Endrisone
Endrisone is a corticosteroid used in the treatment of various inflammatory and autoimmune conditions. It is a synthetic glucocorticoid, a class of steroids that are produced in the adrenal gland and have a wide range of effects on the body, including anti-inflammatory and immunosuppressive actions.
Pharmacology[edit | edit source]
Endrisone works by mimicking the effects of natural glucocorticoids. It binds to and activates the glucocorticoid receptor, a type of nuclear receptor that regulates the expression of genes involved in inflammation and immune response. By doing this, endrisone reduces the production of inflammatory chemicals and suppresses the activity of the immune system.
Uses[edit | edit source]
Endrisone is used to treat a variety of conditions that involve inflammation or overactivity of the immune system. These include rheumatoid arthritis, lupus, asthma, allergies, and certain skin conditions. It is also used to prevent organ rejection in people who have undergone organ transplant.
Side Effects[edit | edit source]
Like all corticosteroids, endrisone can have a number of side effects. These can include weight gain, mood changes, increased risk of infections, and osteoporosis. Long-term use can also lead to Cushing's syndrome, a condition characterized by a round face, upper body obesity, and thinning of the skin.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD