Gallium-68

Gallium-68 (68Ga) is a radioactive isotope of gallium that is used in the medical field, particularly in nuclear medicine. It is a positron emitter with a half-life of 68 minutes.

Production[edit | edit source]

Gallium-68 is produced from a 68Ge/68Ga generator. The parent isotope, germanium-68, decays to 68Ga through electron capture, with a half-life of 270.8 days. The 68Ga thus produced is in a highly ionic state and can be used immediately, making it suitable for medical applications.

Medical Applications[edit | edit source]

In nuclear medicine, Gallium-68 is used in PET imaging. It is used in the synthesis of radiopharmaceuticals, such as Gallium-68 DOTATATE and Gallium-68 PSMA-11, which are used in the diagnosis and treatment of certain types of cancer, including neuroendocrine tumors and prostate cancer.

Advantages[edit | edit source]

The short half-life of Gallium-68 allows for rapid imaging, while its positron emission allows for high-resolution, three-dimensional imaging. Its production from a generator is also advantageous, as it eliminates the need for an on-site cyclotron, reducing costs and logistical issues.

Safety[edit | edit source]

As a radioactive isotope, Gallium-68 does pose some risks. However, its short half-life and the small amounts used in medical procedures minimize these risks. It is important that Gallium-68 is handled and disposed of properly to ensure safety.