Follicular antrum

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Follicular antrum is a fluid-filled cavity that forms within the ovarian follicle during the later stages of its maturation. The antrum is a key component of the follicle's structure and plays a crucial role in the process of ovulation.

Etymology[edit | edit source]

The term "antrum" is derived from the Latin word "antrum," which means "cave" or "cavern." This is a fitting description of the antrum's role as a cavity within the ovarian follicle.

Structure[edit | edit source]

The follicular antrum is a large, fluid-filled cavity that forms within the ovarian follicle during the later stages of its maturation. It is surrounded by the granulosa cells, which secrete the fluid that fills the antrum. The antrum's size and the amount of fluid it contains can vary depending on the stage of the menstrual cycle.

Function[edit | edit source]

The primary function of the follicular antrum is to facilitate the process of ovulation. The fluid within the antrum exerts pressure on the oocyte, helping to push it out of the follicle and into the fallopian tube during ovulation. The antrum also provides a supportive environment for the oocyte as it matures.

Clinical significance[edit | edit source]

Abnormalities in the formation or function of the follicular antrum can lead to a variety of reproductive disorders. For example, polycystic ovary syndrome (PCOS) is characterized by the presence of multiple small antral follicles that fail to mature properly. This can result in irregular menstrual cycles and infertility.

See also[edit | edit source]

References[edit | edit source]

Follicular antrum Resources
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Contributors: Prab R. Tumpati, MD