Monoclonal antibodies
Monoclonal antibodies is an antibody that is produced in the laboratory so that it will react with only one specific foreign protein; used to help diagnose certain kinds of cancer
List of monoclonal antibodies[edit | edit source]
- Bezlotoxumab trade name (Zinplava), is a human monoclonal antibody that targets Clostridium difficile used in the treatment of Clostridium difficile colitis.
- Cosfroviximab trade name (ZMapp), is a chimeric monoclonal antibody that targets ebolavirus glycoprotein used in the treatment of Ebola virus.
- Ibritumomab tiuxetan trade name (Zevalin), is a mouse monoclonal antibody that targets CD20 used in the treatment of non-Hodgkin's lymphoma.
- Daclizumab trade name (Zenapax), is a humanized monoclonal antibody that targets CD25 (α chain of IL-2 receptor) used in the treatment of prevention of organ transplant rejections, multiple sclerosis.
- Ipilimumab trade name (Yervoy), is a human monoclonal antibody that targets CD152 used in the treatment of melanoma.
- Omalizumab trade name (Xolair), is a humanized monoclonal antibody that targets IgE Fc region used in the treatment of allergic asthma.
- Bermekimab trade name (Xilonix), is a human monoclonal antibody that targets IL1A used in the treatment of colorectal cancer.
- Eptinezumab trade name (Vyepti), is a humanized monoclonal antibody that targets calcitonin gene-related peptide used in the treatment of migraine.
- Oportuzumab monatox trade name (Vicinium), is a humanized (scFv), is a EpCAM used in the treatment of bladder cancer.
- Nofetumomab merpentan, (Verluma), is a mouse (Fab), is a ? used in the treatment of cancer (diagnosis).
- Panitumumab trade name (Vectibix), is a human monoclonal antibody that targets epidermal growth factor receptor (EGFR) used in the treatment of colorectal cancer.
- Racotumomab trade name (Vaxira), is a mouse monoclonal antibody that targets NGNA ganglioside used in the treatment of non-small cell lung cancer.
- Inebilizumab trade name (Uplizna), is a humanized monoclonal antibody that targets CD19 used in the treatment of cancer, systemic sclerosis, multiple sclerosis.
- Dinutuximab trade name (Unituxin), is a chimeric monoclonal antibody that targets GD2 ganglioside used in the treatment of neuroblastoma.
- Ravulizumab trade name (Ultomiris), is a humanized monoclonal antibody that targets C5 used in the treatment of paroxysmal nocturnal hemoglobinuria, atypical hemolytic uremic syndrome.
- Natalizumab trade name (Tysabri), is a humanized monoclonal antibody that targets integrin α4 used in the treatment of multiple sclerosis, Crohn's disease.
- Ibalizumab trade name (Trogarzo), is a humanized monoclonal antibody that targets CD4 used in the treatment of HIV infection.
- Sacituzumab govitecan trade name (Trodelvy), is a humanized monoclonal antibody that targets TROP-2 used in the treatment of triple-negative breast cancer.
- Guselkumab trade name (Tremfya), is a human monoclonal antibody that targets IL23 used in the treatment of psoriasis.
- Pemtumomab trade name (Theragyn), is a mousemonoclonal antibody that targets MUC1 used in the treatment of cancer.
- Teprotumumab trade name (Tepezza), is a human monoclonal antibody that targets IGF-1 receptor (CD221) used in the treatment of thyroid eye disease.
- Atezolizumab trade name (Tecentriq), is a humanized monoclonal antibody that targets PD-L1 used in the treatment of cancer.
- Ixekizumab trade name (Taltz), is a humanized monoclonal antibody that targets IL 17A used in the treatment of autoimmune diseases.
- Lanadelumab trade name (Takhzyro), is a human monoclonal antibody that targets kallikrein used in the treatment of angioedema.
- Tamtuvetmab trade name (Tactress), is a veterinary monoclonal antibody that targets CD52.
- Palivizumab trade name (Synagis, Abbosynagis), is a humanized monoclonal antibody that targets F protein of respiratory syncytial virus used in the treatment of respiratory syncytial virus (prevention).
- Siltuximab trade name (Sylvant), is a chimeric monoclonal antibody that targets IL-6 used in the treatment of cancer.
- Ustekinumab trade name (Stelara), is a human monoclonal antibody that targets IL-12, IL-23 used in the treatment of multiple sclerosis, psoriasis, psoriatic arthritis.
- Eculizumab trade name (Soliris), is a humanized monoclonal antibody that targets C5 used in the treatment of paroxysmal nocturnal hemoglobinuria, atypical hemolytic uremic syndrome.
- Risankizumab trade name (Skyrizi), is a humanized monoclonal antibody that targets IL23A used in the treatment of Crohn's disease, psoriasis, psoriatic arthritis, and asthma.
- Basiliximab trade name (Simulect), is a chimeric monoclonal antibody that targets CD25 (α chain of IL-2 receptor) used in the treatment of prevention of organ transplant rejections.
- Golimumab trade name (Simponi), is a human monoclonal antibody that targets TNF-α used in the treatment of rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis.
- Brodalumab trade name (Siliq), is a human monoclonal antibody that targets IL-17 used in the treatment of Plaque psoriasis.
- Besilesomab trade name (Scintimun), is a mouse monoclonal antibody that targets Carcinoembryonic antigen (CEA)-related antigen used in the treatment of inflammatory lesions and metastases (detection).
- Isatuximab trade name (Sarclisa), is a chimeric monoclonal antibody that targets CD38 used in the treatment of multiple myeloma.
- Ertumaxomab trade name (Rexomun), is a rat/mouse hybrid (3funct), is a HER2/neu, CD3 used in the treatment of breast cancer etc..
- Evolocumab trade name (Repatha), is a human monoclonal antibody that targets PCSK9 used in the treatment of hypercholesterolemia.
