Fonsecaea pedrosoi
Fonsecaea pedrosoi is a species of fungus that belongs to the Dematiaceae family. It is a major causative agent of chromoblastomycosis, a chronic skin infection prevalent in tropical and subtropical regions.
Taxonomy[edit | edit source]
The genus Fonsecaea was named in honor of the Brazilian mycologist Adolpho Lutz. Fonsecaea pedrosoi is one of the four species in this genus, the others being Fonsecaea monophora, Fonsecaea nubica, and Fonsecaea multimorphosa.
Morphology[edit | edit source]
Fonsecaea pedrosoi is characterized by its darkly pigmented hyphae and conidia. The conidia are produced on short, unbranched conidiophores, and are typically round or oval in shape.
Pathogenicity[edit | edit source]
Fonsecaea pedrosoi is a dermatophyte, meaning it infects the skin, hair, and nails. It is the most common cause of chromoblastomycosis, a condition characterized by wart-like skin lesions that can become chronic if left untreated. The fungus is believed to enter the body through a break in the skin, often as a result of a thorn prick or other minor injury.
Treatment[edit | edit source]
Treatment of infections caused by Fonsecaea pedrosoi typically involves a combination of antifungal medications and surgical removal of the affected tissue. The antifungal drugs itraconazole and terbinafine are commonly used. In severe cases, amphotericin B may be administered.
Epidemiology[edit | edit source]
Chromoblastomycosis caused by Fonsecaea pedrosoi is most common in tropical and subtropical regions, particularly in rural areas where individuals are more likely to come into contact with the fungus in the soil. The disease is not contagious and cannot be transmitted from person to person.
See also[edit | edit source]
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Contributors: Prab R. Tumpati, MD