Eduardo Braun-Menéndez

Argentine physiologist and biologist

Eduardo Braun-Menéndez

Eduardo Braun-Menéndez (1903–1959) was a prominent Argentine physiologist and biologist known for his significant contributions to the understanding of the renin-angiotensin system, a hormone system that regulates blood pressure and fluid balance. His work laid the foundation for modern cardiovascular medicine and has had a lasting impact on the field of physiology.

Early Life and Education

Eduardo Braun-Menéndez was born on January 2, 1903, in Buenos Aires, Argentina. He pursued his medical studies at the University of Buenos Aires, where he developed a keen interest in physiology and biochemistry. His academic excellence earned him a scholarship to further his studies in the United States, where he worked alongside renowned scientists and honed his research skills.

Career and Research

Braun-Menéndez returned to Argentina and joined the Instituto de Biología y Medicina Experimental, where he collaborated with other leading scientists of his time. His most notable work was in the field of cardiovascular physiology, particularly his research on the renin-angiotensin system.

Renin-Angiotensin System

The renin-angiotensin system is crucial for the regulation of blood pressure and electrolyte balance. Braun-Menéndez's research focused on the role of angiotensin, a peptide hormone that causes blood vessels to constrict, leading to an increase in blood pressure. His studies demonstrated the mechanism by which renin, an enzyme secreted by the kidneys, acts on a substrate to produce angiotensin, thus elucidating a key pathway in blood pressure regulation.

Collaboration with Bernardo Houssay

Braun-Menéndez worked closely with Bernardo Houssay, a Nobel laureate, at the Instituto de Biología y Medicina Experimental. Their collaboration was instrumental in advancing the understanding of hormonal regulation of blood pressure and metabolism. Together, they published numerous papers that contributed to the global recognition of Argentine science.

Legacy and Impact

Eduardo Braun-Menéndez's pioneering research has had a profound impact on the field of medicine. The renin-angiotensin system remains a critical target for antihypertensive drugs, and his work continues to influence the development of treatments for hypertension and heart failure.

Death

Braun-Menéndez died tragically in a plane crash on January 15, 1959, at the age of 56. Despite his untimely death, his legacy endures through his contributions to medical science and the many lives saved by treatments developed from his research.

Related Pages

• Renin-angiotensin system
• Bernardo Houssay
• University of Buenos Aires
• Physiology