Ferredoxin

From WikiMD's Wellness Encyclopedia

Ferredoxin


Ferredoxin is a protein that plays a critical role in the electron transport chain, which is a key component of photosynthesis and cellular respiration in organisms. Ferredoxins are iron-sulfur proteins that mediate electron transfer in a range of metabolic reactions. They are found in the chloroplasts of plants, the mitochondria of animals, and in the cells of bacteria and archaea.

The structure of ferredoxin consists of a polypeptide chain that binds iron and sulfur atoms to form iron-sulfur clusters. These clusters are responsible for the electron transfer activity of the protein. The most common type of cluster found in ferredoxin is the [2Fe-2S] cluster, although some ferredoxins contain [4Fe-4S] clusters.

Ferredoxins function by accepting or donating electrons, typically from a reductase enzyme to an oxidase enzyme, in various biochemical pathways. In photosynthesis, ferredoxin is reduced (gains electrons) by the photosystem I and then donates these electrons to the enzyme NADP+ reductase, which uses them to reduce NADP+ to NADPH, a key molecule in the synthesis of carbohydrates.

In nitrogen fixation, ferredoxin provides electrons for the reduction of nitrogen gas (N2) to ammonia (NH3) by the enzyme nitrogenase. This process is crucial for incorporating atmospheric nitrogen into organic compounds and supports the growth of plants and the productivity of ecosystems.

Ferredoxins also play a role in the sulfur metabolism of some organisms, where they participate in the reduction of sulfite to sulfide in the process of synthesizing cysteine, an important amino acid.

Given their widespread presence and essential functions, ferredoxins are considered fundamental components of life, especially in the context of energy conversion and the biosynthesis of critical biomolecules.

WikiMD
Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD

Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD

WikiMD's Wellness Encyclopedia

Let Food Be Thy Medicine
Medicine Thy Food - Hippocrates

Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.

Contributors: Prab R. Tumpati, MD