Hexarelin
Hexarelin is a synthetic peptide that has been shown to have both cardioprotective and growth hormone releasing properties. It is a six-amino acid peptide, and is structurally similar to ghrelin, a hormone that stimulates the release of growth hormone.
Mechanism of Action[edit | edit source]
Hexarelin acts on specific receptors in the pituitary gland and the hypothalamus to stimulate the release of growth hormone. Unlike other growth hormone releasing peptides, hexarelin does not lead to an increase in prolactin or cortisol levels.
Medical Uses[edit | edit source]
Hexarelin has been studied for its potential use in the treatment of growth hormone deficiency and cardiac dysfunction. It has been shown to improve cardiac function in animal models of heart failure, and may have potential as a treatment for patients with heart failure.
Side Effects[edit | edit source]
Common side effects of hexarelin include nausea, headache, and flushing. In rare cases, it can cause gynecomastia, or the enlargement of breast tissue in males.
Research[edit | edit source]
Research into the potential medical uses of hexarelin is ongoing. Some studies have suggested that it may have potential as a treatment for osteoporosis, due to its ability to stimulate the release of growth hormone, which plays a key role in bone health.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD