FCGBP

Ideogram human chromosome 19

FCGBP

FCGBP is a gene that encodes the Fc fragment of IgG binding protein. This gene is located on chromosome 9 in humans. The protein encoded by FCGBP is involved in binding to the Fc portion of immunoglobulin G (IgG), which plays a crucial role in the immune response.

Function

The FCGBP gene encodes a protein that is involved in binding to the Fc portion of IgG. This interaction is important for various immune functions, including antibody-dependent cellular cytotoxicity and phagocytosis. Additionally, FCGBP may play a role in regulating the immune response and inflammation.

Clinical Significance

Mutations in the FCGBP gene have been associated with certain autoimmune diseases and inflammatory conditions. Studies have shown that alterations in FCGBP expression levels may contribute to the pathogenesis of these disorders. Further research is needed to fully understand the implications of FCGBP variations in disease development and progression.

Interactions

The protein encoded by FCGBP interacts with the Fc portion of IgG, as well as other immune-related molecules. These interactions are essential for the proper functioning of the immune system and the coordination of immune responses against pathogens and foreign substances.