Dientamoeba fragilis

Dientamoeba fragilis is a species of single-celled amoeba that is commonly associated with gastrointestinal illness. Despite its classification as an amoeba, it does not possess the typical morphological characteristics of other amoebae, such as pseudopodia for movement.

Taxonomy

Dientamoeba fragilis belongs to the kingdom Protista, phylum Amoebozoa, and class Archamoebae. It is the only species in the genus Dientamoeba.

Morphology

The morphology of D. fragilis is unique among amoebae. It lacks the pseudopodia typically used for movement and instead has a more passive mode of locomotion. The organism is binucleated, meaning it has two nuclei, and it reproduces through binary fission.

Pathogenicity

D. fragilis is a common cause of gastroenteritis, with symptoms including abdominal pain, diarrhea, and weight loss. However, many infected individuals are asymptomatic. The mechanism of pathogenicity is not well understood, but it is thought to involve damage to the intestinal epithelium.

Diagnosis and treatment

Diagnosis of D. fragilis infection is typically made through microscopic examination of stool samples. Treatment usually involves the use of antiprotozoal medications, such as metronidazole.

Epidemiology

D. fragilis is found worldwide, but is more common in developing countries. It is transmitted through the fecal-oral route, often via contaminated food or water.

See also

• Amoebiasis
• Parasitic diseases
• Protozoa