Elizabeth Hughes Gossett

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Elizabeth Hughes Gossett


Elizabeth Hughes Gossett (August 19, 1907 – April 21, 1981) was one of the first American patients treated with insulin for Type 1 diabetes, and a prominent figure in the history of diabetes treatment. The daughter of Charles Evans Hughes, a U.S. Secretary of State and Chief Justice of the United States, Elizabeth's diagnosis and subsequent treatment with insulin were pivotal moments in medical history, showcasing the life-saving potential of the newly discovered hormone.

Early Life and Diagnosis[edit | edit source]

Elizabeth was born into a prominent family, with her father being a significant figure in American politics and law. In 1919, at the age of 11, she was diagnosed with Type 1 diabetes, a condition that was essentially a death sentence at the time. The standard treatment before the discovery of insulin was a starvation diet, which only temporarily prolonged life. Elizabeth's condition deteriorated rapidly, and her prospects seemed grim.

Treatment with Insulin[edit | edit source]

In 1922, Elizabeth became one of the first patients to receive insulin, a treatment discovered by Frederick Banting and Charles Best. This treatment was experimental at the time, and Elizabeth was treated in Toronto, Canada, by Dr. Banting himself. The insulin treatment was successful, and Elizabeth's health improved dramatically, allowing her to lead a relatively normal life. Her case became a beacon of hope for diabetics worldwide and marked a significant milestone in the treatment of the disease.

Later Life[edit | edit source]

After her recovery, Elizabeth Hughes pursued an education, attending Barnard College and later studying at Columbia University. She maintained her diabetes in relative secrecy, a testament to the stigma associated with the disease at the time. In 1930, she married William T. Gossett, and they had three children. Throughout her life, Elizabeth was an advocate for diabetes research and treatment, though she did so quietly, preferring to keep her personal health issues private.

Elizabeth Hughes Gossett passed away in 1981, having lived nearly 60 years longer than expected, thanks to the advent of insulin therapy. Her life story is not only a personal tale of survival and resilience but also a significant chapter in the history of medicine, highlighting the impact of insulin on the lives of diabetics.

Legacy[edit | edit source]

Elizabeth Hughes Gossett's experience with diabetes and early insulin treatment played a crucial role in demonstrating the efficacy of insulin for diabetes management. Her story is often cited in medical and historical discussions about the disease and its treatment. Moreover, her life underscores the importance of medical innovation and the profound difference it can make in individual lives.


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Contributors: Prab R. Tumpati, MD