Monoclonal antibodies

Monoclonal antibodies is an antibody that is produced in the laboratory so that it will react with only one specific foreign protein; used to help diagnose certain kinds of cancer

List of monoclonal antibodies

• Bezlotoxumab trade name (Zinplava), is a human monoclonal antibody that targets Clostridium difficile used in the treatment of Clostridium difficile colitis.
• Cosfroviximab trade name (ZMapp), is a chimeric monoclonal antibody that targets ebolavirus glycoprotein used in the treatment of Ebola virus.
• Ibritumomab tiuxetan trade name (Zevalin), is a mouse monoclonal antibody that targets CD20 used in the treatment of non-Hodgkin's lymphoma.
• Daclizumab trade name (Zenapax), is a humanized monoclonal antibody that targets CD25 (α chain of IL-2 receptor) used in the treatment of prevention of organ transplant rejections, multiple sclerosis.
• Ipilimumab trade name (Yervoy), is a human monoclonal antibody that targets CD152 used in the treatment of melanoma.
• Omalizumab trade name (Xolair), is a humanized monoclonal antibody that targets IgE Fc region used in the treatment of allergic asthma.
• Bermekimab trade name (Xilonix), is a human monoclonal antibody that targets IL1A used in the treatment of colorectal cancer.
• Eptinezumab trade name (Vyepti), is a humanized monoclonal antibody that targets calcitonin gene-related peptide used in the treatment of migraine.
• Oportuzumab monatox trade name (Vicinium), is a humanized (scFv), is a EpCAM used in the treatment of bladder cancer.
• Nofetumomab merpentan, (Verluma), is a mouse (Fab), is a ? used in the treatment of cancer (diagnosis).
• Panitumumab trade name (Vectibix), is a human monoclonal antibody that targets epidermal growth factor receptor (EGFR) used in the treatment of colorectal cancer.
• Racotumomab trade name (Vaxira), is a mouse monoclonal antibody that targets NGNA ganglioside used in the treatment of non-small cell lung cancer.
• Inebilizumab trade name (Uplizna), is a humanized monoclonal antibody that targets CD19 used in the treatment of cancer, systemic sclerosis, multiple sclerosis.
• Dinutuximab trade name (Unituxin), is a chimeric monoclonal antibody that targets GD2 ganglioside used in the treatment of neuroblastoma.
• Ravulizumab trade name (Ultomiris), is a humanized monoclonal antibody that targets C5 used in the treatment of paroxysmal nocturnal hemoglobinuria, atypical hemolytic uremic syndrome.
• Natalizumab trade name (Tysabri), is a humanized monoclonal antibody that targets integrin α4 used in the treatment of multiple sclerosis, Crohn's disease.
• Ibalizumab trade name (Trogarzo), is a humanized monoclonal antibody that targets CD4 used in the treatment of HIV infection.
• Sacituzumab govitecan trade name (Trodelvy), is a humanized monoclonal antibody that targets TROP-2 used in the treatment of triple-negative breast cancer.
• Guselkumab trade name (Tremfya), is a human monoclonal antibody that targets IL23 used in the treatment of psoriasis.
• Pemtumomab trade name (Theragyn), is a mousemonoclonal antibody that targets MUC1 used in the treatment of cancer.
• Teprotumumab trade name (Tepezza), is a human monoclonal antibody that targets IGF-1 receptor (CD221) used in the treatment of thyroid eye disease.
• Atezolizumab trade name (Tecentriq), is a humanized monoclonal antibody that targets PD-L1 used in the treatment of cancer.
• Ixekizumab trade name (Taltz), is a humanized monoclonal antibody that targets IL 17A used in the treatment of autoimmune diseases.
• Lanadelumab trade name (Takhzyro), is a human monoclonal antibody that targets kallikrein used in the treatment of angioedema.
• Tamtuvetmab trade name (Tactress), is a veterinary monoclonal antibody that targets CD52.
• Palivizumab trade name (Synagis, Abbosynagis), is a humanized monoclonal antibody that targets F protein of respiratory syncytial virus used in the treatment of respiratory syncytial virus (prevention).
• Siltuximab trade name (Sylvant), is a chimeric monoclonal antibody that targets IL-6 used in the treatment of cancer.
• Ustekinumab trade name (Stelara), is a human monoclonal antibody that targets IL-12, IL-23 used in the treatment of multiple sclerosis, psoriasis, psoriatic arthritis.
• Eculizumab trade name (Soliris), is a humanized monoclonal antibody that targets C5 used in the treatment of paroxysmal nocturnal hemoglobinuria, atypical hemolytic uremic syndrome.
• Risankizumab trade name (Skyrizi), is a humanized monoclonal antibody that targets IL23A used in the treatment of Crohn's disease, psoriasis, psoriatic arthritis, and asthma.
• Basiliximab trade name (Simulect), is a chimeric monoclonal antibody that targets CD25 (α chain of IL-2 receptor) used in the treatment of prevention of organ transplant rejections.
• Golimumab trade name (Simponi), is a human monoclonal antibody that targets TNF-α used in the treatment of rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis.
• Brodalumab trade name (Siliq), is a human monoclonal antibody that targets IL-17 used in the treatment of Plaque psoriasis.
• Besilesomab trade name (Scintimun), is a mouse monoclonal antibody that targets Carcinoembryonic antigen (CEA)-related antigen used in the treatment of inflammatory lesions and metastases (detection).
• Isatuximab trade name (Sarclisa), is a chimeric monoclonal antibody that targets CD38 used in the treatment of multiple myeloma.
• Ertumaxomab trade name (Rexomun), is a rat/mouse hybrid (3funct), is a HER2/neu, CD3 used in the treatment of breast cancer etc..
• Evolocumab trade name (Repatha), is a human monoclonal antibody that targets PCSK9 used in the treatment of hypercholesterolemia.
• Abciximab trade name (ReoPro), is a chimeric (Fab), is a CD41 (integrin alpha-IIb) used in the treatment of platelet aggregation inhibitor.
• Girentuximab trade name (Rencarex), is a chimeric monoclonal antibody that targets carbonic anhydrase 9 (CA-IX) used in the treatment of clear cell renal cell carcinoma.
• Catumaxomab trade name (Removab), is a rat/mouse hybrid (3funct), is a EpCAM, CD3 used in the treatment of ovarian cancer, malignant ascites, gastric cancer.
• Infliximab trade name (Remicade), is a chimeric monoclonal antibody that targets TNF-α used in the treatment of rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, psoriasis, Crohn's disease, ulcerative colitis.
• Efalizumab trade name (Raptiva), is a humanized monoclonal antibody that targets LFA-1 (CD11a) used in the treatment of psoriasis (blocks T-cell migration).
• Rmab trade name (RabiShield), is a humanmonoclonal antibody that targets rabies virus G glycoprotein used in the treatment of post-exposure prophylaxis of rabies.
• Dinutuximab beta trade name (Qarziba), is a chimeric monoclonal antibody that targets GD2 ganglioside used in the treatment of neuroblastoma.
• Capromab trade name (Prostascint), is a mouse monoclonal antibody that targets Glutamate carboxypeptidase II used in the treatment of prostate cancer (detection).
• Denosumab trade name (Prolia), is a human monoclonal antibody that targets RANKL used in the treatment of osteoporosis, bone metastases etc..
• Idarucizumab trade name (Praxbind), is a humanized monoclonal antibody that targets dabigatran used in the treatment of reversal of anticoagulant effects of dabigatran.
• Alirocumab trade name (Praluent), is a human monoclonal antibody that targets PCSK9 used in the treatment of hypercholesterolemia.
• Mogamulizumab trade name (Poteligeo), is a humanized monoclonal antibody that targets CCR4 used in the treatment of adult T-cell leukemia/lymphoma.
• Necitumumab trade name (Portrazza), is a human monoclonal antibody that targets Epidermal growth factor receptor (EGFR) used in the treatment of non-small cell lung carcinoma.
• Polatuzumab vedotin trade name (Polivy), is a humanized monoclonal antibody that targets CD79B used in the treatment of diffuse large B-cell lymphoma.
• Pertuzumab trade name (Perjeta), is a humanized monoclonal antibody that targets HER2/neu used in the treatment of cancer.
• Edrecolomab trade name (Panorex), is a mouse monoclonal antibody that targets EpCAM used in the treatment of colorectal carcinoma.
• Enfortumab vedotin trade name (Padcev), is a human monoclonal antibody that targets nectin-4 used in the treatment of urothelial cancer.
• Oregovomab trade name (OvaRex), is a mouse monoclonal antibody that targets CA-125 used in the treatment of ovarian cancer.
• Muromonab-CD3 trade name (Orthoclone OKT3), is a mouse monoclonal antibody that targets CD3 used in the treatment of prevention of organ transplant rejections.