- Abciximab trade name (ReoPro), is a chimeric (Fab), is a CD41 (integrin alpha-IIb) used in the treatment of platelet aggregation inhibitor.
- Girentuximab trade name (Rencarex), is a chimeric monoclonal antibody that targets carbonic anhydrase 9 (CA-IX) used in the treatment of clear cell renal cell carcinoma.
- Catumaxomab trade name (Removab), is a rat/mouse hybrid (3funct), is a EpCAM, CD3 used in the treatment of ovarian cancer, malignant ascites, gastric cancer.
- Infliximab trade name (Remicade), is a chimeric monoclonal antibody that targets TNF-α used in the treatment of rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, psoriasis, Crohn's disease, ulcerative colitis.
- Efalizumab trade name (Raptiva), is a humanized monoclonal antibody that targets LFA-1 (CD11a) used in the treatment of psoriasis (blocks T-cell migration).
- Rmab trade name (RabiShield), is a humanmonoclonal antibody that targets rabies virus G glycoprotein used in the treatment of post-exposure prophylaxis of rabies.
- Dinutuximab beta trade name (Qarziba), is a chimeric monoclonal antibody that targets GD2 ganglioside used in the treatment of neuroblastoma.
- Capromab trade name (Prostascint), is a mouse monoclonal antibody that targets Glutamate carboxypeptidase II used in the treatment of prostate cancer (detection).
- Denosumab trade name (Prolia), is a human monoclonal antibody that targets RANKL used in the treatment of osteoporosis, bone metastases etc..
- Idarucizumab trade name (Praxbind), is a humanized monoclonal antibody that targets dabigatran used in the treatment of reversal of anticoagulant effects of dabigatran.
- Alirocumab trade name (Praluent), is a human monoclonal antibody that targets PCSK9 used in the treatment of hypercholesterolemia.
- Mogamulizumab trade name (Poteligeo), is a humanized monoclonal antibody that targets CCR4 used in the treatment of adult T-cell leukemia/lymphoma.
- Necitumumab trade name (Portrazza), is a human monoclonal antibody that targets Epidermal growth factor receptor (EGFR) used in the treatment of non-small cell lung carcinoma.
- Polatuzumab vedotin trade name (Polivy), is a humanized monoclonal antibody that targets CD79B used in the treatment of diffuse large B-cell lymphoma.
- Pertuzumab trade name (Perjeta), is a humanized monoclonal antibody that targets HER2/neu used in the treatment of cancer.
- Edrecolomab trade name (Panorex), is a mouse monoclonal antibody that targets EpCAM used in the treatment of colorectal carcinoma.
- Enfortumab vedotin trade name (Padcev), is a human monoclonal antibody that targets nectin-4 used in the treatment of urothelial cancer.
- Oregovomab trade name (OvaRex), is a mouse monoclonal antibody that targets CA-125 used in the treatment of ovarian cancer.
- Muromonab-CD3 trade name (Orthoclone OKT3), is a mouse monoclonal antibody that targets CD3 used in the treatment of prevention of organ transplant rejections.
- Nivolumab trade name (Opdivo), is a human monoclonal antibody that targets PD-1 used in the treatment of cancer.
- Ocrelizumab trade name (Ocrevus), is a humanized monoclonal antibody that targets CD20 used in the treatment of multiple sclerosis.
- Visilizumab trade name (Nuvion), is a humanized monoclonal antibody that targets CD3 used in the treatment of Crohn's disease, ulcerative colitis.
- Motavizumab trade name (Numax), is a humanized monoclonal antibody that targets respiratory syncytial virus used in the treatment of respiratory syncytial virus (prevention).
- Fanolesomab trade name (NeutroSpec), is a mouse monoclonal antibody that targets CD15 used in the treatment of appendicitis (diagnosis).
- Imciromab trade name (Myoscint), is a mouse monoclonal antibody that targets cardiac myosin used in the treatment of cardiac imaging.
- Gemtuzumab ozogamicin trade name (Mylotarg), is a humanized monoclonal antibody that targets CD33 used in the treatment of acute myelogenous leukemia.
- Efungumab trade name (Mycograb), is a human (scFv), is a Hsp90 used in the treatment of invasive Candida infection.
- Tafasitamab trade name (Monjuvi), is a humanized (from mouse) monoclonal antibody that targets CD19 used in the treatment of relapsed or refractory diffuse large B-cell lymphoma.
- Margetuximab trade name (Margenza8)) is a humanized monoclonal antibody that targets HER2 used in the treatment of breast cancer.
- Rituximab trade name (MabThera, Rituxan), is a chimeric monoclonal antibody that targets CD20 used in the treatment of lymphomas, leukemias, some autoimmune disorders.
- Bectumomab trade name (LymphoScan), is a mouse (Fab'), is a CD22 used in the treatment of non-Hodgkin's lymphoma (detection).
- FBTA057 trade name (Lymphomun), is a rat/mouse hybrid (3funct), is a CD20 used in the treatment of chronic lymphocytic leukaemia.
- Moxetumomab pasudotox trade name (Lumoxiti), is a mouse monoclonal antibody that targets CD22 used in the treatment of hairy cell leukemia.
- Ranibizumab trade name (Lucentis), is a humanized (Fab), is a VEGF-A used in the treatment of macular degeneration (wet form).
- Cemiplimab trade name (Libtayo), is a human monoclonal antibody that targets PDCD1 used in the treatment of cutaneous squamous cell carcinoma.
- Sulesomab trade name (LeukoScan), is a mouse (Fab'), is a NCA-90 (granulocyte antigen) used in the treatment of osteomyelitis (imaging).
- Rovelizumab trade name (LeukArrest), is a humanized monoclonal antibody that targets CD11, CD18 used in the treatment of haemorrhagic shock etc..
