GR-113808

GR-113808 is a serotonin receptor antagonist that is used in scientific research. It is most commonly used in studies involving the gastrointestinal tract, as it has a high affinity for the 5-HT4 receptor, a type of serotonin receptor that is found in high concentrations in the gastrointestinal tract.

Mechanism of Action

GR-113808 works by binding to the 5-HT4 receptor and preventing serotonin from activating it. This can have a variety of effects, depending on the specific function of the 5-HT4 receptor in the tissue where it is located. In the gastrointestinal tract, for example, blocking the 5-HT4 receptor can slow down the movement of food through the digestive system.

Use in Research

Due to its high affinity for the 5-HT4 receptor, GR-113808 is often used in research studies that are investigating the role of this receptor in various physiological processes. For example, it has been used in studies looking at the role of the 5-HT4 receptor in the regulation of gastric motility and intestinal secretion.

Side Effects

As with any drug, GR-113808 can have side effects. These can vary depending on the dose and the individual, but may include nausea, vomiting, and abdominal pain. It is important to note that these side effects are usually mild and temporary.

See Also

• 5-HT4 receptor
• Serotonin
• Receptor antagonist