• Nivolumab trade name (Opdivo), is a human monoclonal antibody that targets PD-1 used in the treatment of cancer.
• Ocrelizumab trade name (Ocrevus), is a humanized monoclonal antibody that targets CD20 used in the treatment of multiple sclerosis.
• Visilizumab trade name (Nuvion), is a humanized monoclonal antibody that targets CD3 used in the treatment of Crohn's disease, ulcerative colitis.
• Motavizumab trade name (Numax), is a humanized monoclonal antibody that targets respiratory syncytial virus used in the treatment of respiratory syncytial virus (prevention).
• Fanolesomab trade name (NeutroSpec), is a mouse monoclonal antibody that targets CD15 used in the treatment of appendicitis (diagnosis).
• Imciromab trade name (Myoscint), is a mouse monoclonal antibody that targets cardiac myosin used in the treatment of cardiac imaging.
• Gemtuzumab ozogamicin trade name (Mylotarg), is a humanized monoclonal antibody that targets CD33 used in the treatment of acute myelogenous leukemia.
• Efungumab trade name (Mycograb), is a human (scFv), is a Hsp90 used in the treatment of invasive Candida infection.
• Tafasitamab trade name (Monjuvi), is a humanized (from mouse) monoclonal antibody that targets CD19 used in the treatment of relapsed or refractory diffuse large B-cell lymphoma.
• Margetuximab trade name (Margenza8)) is a humanized monoclonal antibody that targets HER2 used in the treatment of breast cancer.
• Rituximab trade name (MabThera, Rituxan), is a chimeric monoclonal antibody that targets CD20 used in the treatment of lymphomas, leukemias, some autoimmune disorders.
• Bectumomab trade name (LymphoScan), is a mouse (Fab'), is a CD22 used in the treatment of non-Hodgkin's lymphoma (detection).
• FBTA057 trade name (Lymphomun), is a rat/mouse hybrid (3funct), is a CD20 used in the treatment of chronic lymphocytic leukaemia.
• Moxetumomab pasudotox trade name (Lumoxiti), is a mouse monoclonal antibody that targets CD22 used in the treatment of hairy cell leukemia.
• Ranibizumab trade name (Lucentis), is a humanized (Fab), is a VEGF-A used in the treatment of macular degeneration (wet form).
• Cemiplimab trade name (Libtayo), is a human monoclonal antibody that targets PDCD1 used in the treatment of cutaneous squamous cell carcinoma.
• Sulesomab trade name (LeukoScan), is a mouse (Fab'), is a NCA-90 (granulocyte antigen) used in the treatment of osteomyelitis (imaging).
• Rovelizumab trade name (LeukArrest), is a humanized monoclonal antibody that targets CD11, CD18 used in the treatment of haemorrhagic shock etc..
• Alemtuzumab trade name (Lemtrada, Campath), is a humanized monoclonal antibody that targets CD52 used in the treatment of multiple sclerosis.
• Olaratumab trade name (Lartruvo), is a human monoclonal antibody that targets PDGF-R α used in the treatment of cancer.
• Pembrolizumab trade name (Keytruda), is a humanized monoclonal antibody that targets PD-1 used in the treatment of melanoma and other cancers.
• Sarilumab trade name (Kevzara), is a human monoclonal antibody that targets IL6 used in the treatment of rheumatoid arthritis, ankylosing spondylitis.
• Trastuzumab duocarmazine trade name (Kadcyla), is a humanized monoclonal antibody that targets HER2/neu used in the treatment of breast cancer.
• Trastuzumab emtansine trade name (Kadcyla), is a humanized monoclonal antibody that targets HER2/neu used in the treatment of breast cancer.
• Atoltivimab/maftivimab/odesivimab trade name (Inmazeb), is a human (mab), is a treatment of Zaire ebolavirus (Ebola virus).
• Igovomab trade name (Indimacis-125), is a mouse (F(ab')2), is a CA-125 used in the treatment of ovarian cancer (diagnosis).
• Durvalumab trade name (Imfinzi), is a human monoclonal antibody that targets PD-L1 used in the treatment of cancer.
• Tildrakizumab trade name (Ilumya), is a humanized monoclonal antibody that targets IL23 used in the treatment of immunologically mediated inflammatory disorders.
• Canakinumab trade name (Ilaris), is a human monoclonal antibody that targets IL-1 used in the treatment of cryopyrin-associated periodic syndrome.
• Altumomab pentetate trade name (Hybri-ceaker), is a mouse monoclonal antibody that targets Carcinoembryonic antigen (CEA) used in the treatment of colorectal cancer (diagnosis).
• Fontolizumab trade name (HuZAF), is a humanized monoclonal antibody that targets IFN-γ used in the treatment of Crohn's disease etc..
• Adalimumab trade name (Humira), is a human monoclonal antibody that targets TNF-α used in the treatment of rheumatoid arthritis, Crohn's disease, plaque psoriasis, psoriatic arthritis, ankylosing spondylitis, juvenile idiopathic arthritis, hemolytic disease of the newborn.
• Votumumab trade name (HumaSPECT), is a human monoclonal antibody that targets tumor antigen CTAA16.88 used in the treatment of colorectal tumors.
• Clivatuzumab tetraxetan trade name (hPAM4-Cide), is a humanized monoclonal antibody that targets MUC1 used in the treatment of pancreatic cancer.
• Trastuzumab trade name (Herceptin), is a humanized monoclonal antibody that targets HER2/neu used in the treatment of breast cancer.
• Emicizumab trade name (Hemlibra), is a humanized monoclonal antibody that targets activated F9, F10 used in the treatment of haemophilia A.
• Obinutuzumab trade name (Gazyva), is a humanized monoclonal antibody that targets CD20 used in the treatment of chronic lymphatic leukemia.
• Emapalumab trade name (Gamifant), is a human monoclonal antibody that targets interferon gamma used in the treatment of hemophagocytic lymphohistiocytosis.
• Biciromab trade name (FibriScint), is a mouse (Fab'), is a fibrin II, beta chain used in the treatment of thromboembolism (diagnosis).
• Benralizumab trade name (Fasenra), is a humanized monoclonal antibody that targets CD125 used in the treatment of asthma.
• Romosozumab trade name (Evenity), is a humanized monoclonal antibody that targets sclerostin used in the treatment of osteoporosis.
• Cetuximab trade name (Erbitux), is a chimeric monoclonal antibody that targets Epidermal growth factor receptor (EGFR) used in the treatment of metastatic colorectal cancer and head and neck cancer.
• Vedolizumab trade name (Entyvio), is a humanized monoclonal antibody that targets integrin α4β7 used in the treatment of Crohn's disease, ulcerative colitis.
• Satralizumab trade name (Enspryng), is a humanized monoclonal antibody that targets IL6 receptor used in the treatment of neuromyelitis optica.
• Elotuzumab trade name (Empliciti), is a humanized monoclonal antibody that targets SLAMF7 used in the treatment of multiple myeloma.
• Galcanezumab trade name (Emgality), is a humanized monoclonal antibody that targets calcitonin used in the treatment of migraine.
• TRBS07 trade name (Ektomonoclonal antibody that targets | 3funct), is a GD2 ganglioside used in the treatment of melanoma.
• Netakimab trade name (Efleira), is a chimeric monoclonal antibody that targets interleukin 17A used in the treatment of plaque psoriasis.
• Ansuvimab trade name (Ebanga), is a human monoclonal antibody that targets Ebola virus glycoprotein used in the treatment of treatment of Zaire ebolavirus (Ebola virus).
• Dupilumab trade name (Dupixent), is a human monoclonal antibody that targets IL-4Rα used in the treatment of atopic dermatitis, asthma, nasal polyps.
• Daratumumab trade name (Darzalex), is a human monoclonal antibody that targets CD38 used in the treatment of multiple myeloma.
• Naxitamab trade name (Danyelza), is a humanizedmonoclonal antibody that targets c-Met used in the treatment of high-risk neuroblastoma and refractory osteomedullary disease.
• Lokivetmab trade name (Cytopoint7)) is a veterinary monoclonal antibody that targets Canis lupus familiaris IL31 used in the treatment of clinical signs of atopic dermatitis in dogs.
• Ramucirumab]] (Cyramza), is a human monoclonal antibody that targets VEGFR2 used in the treatment of solid tumors.
• Burosumab trade name (Crysvita), is a human monoclonal antibody that targets FGF 23 used in the treatment of X-linked hypophosphatemia.
• Secukinumab trade name (Cosentyx), is a human monoclonal antibody that targets IL 17A used in the treatment of uveitis, rheumatoid arthritis psoriasis.
• Reslizumab trade name (Cinqair), is a humanized monoclonal antibody that targets IL-5 used in the treatment of inflammations of the airways, skin and gastrointestinal tract.
