Free nerve ending
Free nerve endings are microscopic sensory nerve endings in the skin that are not connected to any specific sensory receptor
Layer of skin[edit | edit source]
The epidermis is innervated with sensory nerves.
Purpose[edit | edit source]
These nerves sense and transmit heat, pain, and other noxious sensations.
Abnormal function[edit | edit source]
When they are not functioning properly sensations such as numbness, pins-and-needles, pain, tingling, or burning may be felt.
Assessment with skin biopsy[edit | edit source]
When evaluating a skin biopsy, total number, contiguity, diameter, branching, swelling, and overall health of the sensory nerves are assessed.
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Contributors: Prab R. Tumpati, MD