- Alemtuzumab trade name (Lemtrada, Campath), is a humanized monoclonal antibody that targets CD52 used in the treatment of multiple sclerosis.
- Olaratumab trade name (Lartruvo), is a human monoclonal antibody that targets PDGF-R α used in the treatment of cancer.
- Pembrolizumab trade name (Keytruda), is a humanized monoclonal antibody that targets PD-1 used in the treatment of melanoma and other cancers.
- Sarilumab trade name (Kevzara), is a human monoclonal antibody that targets IL6 used in the treatment of rheumatoid arthritis, ankylosing spondylitis.
- Trastuzumab duocarmazine trade name (Kadcyla), is a humanized monoclonal antibody that targets HER2/neu used in the treatment of breast cancer.
- Trastuzumab emtansine trade name (Kadcyla), is a humanized monoclonal antibody that targets HER2/neu used in the treatment of breast cancer.
- Atoltivimab/maftivimab/odesivimab trade name (Inmazeb), is a human (mab), is a treatment of Zaire ebolavirus (Ebola virus).
- Igovomab trade name (Indimacis-125), is a mouse (F(ab')2), is a CA-125 used in the treatment of ovarian cancer (diagnosis).
- Durvalumab trade name (Imfinzi), is a human monoclonal antibody that targets PD-L1 used in the treatment of cancer.
- Tildrakizumab trade name (Ilumya), is a humanized monoclonal antibody that targets IL23 used in the treatment of immunologically mediated inflammatory disorders.
- Canakinumab trade name (Ilaris), is a human monoclonal antibody that targets IL-1 used in the treatment of cryopyrin-associated periodic syndrome.
- Altumomab pentetate trade name (Hybri-ceaker), is a mouse monoclonal antibody that targets Carcinoembryonic antigen (CEA) used in the treatment of colorectal cancer (diagnosis).
- Fontolizumab trade name (HuZAF), is a humanized monoclonal antibody that targets IFN-γ used in the treatment of Crohn's disease etc..
- Adalimumab trade name (Humira), is a human monoclonal antibody that targets TNF-α used in the treatment of rheumatoid arthritis, Crohn's disease, plaque psoriasis, psoriatic arthritis, ankylosing spondylitis, juvenile idiopathic arthritis, hemolytic disease of the newborn.
- Votumumab trade name (HumaSPECT), is a human monoclonal antibody that targets tumor antigen CTAA16.88 used in the treatment of colorectal tumors.
- Clivatuzumab tetraxetan trade name (hPAM4-Cide), is a humanized monoclonal antibody that targets MUC1 used in the treatment of pancreatic cancer.
- Trastuzumab trade name (Herceptin), is a humanized monoclonal antibody that targets HER2/neu used in the treatment of breast cancer.
- Emicizumab trade name (Hemlibra), is a humanized monoclonal antibody that targets activated F9, F10 used in the treatment of haemophilia A.
- Obinutuzumab trade name (Gazyva), is a humanized monoclonal antibody that targets CD20 used in the treatment of chronic lymphatic leukemia.
- Emapalumab trade name (Gamifant), is a human monoclonal antibody that targets interferon gamma used in the treatment of hemophagocytic lymphohistiocytosis.
- Biciromab trade name (FibriScint), is a mouse (Fab'), is a fibrin II, beta chain used in the treatment of thromboembolism (diagnosis).
- Benralizumab trade name (Fasenra), is a humanized monoclonal antibody that targets CD125 used in the treatment of asthma.
- Romosozumab trade name (Evenity), is a humanized monoclonal antibody that targets sclerostin used in the treatment of osteoporosis.
- Cetuximab trade name (Erbitux), is a chimeric monoclonal antibody that targets Epidermal growth factor receptor (EGFR) used in the treatment of metastatic colorectal cancer and head and neck cancer.
- Vedolizumab trade name (Entyvio), is a humanized monoclonal antibody that targets integrin α4β7 used in the treatment of Crohn's disease, ulcerative colitis.
- Satralizumab trade name (Enspryng), is a humanized monoclonal antibody that targets IL6 receptor used in the treatment of neuromyelitis optica.
- Elotuzumab trade name (Empliciti), is a humanized monoclonal antibody that targets SLAMF7 used in the treatment of multiple myeloma.
- Galcanezumab trade name (Emgality), is a humanized monoclonal antibody that targets calcitonin used in the treatment of migraine.
- TRBS07 trade name (Ektomonoclonal antibody that targets | 3funct), is a GD2 ganglioside used in the treatment of melanoma.
- Netakimab trade name (Efleira), is a chimeric monoclonal antibody that targets interleukin 17A used in the treatment of plaque psoriasis.
- Ansuvimab trade name (Ebanga), is a human monoclonal antibody that targets Ebola virus glycoprotein used in the treatment of treatment of Zaire ebolavirus (Ebola virus).
- Dupilumab trade name (Dupixent), is a human monoclonal antibody that targets IL-4Rα used in the treatment of atopic dermatitis, asthma, nasal polyps.
- Daratumumab trade name (Darzalex), is a human monoclonal antibody that targets CD38 used in the treatment of multiple myeloma.
- Naxitamab trade name (Danyelza), is a humanizedmonoclonal antibody that targets c-Met used in the treatment of high-risk neuroblastoma and refractory osteomedullary disease.
- Lokivetmab trade name (Cytopoint7)) is a veterinary monoclonal antibody that targets Canis lupus familiaris IL31 used in the treatment of clinical signs of atopic dermatitis in dogs.
- Ramucirumab]] (Cyramza), is a human monoclonal antibody that targets VEGFR2 used in the treatment of solid tumors.
- Burosumab trade name (Crysvita), is a human monoclonal antibody that targets FGF 23 used in the treatment of X-linked hypophosphatemia.
