Hexafluoroacetone

From WikiMD's Food, Medicine & Wellness Encyclopedia

Hexafluoroacetone (HFA) is a chemical compound with the formula (CF3)2CO. It is a colorless, nonflammable gas that is widely used in the chemical industry.

Chemical Properties[edit | edit source]

Hexafluoroacetone is a fluorocarbon derivative of acetone. It is a highly reactive compound due to the presence of three fluorine atoms on each methyl group. This makes it a useful reagent in various chemical reactions.

Synthesis[edit | edit source]

Hexafluoroacetone can be synthesized by the reaction of chlorodifluoromethane with sodium cyanide, followed by hydrolysis of the resulting nitrile. Another method involves the reaction of chlorotrifluoroethylene with sodium hydroxide.

Applications[edit | edit source]

Hexafluoroacetone is used as a building block in the synthesis of various fluorinated compounds. It is also used as a fluorinating agent in the production of pharmaceuticals and agrochemicals.

Safety[edit | edit source]

Due to its high reactivity, hexafluoroacetone can be hazardous if not handled properly. It can cause irritation to the eyes, skin, and respiratory tract. It is recommended to use appropriate personal protective equipment when handling this compound.

See Also[edit | edit source]


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Contributors: Prab R. Tumpati, MD