Immunoglobulin e
Immunoglobulin E (IgE) is a type of antibody (or immunoglobulin (Ig) that has only been found in mammals. It plays an essential role in the body's immune system. IgE has been associated with various allergic diseases including asthma, allergic rhinitis, and atopic dermatitis.
Structure[edit | edit source]
IgE's main function is immunity to parasites such as parasitic worms like Schistosoma spp, Trichinella spiralis, and Fasciola hepatica. IgE may also be important during immune defense against certain protozoan parasites such as Plasmodium falciparum.
Function[edit | edit source]
IgE also plays a pivotal role in responses to allergens, such as: food, pollen, and medications. Functions of IgE include antigen recognition and binding, regulation of immune response, and prevention of disease by attacking invading pathogens.
Clinical significance[edit | edit source]
High IgE levels can be a result of a parasitic infection or can be associated with different types of tumors. IgE also plays a significant role in allergic reactions. In allergic individuals, an allergen induces the production of IgE antibodies that can bind to Mast cells and basophils in the body.
See also[edit | edit source]
References[edit | edit source]
| Immunoglobulin e Resources | |
|---|---|
|
 |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