• Certolizumab pegol trade name (Cimzia), is a humanized (Fab'), is a TNF-α used in the treatment of Crohn's disease, rheumatoid arthritis, axial spondyloarthritis, psoriasis arthritis.
• Arcitumomab trade name (CEA-Scan), is a mouse (Fab'), is a Carcinoembryonic antigen (CEA) used in the treatment of gastrointestinal cancers (diagnosis).
• Labetuzumab trade name (CEA-Cide), is a humanized monoclonal antibody that targets Carcinoembryonic antigen (CEA) used in the treatment of colorectal cancer.
• Caplacizumab trade name (Cablivi), is a humanized (sdAb), is a VWF used in the treatment of thrombotic thrombocytopenic purpura, thrombosis.
• Mepolizumab trade name (Bosatria), is a humanized monoclonal antibody that targets IL-5 used in the treatment of asthma and white blood cell diseases.
• Blontuvetmab trade name (Blontress), is a veterinary monoclonal antibody that targets CD20.
• Blinatumomab trade name (Blincyto), is a mouse (BiTE), is a CD19 used in the treatment of pre-B Acute lymphoblastic leukemia (ALL) (CD19+).
• Belantamab mafodotin trade name (Blenrep), is a humanized monoclonal antibody that targets B-cell maturation antigen (BCMA) used in the treatment of relapsed or refractory multiple myeloma.
• Nimotuzumab trade name (BioMab-EGFR, Theracim, Theraloc), is a humanized monoclonal antibody that targets epidermal growth factor receptor (EGFR) used in the treatment of squamous cell carcinoma, head and neck cancer, nasopharyngeal cancer, glioma.
• Tositumomab trade name (Bexxar), is a mousemonoclonal antibody that targets CD20 used in the treatment of follicular lymphoma.
• Inotuzumab ozogamicin trade name (Besponsa), is a humanized monoclonal antibody that targets CD22 used in the treatment of Acute lymphoblastic leukemia (ALL).
• Brolucizumab trade name (Beovu), is a humanized (scFv), is a vascular endothelial growth factor A (VEGFA) used in the treatment of wet age-related macular degeneration.
• Belimumab trade name (Benlysta), is a human monoclonal antibody that targets B-cell activating factor (BAFF) used in the treatment of systemic lupus erythematosus without renal or CNS involvement.
• Avelumab trade name (Bavencio), is a human monoclonal antibody that targets PD-L1 used in the treatment of cancer.
• Bevacizumab trade name (Avastin), is a humanized monoclonal antibody that targets VEGF-A used in the treatment of metastatic cancer, retinopathy of prematurity.
• Tefibazumab trade name (Aurexis), is a humanized monoclonal antibody that targets clumping factor A used in the treatment of Staphylococcus aureus infection.
• Ofatumumab trade name (Arzerra, Kesimpta4)) is a human monoclonal antibody that targets CD20 used in the treatment of chronic lymphocytic leukemia.
• multiple sclerosis.
• Ruplizumab trade name (Antova), is a humanized monoclonal antibody that targets CD154 (CD40L) used in the treatment of rheumatic diseases.
• Obiltoxaximab trade name (Anthim), is a chimeric monoclonal antibody that targets Bacillus anthracis anthrax used in the treatment of Bacillus anthracis spores.
• Itolizumab trade name (Alzumonoclonal antibody that targets humanized monoclonal antibody that targets CD6 used in the treatment of psoriasis.
• Fremanezumab trade name (Ajovy), is a humanized monoclonal antibody that targets calcitonin gene-related peptide alpha used in the treatment of migraine and cluster headache.
• Erenumab trade name (Aimovig), is a human monoclonal antibody that targets calcitonin gene-related peptide receptor (CGRP) used in the treatment of migraine.
• Tacatuzumab tetraxetan trade name (AFP-Cide), is a humanized monoclonal antibody that targets alpha-fetoprotein used in the treatment of cancer.
• Brentuximab vedotin trade name (Adcentris), is a chimeric monoclonal antibody that targets CD30 (TNFRSF8) used in the treatment of Hodgkin's lymphoma.
• anaplastic large-cell lymphoma.
• Crizanlizumab trade name (Adakveo), is a humanized monoclonal antibody that targets selectin P used in the treatment of sickle-cell disease.
• Tocilizumab trade name (Actemra, RoActemra), is a humanized monoclonal antibody that targets IL-6 receptor used in the treatment of rheumatoid arthritis.
• Etaracizumab trade name (Abegrin), is a humanized monoclonal antibody that targets integrin αvβ3 used in the treatment of melanoma, prostate cancer, ovarian cancer etc..
• 3F8 is a mouse monoclonal antibody that targets GD2 ganglioside used in the treatment of neuroblastoma.
• 8H, is a mouse monoclonal antibody that targets B7-H3 used in the treatment of neuroblastoma, sarcoma, metastatic brain cancers.
• Abagovomab, is a mouse monoclonal antibody that targets CA-125 (imitation) used in the treatment of ovarian cancer.
• Abituzumab, is a humanized monoclonal antibody that targets CD51 used in the treatment of cancer.
• Abrezekimab, is a humanized (Fab), is a interleukin 13.
• Abrilumab, is a human monoclonal antibody that targets integrin α4β7 used in the treatment of inflammatory bowel disease, ulcerative colitis, Crohn's disease.
• Actoxumab, is a human monoclonal antibody that targets Clostridium difficile used in the treatment of Clostridium difficile colitis.
• Adecatumumab, is a human monoclonal antibody that targets EpCAM used in the treatment of prostate and breast cancer.
• Aducanumab, is a human monoclonal antibody that targets beta-amyloid used in the treatment of Alzheimer's disease.
• Afasevikumab, is a human monoclonal antibody that targets IL17A and IL17F used in the treatment of multiple sclerosis.
• Afelimomab, is a mouse (F(ab')2), is a TNF-α used in the treatment of sepsis.
• Alacizumab pegol, is a humanized (F(ab')2), is a VEGFR2 used in the treatment of cancer.
• Amatuximab, is a chimeric monoclonal antibody that targets mesothelin used in the treatment of cancer.
• Amivantamab is a human (bsmonoclonal antibody that targets Epidermal growth factor receptor (EGFR), cMet used in the treatment of non-small cell lung cancer.
• Anatumomab mafenatox, is a mouse (Fab), is a Tumor-associated glycoprotein 72 (TAG-72) used in the treatment of non-small cell lung cancer.
• Andecaliximab, is a chimeric monoclonal antibody that targets gelatinase B used in the treatment of gastric cancer or gastroesophageal junction adenocarcinoma.
• Anetumab ravtansine, is a human monoclonal antibody that targets mesothelin (MSLN) used in the treatment of cancer.
• Anifrolumab, is a human monoclonal antibody that targets interferon α/β receptor used in the treatment of systemic lupus erythematosus.
• Anrukinzumab1 trade name IMA-63, is a humanized monoclonal antibody that targets IL-13 used in the treatment of asthma.
• Apolizumab, is a humanized monoclonal antibody that targets HLA-DR ? used in the treatment of hematological cancers.
• Aprutumab ixadotin, is a human monoclonal antibody that targets FGFR2.
• Ascrinvacumab, is a human monoclonal antibody that targets activin receptor-like kinase 1 used in the treatment of cancer.
• Aselizumab, is a humanized monoclonal antibody that targets L-selectin (CD62L) used in the treatment of severely injured patients.
• Atidortoxumab, is a human monoclonal antibody that targets Staphylococcus aureus alpha toxin.
• Atinumab, is a human monoclonal antibody that targets RTN4.
• Atoltivimab is a human (mab), is a part of Atoltivimab/maftivimab/odesivimab for treatment of Zaire ebolavirus (Ebola virus).
• Atorolimumab, is a human monoclonal antibody that targets Rhesus factor used in the treatment of hemolytic disease of the newborn(citation needed).
• Azintuxizumab vedotin, is a chimeric/humanized monoclonal antibody that targets CD319 used in the treatment of cancer.
• Bapineuzumab, is a humanized monoclonal antibody that targets beta amyloid used in the treatment of Alzheimer's disease.
• Bavituximab, is a chimeric monoclonal antibody that targets phosphatidylserine used in the treatment of cancer, viral infections.
• BCD-100 is a humanmonoclonal antibody that targets PD-1 used in the treatment of melanoma.
• Begelomab, is a mouse monoclonal antibody that targets DPP4.
• Bemarituzumab, is a humanized monoclonal antibody that targets FGFR2 used in the treatment of gastric cancer or gastroesophageal junction adenocarcinoma.
• Berlimatoxumab, is a human monoclonal antibody that targets Staphylococcus aureus bi-component leukocidin.
