Fusion mechanism

From WikiMD's Wellness Encyclopedia

A fusion mechanism is any mechanism by which cell fusion or virus cell fusion takes place, as well as the machinery that facilitates these processes.

What is cell fusion?[edit | edit source]

Cell fusion is the formation of a hybrid cell from two separate cells.

What are the types?[edit | edit source]

  • There are three major actions taken in both virus cell fusion and cell - cell fusion: the dehydration of polar head groups, the promotion of a hemifusion stalk, and the opening and expansion of pores between fusing cells.
  • Virus-cell fusions occur during infections of several viruses that are healthconcerns relevant today.
  • Some of these include HIV, Ebola, and influenza. For example, HIV infects by fusing with the membranes of immune system cells.
  • In order for HIV to fuse with a cell, it must be able to bind to the receptors CD4, CCR5, and CXCR4.
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Contributors: Prab R. Tumpati, MD