Epsilonretrovirus

Epsilonretrovirus is a genus of retroviruses that primarily infect fish. This genus is part of the family Retroviridae, which includes several other genera of retroviruses. Epsilonretroviruses are unique among retroviruses in that they have been found to infect only fish species, unlike other retroviruses which can infect a variety of animal species.

Characteristics

Epsilonretroviruses are enveloped viruses with icosahedral geometries. The diameter is around 80-100 nm. Genomes are linear and non-segmented, around 8-10kb in length. The genome codes for proteins that are involved in the replication of the virus, including reverse transcriptase, which is a characteristic enzyme of retroviruses.

Life Cycle

The life cycle of epsilonretroviruses is similar to that of other retroviruses. The virus attaches to the host cell, enters the cell, and then uses its reverse transcriptase enzyme to convert its RNA genome into DNA. This DNA is then integrated into the host cell's genome, where it can be transcribed and translated to produce new virus particles.

Pathology

Epsilonretroviruses are known to cause tumors in fish, particularly walleye and snakehead fish. The mechanism by which these viruses cause tumors is not fully understood, but it is thought to involve the integration of the viral DNA into the host cell's genome, which can disrupt normal cellular functions and lead to uncontrolled cell growth.

See Also

• Retrovirus
• Retroviridae
• Walleye dermal sarcoma virus
• Snakehead retrovirus

References

Epsilonretrovirus Resources
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