Endoxifen
Endoxifen is an active metabolite of the drug tamoxifen that is used in the treatment of estrogen receptor-positive breast cancer in pre- and post-menopausal women. It is currently being studied for its potential as a treatment for other types of cancer.
Pharmacology[edit | edit source]
Endoxifen is a selective estrogen receptor modulator (SERM) that has been shown to inhibit the growth of estrogen receptor-positive breast cancer cells. It is also a potent inhibitor of cytochrome P450 2D6 (CYP2D6), an enzyme that is involved in the metabolism of tamoxifen.
Clinical Use[edit | edit source]
Endoxifen is used in the treatment of estrogen receptor-positive breast cancer in pre- and post-menopausal women. It is also being studied for its potential as a treatment for other types of cancer.
Side Effects[edit | edit source]
The most common side effects of endoxifen include hot flashes, nausea, and vomiting. Less common side effects include hair loss, joint pain, and fatigue.
Research[edit | edit source]
Research is currently being conducted to determine the effectiveness of endoxifen in treating other types of cancer. Preliminary results suggest that it may be effective in treating prostate cancer, ovarian cancer, and lung cancer.
See Also[edit | edit source]
| Endoxifen Resources | |
|---|---|
|
 |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
WikiMD is not a substitute for professional medical advice. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
