Fornix

C-shaped bundle of nerve fibers in the brain

Fornix

Scheme of rhinencephalon. (Fornix labeled at center top.)
Latin	Fornix cerebri
Part of	Limbic system
System	Central nervous system

The fornix is a C-shaped bundle of nerve fibers in the brain that acts as the major output tract of the hippocampus. It is part of the limbic system and plays a crucial role in cognition and memory processes.

Anatomy

The fornix is divided into several parts:

• The crura of the fornix, which begin in the hippocampus.
• The body of the fornix, which is the main part of the structure.
• The columns of the fornix, which extend to the mammillary bodies.

The fornix arches over the thalamus and under the corpus callosum, connecting the hippocampus to the mammillary bodies and the septal nuclei.

Function

The primary function of the fornix is to transmit information from the hippocampus to other parts of the brain, particularly the mammillary bodies and the anterior nuclei of the thalamus. This pathway is essential for the consolidation of long-term memory.

Clinical Significance

Damage to the fornix can result in memory disorders, such as anterograde amnesia, where the ability to form new memories is impaired. This can occur due to various conditions, including traumatic brain injury, stroke, or neurodegenerative diseases.

Related Structures

• Hippocampus
• Mammillary bodies
• Thalamus
• Limbic system
• Corpus callosum

See Also

• Limbic system
• Hippocampus
• Memory
• Neuroanatomy