• Bersanlimab, is a human monoclonal antibody that targets ICAM-1.
• Bertilimumab, is a human monoclonal antibody that targets CCL11 (eotaxin-1) used in the treatment of severe allergic disorders.
• Bimagrumab, is a human monoclonal antibody that targets ACVR2B used in the treatment of myostatin inhibitor.
• Bimekizumab, is a humanized monoclonal antibody that targets IL 17A and IL 17F used in the treatment of ankylosing spondylitis, psoriasis.
• Birtamimab is a chimeric monoclonal antibody that targets serum amyloid A protein used in the treatment of amyloidosis.
• Bivatuzumab, is a humanized monoclonal antibody that targets CD44 v6 used in the treatment of squamous cell carcinoma.
• Bleselumab, is a human monoclonal antibody that targets CD40 used in the treatment of organ transplant rejection.
• Blosozumab, is a humanized monoclonal antibody that targets SOST used in the treatment of osteoporosis.
• Bococizumab, is a humanized monoclonal antibody that targets PCSK9 used in the treatment of dyslipidemia.
• Brazikumab, is a human monoclonal antibody that targets IL23 used in the treatment of Crohn's disease.
• Briakinumab, is a human monoclonal antibody that targets IL-12, IL-23 used in the treatment of psoriasis, rheumatoid arthritis, inflammatory bowel diseases, multiple sclerosis.
• Brontictuzumab, is a humanized monoclonal antibody that targets Notch 1 used in the treatment of cancer.
• Cabiralizumab, is a humanized monoclonal antibody that targets CSF1R used in the treatment of metastatic pancreatic cancer.
• Camidanlumab tesirine, is a human monoclonal antibody that targets CD25 (α chain of IL-2 receptor) used in the treatment of B-cell Hodgkin's lymphoma, non-Hodgkin lymphoma, acute lymphoblastic leukemia, acute myeloid leukemia.
• Camrelizumab, is a humanized monoclonal antibody that targets PD-1 used in the treatment of hepatocellular carcinoma.
• Cantuzumab mertansine, is a humanized monoclonal antibody that targets CanAg (a glycoform of MUC1) used in the treatment of colorectal cancer etc..
• Cantuzumab ravtansine, is a humanized monoclonal antibody that targets CanAg (a glycoform of MUC1) used in the treatment of cancers.
• Casirivimab is a human monoclonal antibody that targets spike protein receptor binding domain (RBD) of SARS-CoV-2 used in the treatment of COVID-19.
• Carlumab, is a human monoclonal antibody that targets MCP-1 used in the treatment of oncology/immune indications.
• Carotuximab, is a chimeric monoclonal antibody that targets endoglin used in the treatment of angiosarcoma.
• cBR96-doxorubicin immunoconjugate is a humanized monoclonal antibody that targets Lewis-Y antigen used in the treatment of cancer.
• Cedelizumab, is a humanized monoclonal antibody that targets CD4 used in the treatment of prevention of organ transplant rejections, treatment of autoimmune diseases.
• Cergutuzumab amunaleukin, is a humanized monoclonal antibody that targets IL2 used in the treatment of cancer.
• Cetrelimab, is a human monoclonal antibody that targets PD-1 used in the treatment of cancer.
• Cibisatamab, is a humanized monoclonal antibody that targets CEACAM5 used in the treatment of cancer.
• Cirmtuzumab, is a humanizedmonoclonal antibody that targets ROR1 used in the treatment of chronic lymphocytic leukemia.
• Citatuzumab bogatox, is a humanized (Fab), is a EpCAM used in the treatment of ovarian cancer and other solid tumors.
• Cixutumumab, is a human monoclonal antibody that targets IGF-1 receptor (CD221) used in the treatment of solid tumors.
• Clazakizumab, is a humanized monoclonal antibody that targets Interleukin 6 (IL-6) used in the treatment of rheumatoid arthritis.
• Clenoliximab, is a chimeric monoclonal antibody that targets CD4 used in the treatment of rheumatoid arthritis.
• Codrituzumab, is a humanized monoclonal antibody that targets glypican 3 used in the treatment of cancer.
• Cofetuzumab pelidotin, is a humanized monoclonal antibody that targets PTK7 used in the treatment of cancer.
• Coltuximab ravtansine, is a chimeric monoclonal antibody that targets CD19 used in the treatment of cancer.
• Conatumumab, is a human monoclonal antibody that targets TRAIL-R2 used in the treatment of cancer.
• Concizumab, is a humanized monoclonal antibody that targets tissue factor pathway inhibitor (TFPI) used in the treatment of bleeding.
• Crenezumab, is a humanized monoclonal antibody that targets 1-40-β-amyloid used in the treatment of Alzheimer's disease.
• Crotedumab, is a human monoclonal antibody that targets glucagon receptor (GCGR) used in the treatment of diabetes.
• CR6261 is a human monoclonal antibody that targets Influenza A hemagglutinin used in the treatment of infectious disease/influenza A.
• Cusatuzumab, is a humanized monoclonal antibody that targets CD70 used in the treatment of cancer.
• Dacetuzumab, is a humanized monoclonal antibody that targets CD40 used in the treatment of hematologic cancers.
• Dalotuzumab is a humanized monoclonal antibody that targets IGF-1 receptor (CD221) used in the treatment of cancer etc..
• Dapirolizumab pegol, is a humanized monoclonal antibody that targets CD154 (CD40L).
• Dectrekumab, is a human monoclonal antibody that targets IL-13.
• Demcizumab is a humanized monoclonal antibody that targets DLL4 used in the treatment of cancer.
• Denintuzumab mafodotin, is a humanized monoclonal antibody that targets CD19 used in the treatment of cancer.
• Depatuxizumab mafodotin, is a chimeric/humanized monoclonal antibody that targets EGFR used in the treatment of glioblastoma.
• Derlotuximab biotin is a chimeric monoclonal antibody that targets histone complex used in the treatment of recurrent glioblastoma multiforme.
• Detumomab is a mouse monoclonal antibody that targets B-lymphoma cell used in the treatment of lymphoma.
• Dezamizumab, is a humanized monoclonal antibody that targets serum amyloid P component.
• Diridavumab is a human monoclonal antibody that targets hemagglutinin used in the treatment of influenza A.
• Domagrozumab, is a humanized monoclonal antibody that targets GDF-8 used in the treatment of Duchenne muscular dystrophy.
• Dorlimomab aritox, is a mouse (F(ab')2), is a ?.
• Dostarlimab, is a humanized monoclonal antibody that targets PCDP1 used in the treatment of cancer.
• Drozitumab is a human monoclonal antibody that targets DR5 used in the treatment of cancer etc..
• DS-8201 is a humanizedmonoclonal antibody that targets HER2 used in the treatment of gastric or gastroesophageal junction adenocarcinoma.
• Duligotuzumab, is a humanized monoclonal antibody that targets ERBB3 (HER3) used in the treatment of testicular cancer.
• Dusigitumab is a human monoclonal antibody that targets ILGF2 used in the treatment of B-cell malignancies.
• Duvortuxizumab, is a chimeric/humanized (scFv), is a CD19, CD3E used in the treatment of cancer.
• Ecromeximab, is a chimeric monoclonal antibody that targets GD3 ganglioside used in the treatment of malignant melanoma.
• Edobacomab is a mouse monoclonal antibody that targets endotoxin used in the treatment of sepsis caused by Gram-negative bacteria.
• Eldelumab, is a human monoclonal antibody that targets interferon gamma-induced protein used in the treatment of Crohn's disease, ulcerative colitis.
• Elezanumab, is a human monoclonal antibody that targets repulsive guidance molecule A (RGMA) used in the treatment of spinal cord injury and multiple sclerosis.
• Elgemtumab, is a human monoclonal antibody that targets ERBB3 (HER3) used in the treatment of cancer.
• Elsilimomab is a mouse monoclonal antibody that targets IL-6.
• Emactuzumab, is a humanized monoclonal antibody that targets CSF1R used in the treatment of cancer.
• Emibetuzumab is a humanized monoclonal antibody that targets hHGFR used in the treatment of cancer.
• Enapotamab vedotin, is a human monoclonal antibody that targets AXL used in the treatment of cancer.
• Enavatuzumab is a humanized monoclonal antibody that targets TWEAK receptor used in the treatment of cancer etc..
• Enlimomab pegol, is a mouse monoclonal antibody that targets ICAM-1 (CD54).
• Enoblituzumab, is a humanized monoclonal antibody that targets CD276 used in the treatment of cancer.
• Enokizumab is a humanized monoclonal antibody that targets IL9 used in the treatment of asthma.
• Enoticumab, is a human monoclonal antibody that targets DLL4.
