Epithelioid hemangioma

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Epithelioid hemangioma is a rare, benign vascular tumor that typically presents as a solitary nodule or papule on the head, neck, or extremities. It is characterized by the presence of epithelioid endothelial cells, which are cells that line the blood vessels and have a characteristic "epithelioid" appearance.

Clinical presentation[edit | edit source]

Epithelioid hemangioma typically presents as a solitary nodule or papule on the head, neck, or extremities. The lesion may be red, brown, or blue in color and may be associated with pain or tenderness. The size of the lesion can vary, but it is typically less than 2 cm in diameter.

Pathology[edit | edit source]

Histologically, epithelioid hemangioma is characterized by the presence of epithelioid endothelial cells. These cells line the blood vessels and have a characteristic "epithelioid" appearance. They are larger than normal endothelial cells and have abundant eosinophilic cytoplasm and large, round nuclei. The blood vessels in the tumor are often surrounded by a dense inflammatory infiltrate, which may include lymphocytes, plasma cells, and eosinophils.

Diagnosis[edit | edit source]

The diagnosis of epithelioid hemangioma is typically made based on the clinical presentation and histological findings. Other diagnostic tests, such as immunohistochemistry, may be used to confirm the diagnosis and rule out other conditions.

Treatment[edit | edit source]

Treatment for epithelioid hemangioma typically involves surgical excision of the lesion. In some cases, other treatments, such as radiation therapy or systemic therapy, may be used.

Prognosis[edit | edit source]

The prognosis for individuals with epithelioid hemangioma is generally good. The tumor is benign and does not typically spread to other parts of the body. However, recurrence after treatment is possible.

Epithelioid hemangioma Resources
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Contributors: Prab R. Tumpati, MD