Hanaoka Seishū
Japanese surgeon and pioneer of anesthesia
Hanaoka Seishū (Japanese: 華岡 青洲
, October 23, 1760 – October 21, 1835) was a Japanese surgeon of the Edo period who is celebrated for his pioneering work in the field of anesthesia. He is best known for being the first person to perform surgery using general anesthesia, which he achieved using a herbal formula he developed called tsūsensan.
Early Life and Education[edit]
Hanaoka Seishū was born in Kii Province, Japan, in 1760. He was the eldest son of a physician, and from a young age, he was exposed to the practice of medicine. His early education was in the traditional Japanese medical practices, but he later studied Chinese medicine and Western medicine, which were becoming increasingly influential in Japan at the time.
Medical Career[edit]
Hanaoka's medical career was marked by his innovative approach to surgery and anesthesia. He was particularly interested in the use of herbal medicine to alleviate pain during surgical procedures. This interest led him to study the properties of various plants, including Datura stramonium.

Development of Tsūsensan[edit]
Hanaoka's most significant contribution to medicine was the development of tsūsensan, an herbal anesthetic formula. This formula was a combination of several herbs, including Datura stramonium, which contains tropane alkaloids known for their sedative properties. Hanaoka's formula allowed him to perform surgeries that were previously impossible due to the pain involved.
Surgical Achievements[edit]
In 1804, Hanaoka performed the first documented surgery using general anesthesia. The patient was a woman named Kan Aiya, who had a breast tumor. The successful removal of the tumor marked a significant milestone in the history of surgery.
Legacy[edit]
Hanaoka Seishū's work laid the foundation for the development of modern anesthesia. His innovative use of herbal medicine to induce anesthesia was a precursor to the chemical anesthetics used today. Hanaoka's techniques and teachings were passed down through his students, influencing the practice of surgery in Japan and beyond.
Influence and Recognition[edit]
Hanaoka's contributions to medicine have been recognized both in Japan and internationally. He is often compared to Hua Tuo, an ancient Chinese physician known for his surgical innovations.

Related Pages[edit]
Sponsored Health Resource

W8MD Weight Loss, Sleep & MedSpa
Looking for physician-supervised weight loss, semaglutide, tirzepatide, or GLP-1 receptor agonist options? W8MD helps eligible patients in New York City, Brooklyn, New Jersey, Connecticut, Pennsylvania, Delaware, and greater Philadelphia with medical weight loss, sleep medicine, and long-term maintenance support.
GLP-1 specials: Affordable GLP-1 injections NYC and Philadelphia starting from $29.99/week and up for semaglutide with insurance accepted for qualifying visits, and $45/week and up for tirzepatide with insurance accepted for qualifying visits. Self-pay options start from $59.99/week and up for semaglutide and $69.99/week and up for tirzepatide.
- Medical weight loss NYC
- Affordable GLP-1 injections NYC
- Budget GLP-1 weight loss shots Philadelphia
- New Jersey medical weight loss
- NYC medical weight loss blog
- Philadelphia weight loss blog
- Sleep medicine and sleep apnea services
- W8MD MedSpa and wellness
Book a W8MD appointment · View GLP-1 specials
Paid promotional message. Eligibility, pricing, insurance coverage, medication availability, and results vary. Medical evaluation required.
Medical Disclaimer: WikiMD is for informational purposes only and is not a substitute for professional medical advice. Content may be inaccurate or outdated and should not be used for diagnosis or treatment. Always consult your healthcare provider for medical decisions. Verify information with trusted sources such as CDC.gov and NIH.gov. By using this site, you agree that WikiMD is not liable for any outcomes related to its content. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Translate page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian