with one serotype may experience more severe disease if infected with a different serotype.
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