IGHG3

Ideogram human chromosome 14

IGHG3

IGHG3 is a gene that encodes a protein known as immunoglobulin heavy constant gamma 3. This protein is a component of the antibodies produced by the immune system in response to foreign substances. The IGHG3 gene is located on chromosome 14 in humans.

Structure

The IGHG3 gene consists of multiple exons that are transcribed into messenger RNA (mRNA) and translated into the immunoglobulin heavy constant gamma 3 protein. This protein plays a crucial role in the immune response by binding to antigens and marking them for destruction by other immune cells.

Function

The primary function of the immunoglobulin heavy constant gamma 3 protein is to facilitate the recognition and neutralization of pathogens such as bacteria and viruses. It does this by binding to specific antigens and triggering immune responses that help eliminate the invading microorganisms.

Clinical Significance

Mutations or dysregulation of the IGHG3 gene can lead to various immune disorders, including autoimmune diseases and immunodeficiency syndromes. Understanding the role of IGHG3 in the immune system is essential for developing targeted therapies for these conditions.

Research

Research on the IGHG3 gene and its protein product is ongoing, with scientists investigating its role in different aspects of the immune response. Studies aim to elucidate the mechanisms by which IGHG3 contributes to immunity and how its dysregulation can result in disease.

See also

• Immunoglobulin
• Antigen
• Immune system
• Chromosome 14