Ethylamphetamine

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Ethylamphetamine


Ethylamphetamine is a stimulant drug belonging to the amphetamine class of psychoactive substances. It is known for its central nervous system (CNS) stimulating properties similar to those of other amphetamines such as methamphetamine and dextroamphetamine. Ethylamphetamine acts by increasing the release and inhibiting the reuptake of neurotransmitters such as dopamine, norepinephrine, and serotonin in the brain, leading to increased arousal, alertness, and euphoria.

The chemical structure of ethylamphetamine differs from that of methamphetamine by the addition of an ethyl group to the nitrogen atom. This slight modification can influence its pharmacokinetic and pharmacodynamic properties, including its potency, duration of action, and side effects.

Ethylamphetamine has been used in the past for various medical purposes, including as an anorectic for weight loss and as a treatment for narcolepsy and attention deficit hyperactivity disorder (ADHD). However, due to its potential for abuse and the development of safer alternatives, its medical use has become less common.

Recreational use of ethylamphetamine can lead to adverse effects such as increased heart rate, elevated blood pressure, hyperthermia, and in severe cases, psychosis, cardiac arrest, and death. Its addictive potential is also a significant concern, with users risking dependence and withdrawal symptoms upon cessation.

Legal status varies by country, but ethylamphetamine is often controlled under various drug laws, making its non-prescribed possession, sale, or manufacture illegal.


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Contributors: Prab R. Tumpati, MD