Epithelioid hemangioma

Epithelioid hemangioma
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Synonyms	Angiolymphoid hyperplasia with eosinophilia
Pronounce	N/A
Specialty	N/A
Symptoms	Red or brown papules or nodules
Complications	Rarely, local recurrence
Onset	Any age, commonly young adults
Duration	Chronic
Types	N/A
Causes	Unknown
Risks
Diagnosis	Clinical examination, histopathology
Differential diagnosis	Pyogenic granuloma, Kaposi's sarcoma, Angiosarcoma
Prevention	N/A
Treatment	Surgical excision, laser therapy
Medication	N/A
Prognosis	Excellent
Frequency	Rare
Deaths	N/A

Epithelioid hemangioma is a rare, benign vascular tumor that primarily affects the skin and subcutaneous tissues. It is characterized by the proliferation of blood vessels with distinctive epithelioid endothelial cells. This condition is also known as angiolymphoid hyperplasia with eosinophilia.

Clinical Presentation

Epithelioid hemangioma typically presents as red or brown papules or nodules, often located on the head and neck region. These lesions can be solitary or multiple and may vary in size. Patients may experience itching or tenderness at the site of the lesions.

Pathophysiology

The exact cause of epithelioid hemangioma is unknown. Histologically, the lesions are characterized by well-formed blood vessels lined by plump, epithelioid endothelial cells. There is often a prominent inflammatory infiltrate, including eosinophils, which contributes to the alternative name of the condition.

Diagnosis

Diagnosis of epithelioid hemangioma is primarily based on clinical examination and confirmed by histopathological analysis. A biopsy of the lesion typically reveals the characteristic vascular proliferation and inflammatory infiltrate.

Differential Diagnosis

The differential diagnosis for epithelioid hemangioma includes:

• Pyogenic granuloma
• Kaposi's sarcoma
• Angiosarcoma
• Kimura's disease

Treatment

The primary treatment for epithelioid hemangioma is surgical excision, which is usually curative. Other treatment options include laser therapy and corticosteroid injections. Recurrence is rare but can occur.

Prognosis

The prognosis for patients with epithelioid hemangioma is excellent, as the condition is benign and does not metastasize. However, local recurrence can occur if the lesion is not completely excised.

Also see

• Hemangioma
• Vascular tumors
• Benign tumors
• Dermatology