• Ensituximab is a chimeric monoclonal antibody that targets MUC5AC used in the treatment of cancer.
• Epcoritamab is a human (bsmonoclonal antibody that targets CD3, CD20 used in the treatment of B-cell lymphoma.
• Epitumomab cituxetan, is a mouse monoclonal antibody that targets episialin.
• Epratuzumab is a humanized monoclonal antibody that targets CD22 used in the treatment of cancer, systemic lupus erythematosus (SLE).
• Erlizumab, is a humanized (F(ab')2), is a ITGB2 (CD18) used in the treatment of heart attack, stroke, traumatic shock.
• Etigilimab, is a humanized monoclonal antibody that targets TIGIT.
• Etrolizumab, is a humanized monoclonal antibody that targets integrin β7 used in the treatment of inflammatory bowel disease.
• Evinacumab is a human monoclonal antibody that targets angiopoietin 3 used in the treatment of dyslipidemia.
• Exbivirumab, is a human monoclonal antibody that targets hepatitis B surface antigen used in the treatment of hepatitis B.
• Faralimomab is a mouse monoclonal antibody that targets interferon receptor.
• Faricimab, is a humanized monoclonal antibody that targets VEGF-A and Ang-2 used in the treatment of angiogenesis, ocular vascular diseases.
• Farletuzumab is a humanized monoclonal antibody that targets folate receptor 1 used in the treatment of ovarian cancer.
• Fasinumab is a human monoclonal antibody that targets Nerve growth factor (HNGF) used in the treatment of acute sciatic pain.
• Felvizumab is a humanized monoclonal antibody that targets respiratory syncytial virus used in the treatment of respiratory syncytial virus infection.
• Fezakinumab, is a human monoclonal antibody that targets IL-22 used in the treatment of rheumatoid arthritis, psoriasis.
• Fibatuzumab, is a humanized monoclonal antibody that targets ephrin receptor A3.
• Ficlatuzumab is a humanized monoclonal antibody that targets Hepatocyte growth factor (HGF) used in the treatment of cancer etc..
• Figitumumab is a human monoclonal antibody that targets IGF-1 receptor (CD221) used in the treatment of adrenocortical carcinoma, non-small cell lung carcinoma etc..
• Firivumab, is a human monoclonal antibody that targets influenza A virus hemagglutinin.
• Flanvotumab is a human monoclonal antibody that targets TYRP1 (glycoprotein 75) used in the treatment of melanoma.
• Fletikumab is a human monoclonal antibody that targets IL 20 used in the treatment of rheumatoid arthritis.
• Flotetuzumab, is a humanized (di-scFv), is a IL 3 receptor used in the treatment of hematological malignancies.
• Foralumab, is a human monoclonal antibody that targets CD3 epsilon.
• Foravirumab, is a human monoclonal antibody that targets rabies virus glycoprotein used in the treatment of rabies (prophylaxis).
• Fresolimumab, is a human monoclonal antibody that targets TGF-β used in the treatment of idiopathic pulmonary fibrosis, focal segmental glomerulosclerosis, cancer.
• Frovocimab, is a humanized monoclonal antibody that targets PCSK9 used in the treatment of hypercholesterolemia.
• Frunevetmab, is a veterinary monoclonal antibody that targets nerve growth factor (NGF).
• Fulranumab is a human monoclonal antibody that targets Nerve growth factor (NGF) used in the treatment of pain.
• Futuximab, is a chimeric monoclonal antibody that targets Epidermal growth factor receptor (EGFR) used in the treatment of cancer.
• Galiximab is a chimeric monoclonal antibody that targets CD80 used in the treatment of B-cell lymphoma.
• Gancotamab is a human (scFv), is a HER2/neu used in the treatment of cancer.
• Ganitumab is a human monoclonal antibody that targets IGF-1 receptor (CD221) used in the treatment of cancer.
• Gantenerumab, is a human monoclonal antibody that targets beta amyloid used in the treatment of Alzheimer's disease.
• Gatipotuzumab, is a humanized monoclonal antibody that targets MUC1 used in the treatment of cancer.
• Gavilimomab, is a mouse monoclonal antibody that targets CD147 (basigin) used in the treatment of graft versus host disease.
• Gedivumab, is a human monoclonal antibody that targets hemagglutinin HA.
• Gevokizumab is a humanized monoclonal antibody that targets IL-1β used in the treatment of diabetes etc..
• Gilvetmab, is a veterinary monoclonal antibody that targets PCDC1.
• Gimsilumab, is a human monoclonal antibody that targets CSF2 used in the treatment of rheumatoid arthritis.
• Glembatumumab vedotin, is a human monoclonal antibody that targets GPNMB used in the treatment of melanoma, breast cancer.
• Gomiliximab is a chimeric monoclonal antibody that targets CD23 (IgE receptor) used in the treatment of allergic asthma.
• Gosuranemab is a humanized monoclonal antibody that targets tau protein used in the treatment of progressive supranuclear palsy.
• Ianalumab, is a human monoclonal antibody that targets BAFF-R used in the treatment of autoimmune hepatitis.
• IBI308 is a humanmonoclonal antibody that targets PD-1 used in the treatment of squamous cell non-small cell lung cancer.
• Icrucumab is a human monoclonal antibody that targets VEGFR-1 used in the treatment of cancer etc..
• Ifabotuzumab, is a humanized monoclonal antibody that targets EPHA3 used in the treatment of glioblastoma multiforme.
• Iladatuzumab vedotin, is a humanized monoclonal antibody that targets CD79B used in the treatment of cancer.
• IMAB362 is a human monoclonal antibody that targets CLDN18.2 used in the treatment of gastrointestinal adenocarcinomas and pancreatic tumor.
• Imalumab, is a human monoclonal antibody that targets macrophage migration inhibitory factor (MIF) used in the treatment of cancer.
• Imaprelimab, is a humanized monoclonal antibody that targets melanoma cell adhesion molecule (MCAM).
• Imdevimab is a human monoclonal antibody that targets spike protein receptor binding domain (RBD) of SARS-CoV-2 used in the treatment of COVID-19.
• Imgatuzumab, is a humanized monoclonal antibody that targets Epidermal growth factor receptor (EGFR) used in the treatment of cancer.
• Inclacumab, is a human monoclonal antibody that targets selectin P used in the treatment of cardiovascular disease.
• Indatuximab ravtansine, is a chimeric monoclonal antibody that targets SDC1 used in the treatment of cancer.
• Indusatumab vedotin, is a human monoclonal antibody that targets GUCY2C used in the treatment of cancer.
• Intetumumab5, is a human monoclonal antibody that targets CD51 used in the treatment of solid tumors (prostate cancer, melanoma).
• Inolimomab is a mouse monoclonal antibody that targets CD25 (α chain of IL-2 receptor) used in the treatment of graft versus host disease.
• Iomab-B is a mousemonoclonal antibody that targets CD45 used in the treatment of ablation of bone marrow.
• Iratumumab, is a human monoclonal antibody that targets CD30 (TNFRSF8) used in the treatment of Hodgkin's lymphoma.
• Iscalimab, is a human monoclonal antibody that targets CD40.
• Istiratumab, is a human monoclonal antibody that targets IGF1R, CD221 used in the treatment of advanced solid tumors.
• Keliximab is a chimeric monoclonal antibody that targets CD4 used in the treatment of chronic asthma.
• Lacnotuzumab, is a humanized monoclonal antibody that targets CSF1, macrophage colony stimulating factor (MCSF) used in the treatment of cancer.
• Ladiratuzumab vedotin, is a humanized monoclonal antibody that targets LIV-1 used in the treatment of cancer.
• Lampalizumab, is a humanized (Fab), is a Complement factor D (CFD) used in the treatment of geographic atrophy secondary to age-related macular degeneration.
• Landogrozumab, is a humanized monoclonal antibody that targets GDF-8 used in the treatment of muscle wasting disorders.
• Laprituximab emtansine, is a chimeric monoclonal antibody that targets epidermal growth factor receptor (EGFR).
• Larcaviximab, is a chimeric monoclonal antibody that targets ebolavirus glycoprotein used in the treatment of Ebola virus.
• Lebrikizumab is a humanized monoclonal antibody that targets IL-13 used in the treatment of asthma.
• Lemalesomab, is a mouse monoclonal antibody that targets NCA-90 (granulocyte antigen) used in the treatment of diagnostic agent.
• Lendalizumab, is a humanized monoclonal antibody that targets C5.
• Lenvervimab, is a humanized monoclonal antibody that targets hepatitis B surfage antigen used in the treatment of hepatitis B.
• Lenzilumab, is a human monoclonal antibody that targets CSF2 used in the treatment of chronic myelomonocytic leukemia and juvenile myelomonocytic leukemia.
• Lerdelimumab, is a human monoclonal antibody that targets TGF beta 2 used in the treatment of reduction of scarring after glaucoma surgery.
• Leronlimab, is a humanized monoclonal antibody that targets CCR5 used in the treatment of breast cancer, HIV.
• Lesofavumab, is a human monoclonal antibody that targets hemagglutinin HA.
• Letolizumab, is a humanized (scFv), is a tumor necrosis factor related activation protein (TRAP) used in the treatment of inflammatory diseases.
• Lexatumumab, is a human monoclonal antibody that targets TRAIL-R2 used in the treatment of cancer.
• Libivirumab, is a human monoclonal antibody that targets hepatitis B surface antigen used in the treatment of hepatitis B.
• Lifastuzumab vedotin is a humanized monoclonal antibody that targets phosphate-sodium co-transporter used in the treatment of cancer.
• Ligelizumab, is a humanized monoclonal antibody that targets IGHE used in the treatment of severe asthma and chronic spontaneous urticaria.
• Loncastuximab tesirine, is a chimeric monoclonal antibody that targets CD19 used in the treatment of cancer.
• Losatuxizumab vedotin, is a chimeric/humanized monoclonal antibody that targets epidermal growth receptor factor (EGRF), ERBB1 HER1 used in the treatment of cancer.
• Lilotomab satetraxetan, is a mouse monoclonal antibody that targets CD37 used in the treatment of cancer.
• Lintuzumab is a humanized monoclonal antibody that targets CD33 used in the treatment of cancer.
• Lirilumab, is a human monoclonal antibody that targets KIR2D used in the treatment of solid and hematological cancers.
• Lodelcizumab, is a humanized monoclonal antibody that targets PCSK9 used in the treatment of hypercholesterolemia.
• Lorvotuzumab mertansine is a humanized monoclonal antibody that targets CD56 used in the treatment of cancer.
• Lucatumumab, is a human monoclonal antibody that targets CD40 used in the treatment of multiple myeloma, non-Hodgkin's lymphoma, Hodgkin's lymphoma.
• Lulizumab pegol, is a humanized monoclonal antibody that targets CD28 used in the treatment of autoimmune diseases.
• Lumiliximab, is a chimeric monoclonal antibody that targets CD23 (IgE receptor) used in the treatment of chronic lymphocytic leukemia.
• Lumretuzumab, is a humanized monoclonal antibody that targets ERBB3 (HER3) used in the treatment of cancer.
• Lupartumab, is a human (mab), is a ?.
• Lupartumab amadotin, is a human monoclonal antibody that targets LYPD3.
• Lutikizumab, is a humanized monoclonal antibody that targets interleukin 1 alpha.
• Maftivimab is a human (mab), is a part of Atoltivimab/maftivimab/odesivimab for treatment of Zaire ebolavirus (Ebola virus).
• Mapatumumab, is a human monoclonal antibody that targets TRAIL-R1 used in the treatment of cancer.
• Marstacimab is a human monoclonal antibody that targets tissue factor pathway inhibitor (TFPI) used in the treatment of bleeding with hemophilia.
• Maslimomab is a mousemonoclonal antibody that targets T-cell receptor.
• Mavrilimumab, is a human monoclonal antibody that targets GMCSF receptor α-chain used in the treatment of rheumatoid arthritis.
• Matuzumab, is a humanized monoclonal antibody that targets Epidermal growth factor receptor (EGFR) used in the treatment of colorectal, lung and stomach cancer.
• Metelimumab, is a human monoclonal antibody that targets TGF beta 1 used in the treatment of systemic scleroderma.
• Milatuzumab, is a humanized monoclonal antibody that targets CD74 used in the treatment of multiple myeloma and other hematological malignancies.
• Minretumomab is a mouse monoclonal antibody that targets TAG-72 used in the treatment of tumor detection (and therapy?).
• Mirikizumab, is a humanized monoclonal antibody that targets IL23A used in the treatment of psoriasis.
• Mirvetuximab soravtansine is a chimeric monoclonal antibody that targets folate receptor alpha used in the treatment of ovarian cancer.
• Mitumomab is a mouse monoclonal antibody that targets GD3 ganglioside used in the treatment of small cell lung carcinoma.
• Modotuximab is a chimeric monoclonal antibody that targets EGFR extracellular domain III used in the treatment of cancer.
• Monalizumab, is a humanized monoclonal antibody that targets NKG2A used in the treatment of rheumatoid arthritis, gynecologic malignancies, and other cancers.
• Morolimumab, is a human monoclonal antibody that targets Rhesus factor.
• Mosunetuzumab, is a humanized monoclonal antibody that targets CD3E, MS4A1, CD20 used in the treatment of cancer.
• Nacolomab tafenatox is a mouse (Fab), is a C242 antigen used in the treatment of colorectal cancer.
• Namilumab, is a human monoclonal antibody that targets CSF2.
• Naptumomab estafenatox, is a mouse (Fab), is a 5T4 used in the treatment of non-small cell lung carcinoma, renal cell carcinoma.
• Naratuximab emtansine, is a chimeric monoclonal antibody that targets CD37.
• Narnatumab is a human monoclonal antibody that targets MST1R (aka RON) used in the treatment of cancer.
• Navicixizumab, is a chimeric/humanized monoclonal antibody that targets DLL4 and VEGFA used in the treatment of cancer.
• Navivumab, is a human monoclonal antibody that targets influenza A virus hemagglutinin HA.
• Nebacumab is a human monoclonal antibody that targets endotoxin used in the treatment of sepsis.
• Nemolizumab, is a humanized monoclonal antibody that targets IL31RA used in the treatment of eczema.
• NEOD001 is a humanizedmonoclonal antibody that targets amyloid used in the treatment of primary systemic amyloidosis.
• Nerelimomab is a mouse monoclonal antibody that targets TNF-α.
• Nesvacumab is a human monoclonal antibody that targets angiopoietin 2 used in the treatment of cancer.
• Nirsevimab is a human monoclonal antibody that targets RSV fusion glycoprotein used in the treatment of respiratory syncytial virus.
• Ocaratuzumab is a humanized monoclonal antibody that targets CD20 used in the treatment of cancer.
• Odesivimab is a human (mab), is a part of Atoltivimab/maftivimab/odesivimab for treatment of Zaire ebolavirus (Ebola virus).
• Odulimomab is a mouse monoclonal antibody that targets LFA-1 (CD11a) used in the treatment of prevention of organ transplant rejections, immunological diseases.
• Oleclumab, is a human monoclonal antibody that targets 5'-nucleotidase used in the treatment of pancreatic and colorectal cancer.
• Olendalizumab, is a humanized monoclonal antibody that targets complement C5a used in the treatment of systemic lupus erythematosus, lupus nephritis, acute graft-versus-hose disease.
• Olokizumab, is a humanized monoclonal antibody that targets IL6 used in the treatment of rheumatoid arthritis.
• Omburtamab, is a mouse monoclonal antibody that targets CD276 used in the treatment of cancer.
• OMS721 is a humanmonoclonal antibody that targets MASP-2 used in the treatment of atypical hemolytic uremic syndrome.
• Onartuzumab is a humanized (Fab), is a human scatter factor receptor kinase used in the treatment of cancer.
• Ontuxizumab is a chimeric/humanized monoclonal antibody that targets TEM1 used in the treatment of cancer.
• Onvatilimab, is a human monoclonal antibody that targets VISTA (protein) (VSIR).
• Opicinumab is a human monoclonal antibody that targets LINGO-1 used in the treatment of multiple sclerosis.
• Orticumab, is a human monoclonal antibody that targets oxLDL.
• Otelixizumab, is a chimeric/humanized monoclonal antibody that targets CD3 used in the treatment of diabetes mellitus type 1.
• Otilimab is a human monoclonal antibody that targets GMCSF used in the treatment of osteoarthritis, rheumatoid arthritis.
• Otlertuzumab is a humanized monoclonal antibody that targets CD37 used in the treatment of cancer.
• Oxelumab, is a human monoclonal antibody that targets OX-40 used in the treatment of asthma.
• Ozanezumab is a humanized monoclonal antibody that targets NOGO-A used in the treatment of ALS and multiple sclerosis.
• Ozoralizumab, is a humanized monoclonal antibody that targets TNF-α used in the treatment of inflammation.
• Pagibaximab, is a chimeric monoclonal antibody that targets lipoteichoic acid used in the treatment of sepsis (Staphylococcus).
• Pamrevlumab, is a human monoclonal antibody that targets connective tissue growth factor (CTGF) used in the treatment of idiopathic pulmonary fibrosis (IPF), pancreatic cancer.
• Pankomab is a humanized monoclonal antibody that targets tumor specific glycosylation of MUC1 used in the treatment of ovarian cancer.
• Panobacumab, is a human monoclonal antibody that targets Pseudomonas aeruginosa used in the treatment of Pseudomonas aeruginosa infection.
• Parsatuzumab, is a humanized monoclonal antibody that targets EGFL7 used in the treatment of cancer.
• Pascolizumab, is a humanized monoclonal antibody that targets IL-4 used in the treatment of asthma.
• Pasotuxizumab, is a chimeric/humanized monoclonal antibody that targets folate hydrolase used in the treatment of cancer.
• Pateclizumab, is a humanized monoclonal antibody that targets lymphotoxin alpha (LTA) used in the treatment of TNF.
• Patritumab, is a human monoclonal antibody that targets ERBB3 (HER3) used in the treatment of cancer.
• PDR001 is a humanizedmonoclonal antibody that targets PD-1 used in the treatment of melanoma.
• Perakizumab, is a humanized monoclonal antibody that targets IL 17A used in the treatment of arthritis.
• Pexelizumab, is a humanized (scFv), is a C5 used in the treatment of reduction of side effects of cardiac surgery.
• Pidilizumab, is a humanized monoclonal antibody that targets PD-1 used in the treatment of cancer and infectious diseases.
• Pinatuzumab vedotin, is a humanized monoclonal antibody that targets CD22 used in the treatment of cancer.
• Pintumomab is a mouse monoclonal antibody that targets adenocarcinoma antigen used in the treatment of adenocarcinoma (imaging).
• Placulumab, is a human monoclonal antibody that targets human TNF used in the treatment of pain and inflammatory diseases.
• Prezalumab, is a human monoclonal antibody that targets human TNF.
• Plozalizumab, is a humanized monoclonal antibody that targets CCR2 used in the treatment of diabetic nephropathy and arteriovenous graft patency.
• Pogalizumab, is a humanized monoclonal antibody that targets tumor necrosis factor receptor (TNFR) superfamily member 4.
• Ponezumab is a humanized monoclonal antibody that targets human beta-amyloid used in the treatment of Alzheimer's disease.
• Porgaviximab, is a chimeric monoclonal antibody that targets Zaire ebolavirus glycoprotein used in the treatment of Ebola virus disease.
• Prasinezumab, is a humanized monoclonal antibody that targets sodium cyclopentadienide (NACP) used in the treatment of Parkinson's disease.
• Prezalizumab, is a humanized monoclonal antibody that targets inducible T-cell co-stimulatory ligand (ICOSL).
• Priliximab is a chimeric monoclonal antibody that targets CD4 used in the treatment of Crohn's disease, multiple sclerosis.
• Pritoxaximab, is a chimeric monoclonal antibody that targets E. coli shiga toxin type-1.
• Pritumumab is a human monoclonal antibody that targets vimentin used in the treatment of brain cancer.
• PRO 140 is a humanizedmonoclonal antibody that targets CCR5 used in the treatment of HIV infection.
• Quilizumab, is a humanized monoclonal antibody that targets IGHE used in the treatment of asthma.
• Radretumab, is a human monoclonal antibody that targets fibronectin extra domain-B used in the treatment of cancer.
• Rafivirumab, is a human monoclonal antibody that targets rabies virus glycoprotein used in the treatment of rabies (prophylaxis).
• Ralpancizumab is a humanized monoclonal antibody that targets PCSK9 used in the treatment of dyslipidemia.
• Ranevetmab is a veterinary monoclonal antibody that targets NGF used in the treatment of osteoarthritis in dogs.
• Raxibacumab, is a human monoclonal antibody that targets anthrax toxin, protective antigen used in the treatment of anthrax (prophylaxis and treatment).
• Ravagalimab, is a humanized monoclonal antibody that targets CD40 used in the treatment of Crohn's disease.
• Refanezumab is a humanized monoclonal antibody that targets myelin-associated glycoprotein used in the treatment of recovery of motor function after stroke.
• Regavirumab is a human monoclonal antibody that targets cytomegalovirus glycoprotein B used in the treatment of cytomegalovirus infection.
• REGN-EB3 is a human (mab), is a 3 mabs for ebola infection with FDA orphan drug status.
• Relatlimab is a human monoclonal antibody that targets LAG3 used in the treatment of melanoma.
• Remtolumab, is a human monoclonal antibody that targets interleukin 17 alpha, TNF.
• Rilotumumab is a human monoclonal antibody that targets hepatocyte growth factor (HGF) used in the treatment of solid tumors.
• Rinucumab is a human monoclonal antibody that targets platelet-derived growth factor receptor beta used in the treatment of neovascular age-related macular degeneration.
• Rivabazumab pegol, is a humanized monoclonal antibody that targets Pseudomonas aeruginosa type III secretion system.
• Robatumumab is a human monoclonal antibody that targets IGF-1 receptor (CD221) used in the treatment of cancer.
• Roledumab, is a human monoclonal antibody that targets RHD (gene) (RHD) used in the treatment of Rh disease.
• Romilkimab, is a chimeric/humanized monoclonal antibody that targets interleukin 13.
• Rontalizumab, is a humanized monoclonal antibody that targets IFN-α used in the treatment of systemic lupus erythematosus.
• Rosmantuzumab, is a humanized monoclonal antibody that targets root plate-specific spondin 3 used in the treatment of cancer.
• Rovalpituzumab tesirine, is a humanized monoclonal antibody that targets DLL3 used in the treatment of small cell lung cancer.
• Rozanolixizumab, is a chimeric/humanized monoclonal antibody that targets FCGRT used in the treatment of Immune thrombocytopenic purpura (ITP), myasthenia gravis.
• SA237 is a humanizedmonoclonal antibody that targets IL-6R used in the treatment of neuromyelitis optica and neuromyelitis optica spectrum disorders.
• Samalizumab, is a humanized monoclonal antibody that targets CD200 used in the treatment of cancer.
• Samrotamab vedotin, is a chimeric/humanized monoclonal antibody that targets LRRC15 used in the treatment of cancer.
• Satumomab pendetide is a mouse monoclonal antibody that targets TAG-72 used in the treatment of cancer (diagnosis).
• Selicrelumab, is a human monoclonal antibody that targets CD40.
• Seribantumab, is a human monoclonal antibody that targets ERBB3 (HER3) used in the treatment of cancer.
• Setoxaximab, is a chimeric monoclonal antibody that targets E. coli shiga toxin type-2.
• Setrusumab, is a human monoclonal antibody that targets sclerostin (SOST).
• Sevirumab is a humanmonoclonal antibody that targets cytomegalovirus used in the treatment of cytomegalovirus infection.
• Sibrotuzumab is a humanized monoclonal antibody that targets FAP (gene) (FAP) used in the treatment of cancer.
• SGN-CD19A is a humanized monoclonal antibody that targets CD19 used in the treatment of acute lymphoblastic leukemia and B-cell non-Hodgkin lymphoma.
• SHP647 is a humanmonoclonal antibody that targets mucosal addressin cell adhesion molecule used in the treatment of Crohn's disease.
• Sifalimumab, is a human monoclonal antibody that targets IFN-α used in the treatment of systemic lupus erythematosus (SLE), dermatomyositis, polymyositis.
• Simtuzumab, is a humanized monoclonal antibody that targets LOXL2 used in the treatment of fibrosis.
• Siplizumab, is a humanized monoclonal antibody that targets CD2 used in the treatment of psoriasis, graft-versus-host disease (prevention).
• Sirtratumab vedotin, is a human monoclonal antibody that targets SLITRK6 used in the treatment of cancer.
• Sirukumab is a human monoclonal antibody that targets IL-6 used in the treatment of rheumatoid arthritis.
• Sofituzumab vedotin is a humanized monoclonal antibody that targets CA-125 used in the treatment of ovarian cancer.
• Solanezumab, is a humanized monoclonal antibody that targets beta amyloid used in the treatment of Alzheimer's disease.
• Solitomab, is a mouse (BiTE), is a EpCAM used in the treatment of gastrointestinal, lung, and other cancers.
• Sonepcizumab, is a humanizedmonoclonal antibody that targets sphingosine-1-phosphate used in the treatment of choroidal and retinal neovascularization.
• Sontuzumab, is a humanized monoclonal antibody that targets episialin.
• Spartalizumab, is a humanized monoclonal antibody that targets PDCD1, CD279 used in the treatment of melanoma.
• Stamulumab, is a human monoclonal antibody that targets myostatin used in the treatment of muscular dystrophy.
• Suptavumab, is a human monoclonal antibody that targets RSVFR used in the treatment of medically attended lower respiratory disease.
• Sutimlimab, is a chimeric/humanized monoclonal antibody that targets C1s used in the treatment of cold agglutinin disease.
• Suvizumab, is a humanized monoclonal antibody that targets HIV-1 used in the treatment of viral infections.