- Secukinumab trade name (Cosentyx), is a human monoclonal antibody that targets IL 17A used in the treatment of uveitis, rheumatoid arthritis psoriasis.
- Reslizumab trade name (Cinqair), is a humanized monoclonal antibody that targets IL-5 used in the treatment of inflammations of the airways, skin and gastrointestinal tract.
- Certolizumab pegol trade name (Cimzia), is a humanized (Fab'), is a TNF-α used in the treatment of Crohn's disease, rheumatoid arthritis, axial spondyloarthritis, psoriasis arthritis.
- Arcitumomab trade name (CEA-Scan), is a mouse (Fab'), is a Carcinoembryonic antigen (CEA) used in the treatment of gastrointestinal cancers (diagnosis).
- Labetuzumab trade name (CEA-Cide), is a humanized monoclonal antibody that targets Carcinoembryonic antigen (CEA) used in the treatment of colorectal cancer.
- Caplacizumab trade name (Cablivi), is a humanized (sdAb), is a VWF used in the treatment of thrombotic thrombocytopenic purpura, thrombosis.
- Mepolizumab trade name (Bosatria), is a humanized monoclonal antibody that targets IL-5 used in the treatment of asthma and white blood cell diseases.
- Blontuvetmab trade name (Blontress), is a veterinary monoclonal antibody that targets CD20.
- Blinatumomab trade name (Blincyto), is a mouse (BiTE), is a CD19 used in the treatment of pre-B Acute lymphoblastic leukemia (ALL) (CD19+).
- Belantamab mafodotin trade name (Blenrep), is a humanized monoclonal antibody that targets B-cell maturation antigen (BCMA) used in the treatment of relapsed or refractory multiple myeloma.
- Nimotuzumab trade name (BioMab-EGFR, Theracim, Theraloc), is a humanized monoclonal antibody that targets epidermal growth factor receptor (EGFR) used in the treatment of squamous cell carcinoma, head and neck cancer, nasopharyngeal cancer, glioma.
- Tositumomab trade name (Bexxar), is a mousemonoclonal antibody that targets CD20 used in the treatment of follicular lymphoma.
- Inotuzumab ozogamicin trade name (Besponsa), is a humanized monoclonal antibody that targets CD22 used in the treatment of Acute lymphoblastic leukemia (ALL).
- Brolucizumab trade name (Beovu), is a humanized (scFv), is a vascular endothelial growth factor A (VEGFA) used in the treatment of wet age-related macular degeneration.
- Belimumab trade name (Benlysta), is a human monoclonal antibody that targets B-cell activating factor (BAFF) used in the treatment of systemic lupus erythematosus without renal or CNS involvement.
- Avelumab trade name (Bavencio), is a human monoclonal antibody that targets PD-L1 used in the treatment of cancer.
- Bevacizumab trade name (Avastin), is a humanized monoclonal antibody that targets VEGF-A used in the treatment of metastatic cancer, retinopathy of prematurity.
- Tefibazumab trade name (Aurexis), is a humanized monoclonal antibody that targets clumping factor A used in the treatment of Staphylococcus aureus infection.
- Ofatumumab trade name (Arzerra, Kesimpta4)) is a human monoclonal antibody that targets CD20 used in the treatment of chronic lymphocytic leukemia.
- multiple sclerosis.
- Ruplizumab trade name (Antova), is a humanized monoclonal antibody that targets CD154 (CD40L) used in the treatment of rheumatic diseases.
- Obiltoxaximab trade name (Anthim), is a chimeric monoclonal antibody that targets Bacillus anthracis anthrax used in the treatment of Bacillus anthracis spores.
- Itolizumab trade name (Alzumonoclonal antibody that targets humanized monoclonal antibody that targets CD6 used in the treatment of psoriasis.
- Fremanezumab trade name (Ajovy), is a humanized monoclonal antibody that targets calcitonin gene-related peptide alpha used in the treatment of migraine and cluster headache.
- Erenumab trade name (Aimovig), is a human monoclonal antibody that targets calcitonin gene-related peptide receptor (CGRP) used in the treatment of migraine.
- Tacatuzumab tetraxetan trade name (AFP-Cide), is a humanized monoclonal antibody that targets alpha-fetoprotein used in the treatment of cancer.
- Brentuximab vedotin trade name (Adcentris), is a chimeric monoclonal antibody that targets CD30 (TNFRSF8) used in the treatment of Hodgkin's lymphoma.
- anaplastic large-cell lymphoma.
- Crizanlizumab trade name (Adakveo), is a humanized monoclonal antibody that targets selectin P used in the treatment of sickle-cell disease.
- Tocilizumab trade name (Actemra, RoActemra), is a humanized monoclonal antibody that targets IL-6 receptor used in the treatment of rheumatoid arthritis.
- Etaracizumab trade name (Abegrin), is a humanized monoclonal antibody that targets integrin αvβ3 used in the treatment of melanoma, prostate cancer, ovarian cancer etc..
- 3F8 is a mouse monoclonal antibody that targets GD2 ganglioside used in the treatment of neuroblastoma.
- 8H, is a mouse monoclonal antibody that targets B7-H3 used in the treatment of neuroblastoma, sarcoma, metastatic brain cancers.
- Abagovomab, is a mouse monoclonal antibody that targets CA-125 (imitation) used in the treatment of ovarian cancer.
- Abituzumab, is a humanized monoclonal antibody that targets CD51 used in the treatment of cancer.
- Abrezekimab, is a humanized (Fab), is a interleukin 13.
- Abrilumab, is a human monoclonal antibody that targets integrin α4β7 used in the treatment of inflammatory bowel disease, ulcerative colitis, Crohn's disease.
- Actoxumab, is a human monoclonal antibody that targets Clostridium difficile used in the treatment of Clostridium difficile colitis.
- Adecatumumab, is a human monoclonal antibody that targets EpCAM used in the treatment of prostate and breast cancer.
