Fusidane

Fusidane

0Fusidane is a type of steroid that is used in the production of antibiotics, specifically fusidic acid. It is derived from the fungus Fusidium coccineum and has been used in medicine since the 1960s.

History

Fusidane was first isolated in 1960 from the fungus Fusidium coccineum. The discovery of fusidane led to the development of fusidic acid, a potent antibiotic that is still in use today.

Structure and Properties

Fusidane is a steroid with a unique structure that includes a 16-membered lactone ring. This structure is responsible for its antibiotic properties. Fusidane is a white, crystalline powder that is soluble in ethanol and chloroform, but insoluble in water.

Medical Use

Fusidane is used in the production of fusidic acid, a potent antibiotic that is effective against a wide range of bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). Fusidic acid works by inhibiting the synthesis of bacterial proteins, which prevents the bacteria from growing and reproducing.

Production

Fusidane is produced by the fungus Fusidium coccineum. The fungus is grown in a nutrient medium, and the fusidane is then extracted and purified. The purified fusidane is then used to produce fusidic acid.

See Also

• Fusidic acid
• Steroid
• Antibiotic
• Fusidium coccineum