Immunosuppressive therapy

From WikiMD's Food, Medicine & Wellness Encyclopedia

Immunosuppressive therapy is a form of medical treatment that reduces the body's immune response. This type of therapy is often used to prevent the body from rejecting a transplanted organ, and it is also used in the treatment of autoimmune diseases or diseases that are most likely of autoimmune origin.

Overview[edit | edit source]

Immunosuppressive therapy involves the administration of drugs that suppress the immune system. These drugs, known as immunosuppressants, can be divided into two categories: induction drugs, which are used at the time of transplantation, and maintenance drugs, which are used for the long-term.

Indications[edit | edit source]

Immunosuppressive therapy is indicated in the following situations:

  • Organ transplantation: To prevent the body from rejecting a transplanted organ.
  • Autoimmune diseases: To reduce the body's immune response against its own cells and tissues.
  • Certain other conditions: Such as some forms of anemia, neutropenia, and thrombocytopenia.

Types of Immunosuppressants[edit | edit source]

There are several types of immunosuppressants used in immunosuppressive therapy. These include:

Side Effects[edit | edit source]

Like all medications, immunosuppressants can cause side effects. These may include:

  • Increased susceptibility to infections
  • Increased risk of certain types of cancer
  • Bone marrow suppression
  • Liver and kidney damage
  • High blood pressure
  • High cholesterol levels
  • Weight gain
  • Diabetes
  • Gastrointestinal problems

See Also[edit | edit source]

References[edit | edit source]

Immunosuppressive therapy Resources
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Contributors: Bonnu, Prab R. Tumpati, MD