Furanose
Furanose is a type of monosaccharide that has a chemical structure resembling the organic compound furan. The term "furanose" derives from its similarity to the oxygen heterocycle furan, but the furanose ring does not have double bonds, unlike furan. The furanose ring structure is commonly found in nature and is very important in many biological systems.
Structure and Formation[edit | edit source]
Furanose forms a five-membered ring, similar to the structure of furan. This ring is formed through a process known as ring closure, where a carbonyl group in the sugar reacts with a hydroxyl group to form a hemiacetal or hemiketal, creating the ring structure.
The resulting structure can exist in two forms, known as anomers. These are the alpha (α) and beta (β) forms, which differ in the configuration of the hydroxyl group at the anomeric carbon. The α-anomer has the hydroxyl group below the plane of the ring, while the β-anomer has it above the plane.
Biological Importance[edit | edit source]
Furanose forms are prevalent in many biologically important molecules. For example, the furanose form of ribose is a key component of RNA (ribonucleic acid), and the furanose form of deoxyribose is a key component of DNA (deoxyribonucleic acid).
Furanose forms are also found in many oligosaccharides and polysaccharides, including cellulose and starch. These molecules play crucial roles in energy storage and structural support in many organisms.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD