Haloxon
Haloxon is an organophosphate compound that is used as an anthelmintic agent. It is primarily used in veterinary medicine to treat parasitic worm infections in livestock.
Chemistry[edit | edit source]
Haloxon is a derivative of chloroxuron, a type of organophosphate. It is synthesized by the reaction of chloroxuron with sodium hydroxide and hydrogen peroxide. The resulting compound is a white crystalline powder that is soluble in water and most organic solvents.
Pharmacology[edit | edit source]
As an anthelmintic, Haloxon works by inhibiting the enzyme acetylcholinesterase in parasitic worms. This causes an accumulation of acetylcholine in the worm's nervous system, leading to paralysis and death of the parasite. Haloxon is effective against a variety of parasitic worms, including nematodes, cestodes, and trematodes.
Usage[edit | edit source]
Haloxon is primarily used in veterinary medicine to treat parasitic worm infections in livestock. It is administered orally, usually in the form of a drench. The dosage varies depending on the type and size of the animal, as well as the severity of the infection.
Safety[edit | edit source]
Like other organophosphates, Haloxon can be toxic if ingested or absorbed through the skin. It can cause a variety of symptoms in humans, including nausea, vomiting, diarrhea, and in severe cases, seizures or death. Proper protective equipment should be used when handling Haloxon, and it should be stored in a secure location out of reach of children and pets.
See also[edit | edit source]
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Contributors: Prab R. Tumpati, MD