Histopathology

Histopathology[edit | edit source]

Histopathology refers to the microscopic examination of tissue in order to study the manifestations of disease. Specifically, in clinical medicine, histopathology refers to the examination of a biopsy or surgical specimen by a pathologist, after the specimen has been processed and histological sections have been placed onto glass slides.

Histopathology of thyroid parenchyma with autolytic changes

Overview[edit | edit source]

In contrast to cytopathology, which is the study of individual cells, histopathology studies the whole tissue architecture, and hence the name. Histopathology can also be used to study the pathology of diseases in animals.

Process[edit | edit source]

The process begins with the surgical removal of a tissue specimen, its processing and then subsequent microscopic examination. The pathologist's interpretation of what they see under the microscope, combined with the patient's clinical history, allows for a definitive diagnosis.

Techniques[edit | edit source]

The most common technique used in histopathology is histological staining. The most widely used stain in histopathology is a combination of hematoxylin and eosin (often abbreviated H&E). Other stains and techniques such as immunohistochemistry, in situ hybridization, and other molecular techniques can also be used.

Applications[edit | edit source]

Histopathology is used in a wide range of applications, including research, forensic investigation, and in the diagnosis of disease in medicine.

References[edit | edit source]

Histopathology Resources
Need Help Finding a Doctor? Need help finding a doctor or specialist anywhere in the world? Explore our world directory. WikiMD's DocFinder can assist you in locating millions of physicians.	Medical Knowledge Access the latest research - Most recent articles Ongoing trials.