Fenoxycarb

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Fenoxycarb

Fenamiphos is an organophosphate pesticide used primarily to control nematode infestations in soil. It functions by disrupting the nervous system of nematodes, leading to their death. Fenamiphos is applied to a variety of crops, including vegetables, fruits, and ornamentals, to protect them from damage caused by these pests. However, due to its high toxicity to humans and non-target organisms, its use is highly regulated in many countries.

Chemistry[edit | edit source]

Fenamiphos belongs to the chemical class of organophosphates, compounds that act as acetylcholinesterase inhibitors. By inhibiting this enzyme, fenamiphos disrupts the normal function of the nervous system in nematodes, causing paralysis and death. The chemical formula for fenamiphos is C13H22NO3PS, and it is known for its systemic action, meaning it can be absorbed and transported within the plant to provide protection against nematodes attacking roots and other underground parts of the plant.

Usage[edit | edit source]

Fenamiphos is used in agricultural settings to control a wide range of nematode species. It is applied directly to the soil around susceptible crops or incorporated into the soil before planting. The pesticide is effective against many types of nematodes, including root-knot nematodes, cyst nematodes, and others that pose significant threats to agricultural productivity.

Regulation and Environmental Impact[edit | edit source]

Due to its toxicity, the use of fenamiphos is subject to strict regulations in many countries. It is classified as a highly hazardous pesticide by the World Health Organization (WHO) and has been banned or restricted in several jurisdictions. Fenamiphos is toxic to aquatic organisms, birds, and beneficial insects, raising concerns about its environmental impact, particularly its potential to contaminate water sources and harm non-target species.

Health Risks[edit | edit source]

Exposure to fenamiphos can pose significant health risks to humans. As an organophosphate, it can inhibit acetylcholinesterase in humans, leading to a range of symptoms from mild (headache, dizziness) to severe (respiratory distress, convulsions) depending on the level of exposure. Agricultural workers and others who handle fenamiphos or enter treated areas are at risk of exposure through inhalation, ingestion, or skin contact.

Alternatives and Management[edit | edit source]

Given the environmental and health risks associated with fenamiphos, there is a growing interest in finding safer alternatives and adopting integrated pest management (IPM) practices. Biological control agents, crop rotation, and resistant crop varieties are among the strategies being explored to manage nematode populations without relying on highly toxic chemicals.


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Contributors: Prab R. Tumpati, MD