Etaminile

From WikiMD.com Medical Encyclopedia

Overview of the drug Etaminile


Etaminile
[[File:
Chemical structure of Etaminile
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CAS Number 77-15-6
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Etaminile is a pharmaceutical drug that was developed in the mid-20th century. It is primarily known for its use as a stimulant and has been studied for its effects on the central nervous system.

Chemical Properties[edit | edit source]

Etaminile is classified as a piperidine derivative. Its chemical structure includes a benzilate moiety attached to a piperidine ring, with an ethyl group substituting the nitrogen atom. This configuration contributes to its pharmacological activity as a stimulant.

Pharmacology[edit | edit source]

Etaminile acts as a central nervous system stimulant. It is believed to exert its effects by influencing the release and uptake of neurotransmitters such as dopamine and norepinephrine. These actions result in increased alertness, reduced fatigue, and enhanced cognitive performance.

Medical Uses[edit | edit source]

Historically, Etaminile was used in the treatment of conditions such as narcolepsy and attention deficit hyperactivity disorder (ADHD). However, its use has declined due to the development of newer medications with improved safety profiles.

Side Effects[edit | edit source]

Common side effects of Etaminile include insomnia, anxiety, and tachycardia. In some cases, it may cause more severe reactions such as hypertension and cardiac arrhythmias. Due to these potential adverse effects, its use is generally limited.

Legal Status[edit | edit source]

Etaminile is not widely used today and is subject to regulation in many countries. It is classified as a controlled substance in some jurisdictions due to its potential for abuse and dependence.

Synthesis[edit | edit source]

The synthesis of Etaminile involves the reaction of benzilic acid with piperidine, followed by the introduction of an ethyl group to the nitrogen atom. This process requires careful control of reaction conditions to ensure the desired product is obtained.

Related Compounds[edit | edit source]

Etaminile is structurally related to other piperidine derivatives such as methylphenidate and pemoline. These compounds share similar stimulant properties and have been used in the treatment of similar medical conditions.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD