Immunosuppressive therapy
Immunosuppressive therapy is a form of medical treatment that reduces the body's immune response. This type of therapy is often used to prevent the body from rejecting a transplanted organ, and it is also used in the treatment of autoimmune diseases or diseases that are most likely of autoimmune origin.
Overview[edit | edit source]
Immunosuppressive therapy involves the administration of drugs that suppress the immune system. These drugs, known as immunosuppressants, can be divided into two categories: induction drugs, which are used at the time of transplantation, and maintenance drugs, which are used for the long-term.
Indications[edit | edit source]
Immunosuppressive therapy is indicated in the following situations:
- Organ transplantation: To prevent the body from rejecting a transplanted organ.
- Autoimmune diseases: To reduce the body's immune response against its own cells and tissues.
- Certain other conditions: Such as some forms of anemia, neutropenia, and thrombocytopenia.
Types of Immunosuppressants[edit | edit source]
There are several types of immunosuppressants used in immunosuppressive therapy. These include:
- Corticosteroids
- Calcineurin inhibitors
- mTOR inhibitors
- Antiproliferative agents
- Monoclonal antibodies
- Polyclonal antibodies
Side Effects[edit | edit source]
Like all medications, immunosuppressants can cause side effects. These may include:
- Increased susceptibility to infections
- Increased risk of certain types of cancer
- Bone marrow suppression
- Liver and kidney damage
- High blood pressure
- High cholesterol levels
- Weight gain
- Diabetes
- Gastrointestinal problems
See Also[edit | edit source]
References[edit | edit source]
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