Evzio

Evzio is a prescription medication used for the emergency treatment of known or suspected opioid overdose. It contains the active ingredient naloxone, which is an opioid antagonist. Evzio is designed for rapid administration by non-medical personnel, such as family members or caregivers, in situations where opioid overdose is suspected.

Mechanism of Action

Evzio works by binding to the same receptors in the brain that opioids bind to, effectively displacing the opioid molecules and reversing their effects. This can rapidly restore normal respiration in a person whose breathing has slowed or stopped as a result of opioid overdose.

Administration

Evzio is available as a pre-filled auto-injector, which is designed to be easy to use. The device provides verbal instructions to guide the user through the injection process. It is typically injected into the outer thigh, and can be administered through clothing if necessary.

Indications

Evzio is indicated for the emergency treatment of known or suspected opioid overdose, as manifested by respiratory and/or central nervous system depression. It is intended for immediate administration as emergency therapy in settings where opioids may be present.

Side Effects

Common side effects of Evzio include:

• Nausea
• Vomiting
• Sweating
• Increased heart rate
• Tremors

In some cases, the rapid reversal of opioid effects can lead to acute withdrawal symptoms in individuals who are opioid-dependent.

Storage

Evzio should be stored at room temperature, away from light and moisture. It should be kept in its outer case until ready to use to protect it from damage.

Related Pages

• Naloxone
• Opioid overdose
• Opioid antagonist
• Opioid epidemic
• Emergency medical services

See Also

• Narcan
• Opioid use disorder
• Harm reduction