Glycosidic bond

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Glycosidic bond is a type of covalent bond that joins a carbohydrate (sugar) molecule to another group, which may or may not be another carbohydrate.

Overview[edit | edit source]

A glycosidic bond is formed between the anomeric carbon of a carbohydrate and the hydroxyl group of another molecule. The bond is synthesized by dehydration synthesis, which involves the elimination of a water molecule from the functional groups that form the bond.

Types of Glycosidic Bonds[edit | edit source]

There are two types of glycosidic bonds: alpha (α) and beta (β). The distinction between the two is based on the position of the bonded carbon atom.

Alpha Glycosidic Bond[edit | edit source]

In an alpha glycosidic bond, the OH group on the anomeric carbon is on the opposite side (trans) of the ring oxygen from the CH2OH moiety. This is the case in starch and glycogen.

Beta Glycosidic Bond[edit | edit source]

In a beta glycosidic bond, the OH group on the anomeric carbon is on the same side (cis) of the ring oxygen as the CH2OH moiety. This is the case in cellulose and chitin.

Role in Biology[edit | edit source]

Glycosidic bonds play a crucial role in the structure and function of carbohydrates in living organisms. They are responsible for the formation of disaccharides and polysaccharides, and they also play a role in the formation of DNA and RNA.

See Also[edit | edit source]

Glycosidic bond Resources
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Contributors: Prab R. Tumpati, MD