Imiloxan
Imiloxan is a pharmacological agent that is classified as an alpha-adrenergic antagonist. It is primarily used in scientific research to study the adrenergic system and its role in various physiological and pathological processes.
Pharmacology[edit | edit source]
Imiloxan is a selective alpha-2 adrenergic receptor antagonist. The alpha-2 adrenergic receptors are a subtype of adrenergic receptors, which are a group of G protein-coupled receptors that are targets for the catecholamines, especially norepinephrine and epinephrine. By blocking the action of these receptors, Imiloxan can increase the release of norepinephrine and other neurotransmitters, leading to increased neuronal activity.
Uses[edit | edit source]
Imiloxan is primarily used in neuroscience research to study the role of the adrenergic system in various physiological and pathological processes. For example, it has been used to investigate the role of the adrenergic system in anxiety and depression, cardiovascular disease, and neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease.
Side Effects[edit | edit source]
As with any pharmacological agent, Imiloxan can have side effects. These can include hypertension (high blood pressure), tachycardia (rapid heart rate), and arrhythmias (irregular heart rhythms). However, these side effects are generally rare and are more likely to occur with higher doses.
See Also[edit | edit source]
- Adrenergic antagonist
- Alpha-2 adrenergic receptor
- G protein-coupled receptor
- Norepinephrine
- Epinephrine
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