IL17E

IL17E‏‎, also known as Interleukin 17E, is a protein that in humans is encoded by the IL17E gene. It is a member of the Interleukin-17 family of proteins, which are involved in immune and inflammatory responses.

Function

IL17E is a pro-inflammatory cytokine that can induce local inflammation by triggering the release of pro-inflammatory and pro-angiogenic factors from various cell types. It is produced by Th2 cells, a type of T cell, and is involved in the regulation of immune responses, particularly in the context of allergic reactions.

Clinical significance

Due to its role in inflammation, IL17E has been implicated in a number of diseases, including asthma, allergic rhinitis, and atopic dermatitis. It has also been suggested as a potential therapeutic target for these conditions.

Research

Research into IL17E has focused on its role in immune responses and inflammation, as well as its potential as a therapeutic target. Studies have shown that blocking the action of IL17E can reduce inflammation and improve symptoms in models of asthma and allergic rhinitis.

See also

• Interleukin 17
• Interleukin-17 family
• Cytokine
• Inflammation

References

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