- Aducanumab, is a human monoclonal antibody that targets beta-amyloid used in the treatment of Alzheimer's disease.
- Afasevikumab, is a human monoclonal antibody that targets IL17A and IL17F used in the treatment of multiple sclerosis.
- Afelimomab, is a mouse (F(ab')2), is a TNF-α used in the treatment of sepsis.
- Alacizumab pegol, is a humanized (F(ab')2), is a VEGFR2 used in the treatment of cancer.
- Amatuximab, is a chimeric monoclonal antibody that targets mesothelin used in the treatment of cancer.
- Amivantamab is a human (bsmonoclonal antibody that targets Epidermal growth factor receptor (EGFR), cMet used in the treatment of non-small cell lung cancer.
- Anatumomab mafenatox, is a mouse (Fab), is a Tumor-associated glycoprotein 72 (TAG-72) used in the treatment of non-small cell lung cancer.
- Andecaliximab, is a chimeric monoclonal antibody that targets gelatinase B used in the treatment of gastric cancer or gastroesophageal junction adenocarcinoma.
- Anetumab ravtansine, is a human monoclonal antibody that targets mesothelin (MSLN) used in the treatment of cancer.
- Anifrolumab, is a human monoclonal antibody that targets interferon α/β receptor used in the treatment of systemic lupus erythematosus.
- Anrukinzumab1 trade name IMA-63, is a humanized monoclonal antibody that targets IL-13 used in the treatment of asthma.
- Apolizumab, is a humanized monoclonal antibody that targets HLA-DR ? used in the treatment of hematological cancers.
- Aprutumab ixadotin, is a human monoclonal antibody that targets FGFR2.
- Ascrinvacumab, is a human monoclonal antibody that targets activin receptor-like kinase 1 used in the treatment of cancer.
- Aselizumab, is a humanized monoclonal antibody that targets L-selectin (CD62L) used in the treatment of severely injured patients.
- Atidortoxumab, is a human monoclonal antibody that targets Staphylococcus aureus alpha toxin.
- Atinumab, is a human monoclonal antibody that targets RTN4.
- Atoltivimab is a human (mab), is a part of Atoltivimab/maftivimab/odesivimab for treatment of Zaire ebolavirus (Ebola virus).
- Atorolimumab, is a human monoclonal antibody that targets Rhesus factor used in the treatment of hemolytic disease of the newborn(citation needed).
- Azintuxizumab vedotin, is a chimeric/humanized monoclonal antibody that targets CD319 used in the treatment of cancer.
- Bapineuzumab, is a humanized monoclonal antibody that targets beta amyloid used in the treatment of Alzheimer's disease.
- Bavituximab, is a chimeric monoclonal antibody that targets phosphatidylserine used in the treatment of cancer, viral infections.
- BCD-100 is a humanmonoclonal antibody that targets PD-1 used in the treatment of melanoma.
- Begelomab, is a mouse monoclonal antibody that targets DPP4.
- Bemarituzumab, is a humanized monoclonal antibody that targets FGFR2 used in the treatment of gastric cancer or gastroesophageal junction adenocarcinoma.
- Berlimatoxumab, is a human monoclonal antibody that targets Staphylococcus aureus bi-component leukocidin.
- Bersanlimab, is a human monoclonal antibody that targets ICAM-1.
- Bertilimumab, is a human monoclonal antibody that targets CCL11 (eotaxin-1) used in the treatment of severe allergic disorders.
- Bimagrumab, is a human monoclonal antibody that targets ACVR2B used in the treatment of myostatin inhibitor.
- Bimekizumab, is a humanized monoclonal antibody that targets IL 17A and IL 17F used in the treatment of ankylosing spondylitis, psoriasis.
- Birtamimab is a chimeric monoclonal antibody that targets serum amyloid A protein used in the treatment of amyloidosis.
- Bivatuzumab, is a humanized monoclonal antibody that targets CD44 v6 used in the treatment of squamous cell carcinoma.
- Bleselumab, is a human monoclonal antibody that targets CD40 used in the treatment of organ transplant rejection.
- Blosozumab, is a humanized monoclonal antibody that targets SOST used in the treatment of osteoporosis.
- Bococizumab, is a humanized monoclonal antibody that targets PCSK9 used in the treatment of dyslipidemia.
- Brazikumab, is a human monoclonal antibody that targets IL23 used in the treatment of Crohn's disease.
- Briakinumab, is a human monoclonal antibody that targets IL-12, IL-23 used in the treatment of psoriasis, rheumatoid arthritis, inflammatory bowel diseases, multiple sclerosis.
- Brontictuzumab, is a humanized monoclonal antibody that targets Notch 1 used in the treatment of cancer.
- Cabiralizumab, is a humanized monoclonal antibody that targets CSF1R used in the treatment of metastatic pancreatic cancer.
- Camidanlumab tesirine, is a human monoclonal antibody that targets CD25 (α chain of IL-2 receptor) used in the treatment of B-cell Hodgkin's lymphoma, non-Hodgkin lymphoma, acute lymphoblastic leukemia, acute myeloid leukemia.
- Camrelizumab, is a humanized monoclonal antibody that targets PD-1 used in the treatment of hepatocellular carcinoma.
- Cantuzumab mertansine, is a humanized monoclonal antibody that targets CanAg (a glycoform of MUC1) used in the treatment of colorectal cancer etc..
- Cantuzumab ravtansine, is a humanized monoclonal antibody that targets CanAg (a glycoform of MUC1) used in the treatment of cancers.
- Casirivimab is a human monoclonal antibody that targets spike protein receptor binding domain (RBD) of SARS-CoV-2 used in the treatment of COVID-19.
- Carlumab, is a human monoclonal antibody that targets MCP-1 used in the treatment of oncology/immune indications.
