Functional molecular infection epidemiology

Functional Molecular Infection Epidemiology (FMIE) is an emerging area of medicine that entails the study of pathogen genes and genomes in the context of their functional association with the host niches (adhesion, invasion, adaptation) and the complex interactions they trigger within the host immune system (cell signaling, apoptosis) to culminate in varied outcomes of the infection. This can also be defined as the correlation of genetic variations in a pathogen or its respective host with a unique function that is important for disease severity, disease progression, or host susceptibility to a particular pathogen. Functional epidemiology implies not only descriptive host-pathogen genomic associations, but rather the interplay between pathogen and host genomic variations to functionally de

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