ICI-118,551
ICI-118,551 is a selective β2 adrenergic receptor antagonist. It is used in medical research to understand the function and action of the β2 receptor, due to its specificity and selectivity for this subtype. ICI-118,551 has been found to increase the contractility of the heart in studies on animals, suggesting potential therapeutic uses in heart failure. However, it is not currently used clinically for this purpose.
Pharmacology[edit | edit source]
ICI-118,551 is a selective antagonist for the β2 adrenergic receptor. This means it binds to these receptors and blocks their activation by agonists. It does not have significant activity at other adrenergic receptors, such as the β1 or β3 receptors.
Uses in Research[edit | edit source]
Due to its selectivity for the β2 receptor, ICI-118,551 is often used in research to understand the function of this receptor subtype. It has been used in studies investigating the role of the β2 receptor in the heart, lungs, and other tissues.
Potential Therapeutic Uses[edit | edit source]
In animal studies, ICI-118,551 has been found to increase the contractility of the heart. This suggests it could potentially be used to treat heart failure. However, further research is needed to confirm this potential use and to understand the safety and efficacy of ICI-118,551 in humans.
See Also[edit | edit source]
References[edit | edit source]
| ICI-118,551 Resources | |
|---|---|
|
 |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
