HIST1H2BG
HIST1H2BG
HIST1H2BG is a gene that encodes a member of the histone H2B family. Histones are proteins that play a crucial role in packaging DNA into chromatin, which is essential for the regulation of gene expression and other cellular processes.
Function[edit | edit source]
The protein encoded by HIST1H2BG is a core component of nucleosomes, the basic units of chromatin. Nucleosomes consist of DNA wrapped around histone proteins, including histone H2B. This gene is involved in the regulation of gene transcription and other chromatin-related processes.
Structure[edit | edit source]
HIST1H2BG is located on chromosome 6 in humans. It contains the necessary information to produce the histone H2B protein. Histone H2B is one of the core histone proteins that form the octameric structure of the nucleosome.
Role in Disease[edit | edit source]
Mutations in HIST1H2BG have been associated with certain diseases, although research on the specific implications is ongoing. Understanding the role of this gene in disease processes may provide insights into potential therapeutic targets.
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD
