Fosnetupitant chloride

Fosnetupitant chloride

Fosnetupitant chloride is a drug used in the treatment of chemotherapy-induced nausea and vomiting. It is a member of the neurokinin-1 (NK1) receptor antagonists class of drugs. Fosnetupitant chloride is often used in combination with other antiemetic drugs to enhance efficacy.

Pharmacology

Fosnetupitant chloride works by blocking the neurokinin-1 (NK1) receptor, a protein found in the brain that is involved in vomiting. By blocking this receptor, fosnetupitant chloride can prevent the body from reacting to substances that would normally trigger vomiting.

Clinical Use

Fosnetupitant chloride is used in combination with other antiemetic drugs to prevent nausea and vomiting caused by chemotherapy. It is typically used in patients who are receiving highly emetogenic chemotherapy, or chemotherapy that has a high risk of causing nausea and vomiting.

Side Effects

Common side effects of fosnetupitant chloride include fatigue, constipation, and headache. In rare cases, it can cause serious side effects such as severe allergic reactions and skin reactions.

See Also

• Neurokinin-1 (NK1) receptor antagonists
• Chemotherapy-induced nausea and vomiting
• Antiemetic

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