Diacetylnalorphine

From WikiMD's Wellness Encyclopedia

Diacetylnalorphine is a semi-synthetic opioid derived from morphine. It is also known as Paralaudin, and it is a potent analgesic used for the relief of severe pain.

Chemistry[edit | edit source]

Diacetylnalorphine is a morphine derivative where the 3 and 6 hydroxyl groups have been acetylated. The chemical formula of diacetylnalorphine is C21H23NO5. It is a white crystalline powder that is soluble in water.

Pharmacology[edit | edit source]

Diacetylnalorphine acts on the mu opioid receptor in the central nervous system, producing analgesia and sedation. It is more potent than morphine and has a faster onset of action. However, it also has a shorter duration of action, which can lead to a higher risk of dependence and addiction.

Medical Use[edit | edit source]

Diacetylnalorphine is used in the treatment of severe pain, such as that caused by cancer or severe injury. It is usually administered by injection. Due to its high potential for addiction, it is a controlled substance in many countries.

Side Effects[edit | edit source]

Common side effects of diacetylnalorphine include nausea, vomiting, constipation, and drowsiness. More serious side effects can include respiratory depression, dependence, and overdose.

History[edit | edit source]

Diacetylnalorphine was first synthesized in the early 20th century as a potential alternative to morphine. However, it was soon found to have a higher potential for addiction and was largely replaced by other opioids.

See Also[edit | edit source]

Medicine-stub.png
This article is a stub related to medicine. You can help WikiMD by expanding it!


WikiMD
Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD

Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD

WikiMD's Wellness Encyclopedia

Let Food Be Thy Medicine
Medicine Thy Food - Hippocrates

Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.

Contributors: Prab R. Tumpati, MD