EGJOO

EGJOO (Esophagogastric Junction Outflow Obstruction) is a medical condition characterized by impaired relaxation of the lower esophageal sphincter (LES) and the esophagogastric junction (EGJ) during swallowing. This condition can lead to difficulty in the passage of food from the esophagus into the stomach, causing various symptoms and complications.

Symptoms

Patients with EGJOO may experience a range of symptoms, including:

• Dysphagia (difficulty swallowing)
• Chest pain
• Regurgitation
• Heartburn
• Weight loss

Diagnosis

The diagnosis of EGJOO typically involves several diagnostic tests, including:

• High-resolution manometry (HRM): This test measures the pressure within the esophagus and the function of the LES.
• Barium swallow: An X-ray imaging test that visualizes the esophagus and the flow of barium into the stomach.
• Endoscopy: A procedure that uses a flexible tube with a camera to examine the esophagus and stomach.

Causes

The exact cause of EGJOO is not well understood. However, it is believed to be related to abnormalities in the muscles or nerves of the esophagus and the LES. Potential contributing factors include:

• Achalasia
• Esophageal motility disorders
• Gastroesophageal reflux disease (GERD)
• Esophageal strictures

Treatment

Treatment options for EGJOO may vary depending on the severity of the condition and the underlying cause. Common treatments include:

• Medications: Such as calcium channel blockers or nitrates to relax the LES.
• Botulinum toxin injections: To temporarily relax the LES.
• Pneumatic dilation: A procedure that uses a balloon to stretch the LES.
• Surgical myotomy: A surgical procedure to cut the muscles of the LES.

Prognosis

The prognosis for patients with EGJOO varies. Some patients may respond well to treatment and experience significant symptom relief, while others may have persistent symptoms despite treatment. Regular follow-up with a healthcare provider is essential to manage the condition effectively.

Related Pages

• Achalasia
• Esophageal motility disorders
• Gastroesophageal reflux disease
• Dysphagia
• Endoscopy

Resources

Latest articles - EGJOO

• Most recent articles
• Ongoing trials

Source: Data courtesy of the U.S. National Library of Medicine. Since the data might have changed, please query MeSH on EGJOO for any updates.

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