Etofylline nicotinate

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Etofylline nicotinate

Etofylline nicotinate is a pharmaceutical drug used in the treatment of various cardiovascular diseases. It is a combination of two active ingredients: etofylline and nicotinic acid, also known as niacin.

Pharmacology

Etofylline is a bronchodilator that works by relaxing the muscles in the walls of the airways. This opens the airways and makes breathing easier. Nicotinic acid, on the other hand, is a form of vitamin B3 that has several important functions in the body, including improving blood circulation and reducing cholesterol levels.

Indications

Etofylline nicotinate is primarily used in the treatment of angina pectoris, a type of chest pain caused by reduced blood flow to the heart. It is also used to treat intermittent claudication, a condition that causes pain in the legs due to inadequate blood flow. In addition, it is used in the management of peripheral vascular disease, a circulation disorder that affects blood vessels outside of the heart and brain.

Side Effects

Like all medications, etofylline nicotinate can cause side effects. Common side effects include flushing, dizziness, and upset stomach. More serious side effects can include irregular heartbeat, low blood pressure, and severe allergic reactions.

Contraindications

Etofylline nicotinate is contraindicated in patients with severe hypotension, peptic ulcer disease, and in those who have had a recent myocardial infarction. It should also be used with caution in patients with liver disease or kidney disease, as these conditions can affect the metabolism and excretion of the drug.

Interactions

Etofylline nicotinate can interact with other medications, including other vasodilators, antihypertensives, and anticoagulants. These interactions can increase the risk of side effects or reduce the effectiveness of the medications.

See Also

• Etofylline
• Nicotinic acid
• Angina pectoris
• Intermittent claudication
• Peripheral vascular disease