• Suvratoxumab, is a human monoclonal antibody that targets Staphylococcus aureus alpha toxin used in the treatment of nosocomial pneumonia.
• Tabalumab, is a human monoclonal antibody that targets B-cell activating factor (BAFF) used in the treatment of B-cell cancers.
• Tadocizumab, is a humanized (Fab), is a integrin αIIbβ3 used in the treatment of percutaneous coronary intervention.
• Talacotuzumab, is a humanized monoclonal antibody that targets CD123 used in the treatment of leukemia etc..
• Talizumab, is a humanized monoclonal antibody that targets IgE used in the treatment of allergic reaction.
• Talquetamab is a human (bsmonoclonal antibody that targets GPRC5D, CD3 used in the treatment of relapsed or refractory multiple myeloma.
• Tanezumab, is a humanized monoclonal antibody that targets nerve growth factor (NGF) used in the treatment of pain.
• Taplitumomab paptox, is a mouse monoclonal antibody that targets CD19 used in the treatment of cancer(citation needed).
• Tarextumab is a human monoclonal antibody that targets Notch receptor used in the treatment of cancer.
• Tavolimab is a chimeric/humanized monoclonal antibody that targets CD134 used in the treatment of cancer.
• Teclistamab is a human (bsmonoclonal antibody that targets B-cell maturation antigen (BCMA), CD3 used in the treatment of relapsed or refractory multiple myeloma.
• Telimomab aritox is a mouse (Fab), is a ?.
• Telisotuzumab, is a humanized monoclonal antibody that targets HGFR used in the treatment of cancer.
• Telisotuzumab vedotin, is a humanized monoclonal antibody that targets HGFR used in the treatment of cancer.
• Tenatumomab, is a mouse monoclonal antibody that targets tenascin C used in the treatment of cancer.
• Teneliximab, is a chimeric monoclonal antibody that targets CD40 used in the treatment of autoimmune diseases and prevention of organ transplant rejection.
• Teplizumab, is a humanized monoclonal antibody that targets CD3 used in the treatment of diabetes mellitus type 1.
• Tepoditamab, is a human monoclonal antibody that targets dendritic cell-associated lectin 2 used in the treatment of cancer.
• Tesidolumab, is a human monoclonal antibody that targets C5.
• Tetulomab is a humanized monoclonal antibody that targets CD37 used in the treatment of cancer.
• Tezepelumab, is a human monoclonal antibody that targets thymic stromal lymphopoietin (TSLP) used in the treatment of asthma, atopic dermatitis.
• TGN1412 is a humanizedmonoclonal antibody that targets CD28 used in the treatment of chronic lymphocytic leukemia, rheumatoid arthritis.
• Tibulizumab, is a humanized monoclonal antibody that targets B-cell activating factor (BAFF) used in the treatment of autoimmune disorders.
• Tigatuzumab, is a humanized monoclonal antibody that targets TRAIL-R2 used in the treatment of cancer.
• Timigutuzumab, is a humanized monoclonal antibody that targets HER2 used in the treatment of cancer.
• Timolumab, is a human monoclonal antibody that targets AOC3.
• tiragolumab, is a human (mab), is a .
• Tiragotumab, is a human monoclonal antibody that targets TIGIT used in the treatment of cancer.
• Tislelizumab, is a humanized monoclonal antibody that targets PCDC1, CD279 used in the treatment of non-small cell lung cancer.
• Tisotumab vedotin, is a human monoclonal antibody that targets coagulation factor III used in the treatment of relapsed or refractory cervical cancer.
• TNX-650 is a humanizedmonoclonal antibody that targets IL-13 used in the treatment of Hodgkin's lymphoma.
• Tomuzotuximab, is a humanized monoclonal antibody that targets epidermal growth factor receptor (EGFR), HER1 used in the treatment of cancer.
• Toralizumab, is a humanized monoclonal antibody that targets CD154 (CD40L) used in the treatment of rheumatoid arthritis, lupus nephritis etc..
• Tosatoxumab, is a human monoclonal antibody that targets Staphylococcus aureus.
• Tovetumab is a human monoclonal antibody that targets PDGFRA used in the treatment of cancer.
• Tralokinumab is a human monoclonal antibody that targets IL-13 used in the treatment of asthma, atopic dermatitis.
• Tregalizumab, is a humanized monoclonal antibody that targets CD4.
• Tremelimumab, is a human monoclonal antibody that targets CTLA-4 used in the treatment of non-small cell lung, head & neck, urothelial cancer.
• Trevogrumab is a human monoclonal antibody that targets growth differentiation factor 8 used in the treatment of muscle atrophy due to orthopedic disuse and sarcopenia.
• Tucotuzumab celmoleukin, is a humanized monoclonal antibody that targets EpCAM used in the treatment of cancer.
• Tuvirumab is a humanmonoclonal antibody that targets hepatitis B virus used in the treatment of chronic hepatitis B.
• Ublituximab, is a chimeric monoclonal antibody that targets MS4A1 used in the treatment of multiple sclerosis, chronic lymphocytic leukemia.
• Ulocuplumab, is a human monoclonal antibody that targets CXCR4 (CD184) used in the treatment of hematologic malignancies.
• Urelumab, is a human monoclonal antibody that targets 4-1BB (CD137) used in the treatment of cancer etc..
• Urtoxazumab, is a humanized monoclonal antibody that targets Escherichia coli used in the treatment of diarrhoea caused by E. coli.
• Utomilumab, is a human monoclonal antibody that targets 4-1BB (CD137) used in the treatment of diffuse large B-cell lymphoma.
• Vadastuximab talirine, is a chimeric monoclonal antibody that targets CD33 used in the treatment of Acute myeloid leukemia.
• Vanalimab, is a humanized monoclonal antibody that targets CD40.
• Vandortuzumab vedotin, is a humanized monoclonal antibody that targets STEAP1 used in the treatment of cancer.
• Vantictumab is a human monoclonal antibody that targets Frizzled receptor used in the treatment of cancer.
• Vanucizumab, is a humanized monoclonal antibody that targets angiopoietin 2 used in the treatment of cancer.
• Vapaliximab, is a chimeric monoclonal antibody that targets AOC3 (VAP-1).
• Varisacumab, is a human monoclonal antibody that targets VEGF-A used in the treatment of angiogenesis.
• Varlilumab, is a human monoclonal antibody that targets CD27 used in the treatment of solid tumors and hematologic malignancies.
• Vatelizumab, is a humanized monoclonal antibody that targets ITGA2 (CD49b).
• Veltuzumab, is a humanized monoclonal antibody that targets CD20 used in the treatment of non-Hodgkin's lymphoma.
• Vepalimomab is a mouse monoclonal antibody that targets AOC3 (VAP-1) used in the treatment of inflammation.
• Vesencumab, is a human monoclonal antibody that targets NRP1 used in the treatment of solid malignancies.
• Vobarilizumab, is a humanized (scFv), is a IL6R used in the treatment of inflammatory autoimmune diseases.
• Volociximab, is a chimeric monoclonal antibody that targets integrin α5β1 used in the treatment of solid tumors.
• Vonlerolizumab, is a humanized monoclonal antibody that targets CD134 used in the treatment of cancer.
• Vopratelimab, is a humanized monoclonal antibody that targets CD278, aka ICOS.
• Vorsetuzumab mafodotin is a humanized monoclonal antibody that targets CD70 used in the treatment of cancer.
• Vunakizumab, is a humanized monoclonal antibody that targets interleukin 17 alpha.
• Xentuzumab, is a humanized monoclonal antibody that targets IGF1, IGF2.
• XMAB-5574 is a humanizedmonoclonal antibody that targets CD19 used in the treatment of diffuse large B-cell lymphoma.
• Zalutumumab, is a human monoclonal antibody that targets Epidermal growth factor receptor (EGFR) used in the treatment of squamous cell carcinoma of the head and neck.
• Zanolimumab, is a human monoclonal antibody that targets CD4 used in the treatment of rheumatoid arthritis, psoriasis, T-cell lymphoma.
• Zatuximab, is a chimeric monoclonal antibody that targets HER1 used in the treatment of cancer.
• Zenocutuzumab, is a humanized monoclonal antibody that targets ERBB3, HER3 used in the treatment of cancer.
• Ziralimumab is a human monoclonal antibody that targets CD147 (basigin).
• Zolbetuximab, tradename IMAB362, Claudiximab, is a chimeric monoclonal antibody that targets Claudin 18 Isoform 2 used in the treatment of gastric cancer, gastrointestinal adenocarcinoma and pancreatic cancer.
• Zolimomab aritox is a mouse monoclonal antibody that targets CD5 used in the treatment of systemic lupus erythematosus, graft-versus-host disease.

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