- Carotuximab, is a chimeric monoclonal antibody that targets endoglin used in the treatment of angiosarcoma.
- cBR96-doxorubicin immunoconjugate is a humanized monoclonal antibody that targets Lewis-Y antigen used in the treatment of cancer.
- Cedelizumab, is a humanized monoclonal antibody that targets CD4 used in the treatment of prevention of organ transplant rejections, treatment of autoimmune diseases.
- Cergutuzumab amunaleukin, is a humanized monoclonal antibody that targets IL2 used in the treatment of cancer.
- Cetrelimab, is a human monoclonal antibody that targets PD-1 used in the treatment of cancer.
- Cibisatamab, is a humanized monoclonal antibody that targets CEACAM5 used in the treatment of cancer.
- Cirmtuzumab, is a humanizedmonoclonal antibody that targets ROR1 used in the treatment of chronic lymphocytic leukemia.
- Citatuzumab bogatox, is a humanized (Fab), is a EpCAM used in the treatment of ovarian cancer and other solid tumors.
- Cixutumumab, is a human monoclonal antibody that targets IGF-1 receptor (CD221) used in the treatment of solid tumors.
- Clazakizumab, is a humanized monoclonal antibody that targets Interleukin 6 (IL-6) used in the treatment of rheumatoid arthritis.
- Clenoliximab, is a chimeric monoclonal antibody that targets CD4 used in the treatment of rheumatoid arthritis.
- Codrituzumab, is a humanized monoclonal antibody that targets glypican 3 used in the treatment of cancer.
- Cofetuzumab pelidotin, is a humanized monoclonal antibody that targets PTK7 used in the treatment of cancer.
- Coltuximab ravtansine, is a chimeric monoclonal antibody that targets CD19 used in the treatment of cancer.
- Conatumumab, is a human monoclonal antibody that targets TRAIL-R2 used in the treatment of cancer.
- Concizumab, is a humanized monoclonal antibody that targets tissue factor pathway inhibitor (TFPI) used in the treatment of bleeding.
- Crenezumab, is a humanized monoclonal antibody that targets 1-40-β-amyloid used in the treatment of Alzheimer's disease.
- Crotedumab, is a human monoclonal antibody that targets glucagon receptor (GCGR) used in the treatment of diabetes.
- CR6261 is a human monoclonal antibody that targets Influenza A hemagglutinin used in the treatment of infectious disease/influenza A.
- Cusatuzumab, is a humanized monoclonal antibody that targets CD70 used in the treatment of cancer.
- Dacetuzumab, is a humanized monoclonal antibody that targets CD40 used in the treatment of hematologic cancers.
- Dalotuzumab is a humanized monoclonal antibody that targets IGF-1 receptor (CD221) used in the treatment of cancer etc..
- Dapirolizumab pegol, is a humanized monoclonal antibody that targets CD154 (CD40L).
- Dectrekumab, is a human monoclonal antibody that targets IL-13.
- Demcizumab is a humanized monoclonal antibody that targets DLL4 used in the treatment of cancer.
- Denintuzumab mafodotin, is a humanized monoclonal antibody that targets CD19 used in the treatment of cancer.
- Depatuxizumab mafodotin, is a chimeric/humanized monoclonal antibody that targets EGFR used in the treatment of glioblastoma.
- Derlotuximab biotin is a chimeric monoclonal antibody that targets histone complex used in the treatment of recurrent glioblastoma multiforme.
- Detumomab is a mouse monoclonal antibody that targets B-lymphoma cell used in the treatment of lymphoma.
- Dezamizumab, is a humanized monoclonal antibody that targets serum amyloid P component.
- Diridavumab is a human monoclonal antibody that targets hemagglutinin used in the treatment of influenza A.
- Domagrozumab, is a humanized monoclonal antibody that targets GDF-8 used in the treatment of Duchenne muscular dystrophy.
- Dorlimomab aritox, is a mouse (F(ab')2), is a ?.
- Dostarlimab, is a humanized monoclonal antibody that targets PCDP1 used in the treatment of cancer.
- Drozitumab is a human monoclonal antibody that targets DR5 used in the treatment of cancer etc..
- DS-8201 is a humanizedmonoclonal antibody that targets HER2 used in the treatment of gastric or gastroesophageal junction adenocarcinoma.
- Duligotuzumab, is a humanized monoclonal antibody that targets ERBB3 (HER3) used in the treatment of testicular cancer.
- Dusigitumab is a human monoclonal antibody that targets ILGF2 used in the treatment of B-cell malignancies.
- Duvortuxizumab, is a chimeric/humanized (scFv), is a CD19, CD3E used in the treatment of cancer.
- Ecromeximab, is a chimeric monoclonal antibody that targets GD3 ganglioside used in the treatment of malignant melanoma.
- Edobacomab is a mouse monoclonal antibody that targets endotoxin used in the treatment of sepsis caused by Gram-negative bacteria.
- Eldelumab, is a human monoclonal antibody that targets interferon gamma-induced protein used in the treatment of Crohn's disease, ulcerative colitis.
- Elezanumab, is a human monoclonal antibody that targets repulsive guidance molecule A (RGMA) used in the treatment of spinal cord injury and multiple sclerosis.
- Elgemtumab, is a human monoclonal antibody that targets ERBB3 (HER3) used in the treatment of cancer.
- Elsilimomab is a mouse monoclonal antibody that targets IL-6.
- Emactuzumab, is a humanized monoclonal antibody that targets CSF1R used in the treatment of cancer.
- Emibetuzumab is a humanized monoclonal antibody that targets hHGFR used in the treatment of cancer.
- Enapotamab vedotin, is a human monoclonal antibody that targets AXL used in the treatment of cancer.
- Enavatuzumab is a humanized monoclonal antibody that targets TWEAK receptor used in the treatment of cancer etc..
