Flutrimazole

Flutrimazole is a type of antifungal medication used to treat a variety of fungal infections. It belongs to the azole class of antifungal agents, which work by inhibiting the growth of fungi by interfering with the production of the fungal cell membrane.

Mechanism of Action

Flutrimazole works by inhibiting the enzyme cytochrome P450 14α-demethylase. This enzyme is necessary for the conversion of lanosterol to ergosterol, an essential component of the fungal cell membrane. When ergosterol is depleted, it results in abnormal fungal cell membranes, disrupting their function and inhibiting fungal growth.

Uses

Flutrimazole is primarily used in the treatment of skin infections caused by fungi, including tinea pedis (athlete's foot), tinea cruris (jock itch), and tinea corporis (ringworm). It can also be used to treat candidiasis, a yeast infection that can affect various parts of the body.

Side Effects

Like all medications, flutrimazole can cause side effects. Common side effects include skin irritation, burning, and redness at the application site. Less common side effects can include blistering, peeling, or a rash. If these side effects persist or worsen, medical attention should be sought.

Precautions

Before using flutrimazole, it is important to inform the healthcare provider of any allergies or medical conditions, as well as any other medications being taken. It should not be used on broken or infected skin unless directed by a healthcare provider.

See Also

• Antifungal medication
• Azole
• Tinea pedis
• Tinea cruris
• Tinea corporis
• Candidiasis