Enilconazole

Enilconazole

Enilconazole (also known as Imaverol) is a fungicide and antimycotic agent primarily used in veterinary medicine. It is a synthetic compound of the imidazole class, which is known for its broad-spectrum antifungal activity.

Chemistry

Enilconazole is a synthetic imidazole derivative. Imidazoles are a class of compounds that contain a five-membered ring structure composed of three carbon atoms and two nitrogen atoms at non-adjacent positions. The chemical formula of enilconazole is C14H15Cl2N3O.

Pharmacology

Enilconazole exhibits its antifungal activity by inhibiting the synthesis of ergosterol, a critical component of fungal cell membranes. This disruption leads to increased membrane permeability, causing leakage of essential intracellular components and ultimately cell death.

Uses

Enilconazole is primarily used in veterinary medicine for the treatment of fungal infections. It is particularly effective against dermatophytes, which are a group of fungi that cause skin, hair, and nail infections. It is also used in the treatment of aspergillosis in birds and mycosis in dogs.

Safety

Enilconazole is generally well-tolerated in animals. However, it can cause skin irritation in humans and should be handled with care. It is recommended to wear protective clothing and gloves when handling enilconazole.

See also

• Imidazole
• Fungicide
• Antimycotic