ERV3

ERV3 or Endogenous Retrovirus 3 is a type of endogenous retrovirus that is found in the genome of humans and other primates. It is one of the many retroviruses that have been incorporated into the genetic material of our ancestors and passed down through generations.

Overview

File:ERV3 structure.png

Structure of ERV3

ERV3 is a unique endogenous retrovirus as it is one of the few that is still capable of producing viral particles. It is located on chromosome 7 and is thought to play a role in placental development and function.

Function

The exact function of ERV3 is not fully understood, but it is believed to play a role in the development and function of the placenta. Some studies have suggested that ERV3 may be involved in the regulation of gene expression in the placenta, and may also play a role in protecting the fetus from other viral infections.

Clinical significance

Alterations in the expression of ERV3 have been associated with several diseases, including schizophrenia, rheumatoid arthritis, and cancer. However, the exact role of ERV3 in these diseases is not yet fully understood and is the subject of ongoing research.

Research

Research into ERV3 and other endogenous retroviruses is a rapidly growing field, with potential implications for our understanding of human evolution, development, and disease.

See also

• Endogenous retrovirus
• Retrovirus
• Human genome
• Gene expression