- Enlimomab pegol, is a mouse monoclonal antibody that targets ICAM-1 (CD54).
- Enoblituzumab, is a humanized monoclonal antibody that targets CD276 used in the treatment of cancer.
- Enokizumab is a humanized monoclonal antibody that targets IL9 used in the treatment of asthma.
- Enoticumab, is a human monoclonal antibody that targets DLL4.
- Ensituximab is a chimeric monoclonal antibody that targets MUC5AC used in the treatment of cancer.
- Epcoritamab is a human (bsmonoclonal antibody that targets CD3, CD20 used in the treatment of B-cell lymphoma.
- Epitumomab cituxetan, is a mouse monoclonal antibody that targets episialin.
- Epratuzumab is a humanized monoclonal antibody that targets CD22 used in the treatment of cancer, systemic lupus erythematosus (SLE).
- Erlizumab, is a humanized (F(ab')2), is a ITGB2 (CD18) used in the treatment of heart attack, stroke, traumatic shock.
- Etigilimab, is a humanized monoclonal antibody that targets TIGIT.
- Etrolizumab, is a humanized monoclonal antibody that targets integrin β7 used in the treatment of inflammatory bowel disease.
- Evinacumab is a human monoclonal antibody that targets angiopoietin 3 used in the treatment of dyslipidemia.
- Exbivirumab, is a human monoclonal antibody that targets hepatitis B surface antigen used in the treatment of hepatitis B.
- Faralimomab is a mouse monoclonal antibody that targets interferon receptor.
- Faricimab, is a humanized monoclonal antibody that targets VEGF-A and Ang-2 used in the treatment of angiogenesis, ocular vascular diseases.
- Farletuzumab is a humanized monoclonal antibody that targets folate receptor 1 used in the treatment of ovarian cancer.
- Fasinumab is a human monoclonal antibody that targets Nerve growth factor (HNGF) used in the treatment of acute sciatic pain.
- Felvizumab is a humanized monoclonal antibody that targets respiratory syncytial virus used in the treatment of respiratory syncytial virus infection.
- Fezakinumab, is a human monoclonal antibody that targets IL-22 used in the treatment of rheumatoid arthritis, psoriasis.
- Fibatuzumab, is a humanized monoclonal antibody that targets ephrin receptor A3.
- Ficlatuzumab is a humanized monoclonal antibody that targets Hepatocyte growth factor (HGF) used in the treatment of cancer etc..
- Figitumumab is a human monoclonal antibody that targets IGF-1 receptor (CD221) used in the treatment of adrenocortical carcinoma, non-small cell lung carcinoma etc..
- Firivumab, is a human monoclonal antibody that targets influenza A virus hemagglutinin.
- Flanvotumab is a human monoclonal antibody that targets TYRP1 (glycoprotein 75) used in the treatment of melanoma.
- Fletikumab is a human monoclonal antibody that targets IL 20 used in the treatment of rheumatoid arthritis.
- Flotetuzumab, is a humanized (di-scFv), is a IL 3 receptor used in the treatment of hematological malignancies.
- Foralumab, is a human monoclonal antibody that targets CD3 epsilon.
- Foravirumab, is a human monoclonal antibody that targets rabies virus glycoprotein used in the treatment of rabies (prophylaxis).
- Fresolimumab, is a human monoclonal antibody that targets TGF-β used in the treatment of idiopathic pulmonary fibrosis, focal segmental glomerulosclerosis, cancer.
- Frovocimab, is a humanized monoclonal antibody that targets PCSK9 used in the treatment of hypercholesterolemia.
- Frunevetmab, is a veterinary monoclonal antibody that targets nerve growth factor (NGF).
- Fulranumab is a human monoclonal antibody that targets Nerve growth factor (NGF) used in the treatment of pain.
- Futuximab, is a chimeric monoclonal antibody that targets Epidermal growth factor receptor (EGFR) used in the treatment of cancer.
- Galiximab is a chimeric monoclonal antibody that targets CD80 used in the treatment of B-cell lymphoma.
- Gancotamab is a human (scFv), is a HER2/neu used in the treatment of cancer.
- Ganitumab is a human monoclonal antibody that targets IGF-1 receptor (CD221) used in the treatment of cancer.
- Gantenerumab, is a human monoclonal antibody that targets beta amyloid used in the treatment of Alzheimer's disease.
- Gatipotuzumab, is a humanized monoclonal antibody that targets MUC1 used in the treatment of cancer.
- Gavilimomab, is a mouse monoclonal antibody that targets CD147 (basigin) used in the treatment of graft versus host disease.
- Gedivumab, is a human monoclonal antibody that targets hemagglutinin HA.
- Gevokizumab is a humanized monoclonal antibody that targets IL-1β used in the treatment of diabetes etc..
- Gilvetmab, is a veterinary monoclonal antibody that targets PCDC1.
- Gimsilumab, is a human monoclonal antibody that targets CSF2 used in the treatment of rheumatoid arthritis.
- Glembatumumab vedotin, is a human monoclonal antibody that targets GPNMB used in the treatment of melanoma, breast cancer.
- Gomiliximab is a chimeric monoclonal antibody that targets CD23 (IgE receptor) used in the treatment of allergic asthma.
- Gosuranemab is a humanized monoclonal antibody that targets tau protein used in the treatment of progressive supranuclear palsy.
- Ianalumab, is a human monoclonal antibody that targets BAFF-R used in the treatment of autoimmune hepatitis.
- IBI308 is a humanmonoclonal antibody that targets PD-1 used in the treatment of squamous cell non-small cell lung cancer.
- Icrucumab is a human monoclonal antibody that targets VEGFR-1 used in the treatment of cancer etc..
- Ifabotuzumab, is a humanized monoclonal antibody that targets EPHA3 used in the treatment of glioblastoma multiforme.
- Iladatuzumab vedotin, is a humanized monoclonal antibody that targets CD79B used in the treatment of cancer.
- IMAB362 is a human monoclonal antibody that targets CLDN18.2 used in the treatment of gastrointestinal adenocarcinomas and pancreatic tumor.
- Imalumab, is a human monoclonal antibody that targets macrophage migration inhibitory factor (MIF) used in the treatment of cancer.
- Imaprelimab, is a humanized monoclonal antibody that targets melanoma cell adhesion molecule (MCAM).
- Imdevimab is a human monoclonal antibody that targets spike protein receptor binding domain (RBD) of SARS-CoV-2 used in the treatment of COVID-19.
- Imgatuzumab, is a humanized monoclonal antibody that targets Epidermal growth factor receptor (EGFR) used in the treatment of cancer.
- Inclacumab, is a human monoclonal antibody that targets selectin P used in the treatment of cardiovascular disease.
- Indatuximab ravtansine, is a chimeric monoclonal antibody that targets SDC1 used in the treatment of cancer.
- Indusatumab vedotin, is a human monoclonal antibody that targets GUCY2C used in the treatment of cancer.
- Intetumumab5, is a human monoclonal antibody that targets CD51 used in the treatment of solid tumors (prostate cancer, melanoma).
- Inolimomab is a mouse monoclonal antibody that targets CD25 (α chain of IL-2 receptor) used in the treatment of graft versus host disease.
- Iomab-B is a mousemonoclonal antibody that targets CD45 used in the treatment of ablation of bone marrow.
- Iratumumab, is a human monoclonal antibody that targets CD30 (TNFRSF8) used in the treatment of Hodgkin's lymphoma.
- Iscalimab, is a human monoclonal antibody that targets CD40.
- Istiratumab, is a human monoclonal antibody that targets IGF1R, CD221 used in the treatment of advanced solid tumors.
- Keliximab is a chimeric monoclonal antibody that targets CD4 used in the treatment of chronic asthma.
- Lacnotuzumab, is a humanized monoclonal antibody that targets CSF1, macrophage colony stimulating factor (MCSF) used in the treatment of cancer.
- Ladiratuzumab vedotin, is a humanized monoclonal antibody that targets LIV-1 used in the treatment of cancer.
- Lampalizumab, is a humanized (Fab), is a Complement factor D (CFD) used in the treatment of geographic atrophy secondary to age-related macular degeneration.
- Landogrozumab, is a humanized monoclonal antibody that targets GDF-8 used in the treatment of muscle wasting disorders.
- Laprituximab emtansine, is a chimeric monoclonal antibody that targets epidermal growth factor receptor (EGFR).
- Larcaviximab, is a chimeric monoclonal antibody that targets ebolavirus glycoprotein used in the treatment of Ebola virus.
- Lebrikizumab is a humanized monoclonal antibody that targets IL-13 used in the treatment of asthma.
- Lemalesomab, is a mouse monoclonal antibody that targets NCA-90 (granulocyte antigen) used in the treatment of diagnostic agent.
- Lendalizumab, is a humanized monoclonal antibody that targets C5.
- Lenvervimab, is a humanized monoclonal antibody that targets hepatitis B surfage antigen used in the treatment of hepatitis B.
- Lenzilumab, is a human monoclonal antibody that targets CSF2 used in the treatment of chronic myelomonocytic leukemia and juvenile myelomonocytic leukemia.
- Lerdelimumab, is a human monoclonal antibody that targets TGF beta 2 used in the treatment of reduction of scarring after glaucoma surgery.
- Leronlimab, is a humanized monoclonal antibody that targets CCR5 used in the treatment of breast cancer, HIV.
- Lesofavumab, is a human monoclonal antibody that targets hemagglutinin HA.
- Letolizumab, is a humanized (scFv), is a tumor necrosis factor related activation protein (TRAP) used in the treatment of inflammatory diseases.
- Lexatumumab, is a human monoclonal antibody that targets TRAIL-R2 used in the treatment of cancer.
- Libivirumab, is a human monoclonal antibody that targets hepatitis B surface antigen used in the treatment of hepatitis B.
- Lifastuzumab vedotin is a humanized monoclonal antibody that targets phosphate-sodium co-transporter used in the treatment of cancer.
- Ligelizumab, is a humanized monoclonal antibody that targets IGHE used in the treatment of severe asthma and chronic spontaneous urticaria.
- Loncastuximab tesirine, is a chimeric monoclonal antibody that targets CD19 used in the treatment of cancer.
- Losatuxizumab vedotin, is a chimeric/humanized monoclonal antibody that targets epidermal growth receptor factor (EGRF), ERBB1 HER1 used in the treatment of cancer.
- Lilotomab satetraxetan, is a mouse monoclonal antibody that targets CD37 used in the treatment of cancer.
- Lintuzumab is a humanized monoclonal antibody that targets CD33 used in the treatment of cancer.
- Lirilumab, is a human monoclonal antibody that targets KIR2D used in the treatment of solid and hematological cancers.
- Lodelcizumab, is a humanized monoclonal antibody that targets PCSK9 used in the treatment of hypercholesterolemia.
- Lorvotuzumab mertansine is a humanized monoclonal antibody that targets CD56 used in the treatment of cancer.
- Lucatumumab, is a human monoclonal antibody that targets CD40 used in the treatment of multiple myeloma, non-Hodgkin's lymphoma, Hodgkin's lymphoma.
- Lulizumab pegol, is a humanized monoclonal antibody that targets CD28 used in the treatment of autoimmune diseases.
- Lumiliximab, is a chimeric monoclonal antibody that targets CD23 (IgE receptor) used in the treatment of chronic lymphocytic leukemia.
- Lumretuzumab, is a humanized monoclonal antibody that targets ERBB3 (HER3) used in the treatment of cancer.
- Lupartumab, is a human (mab), is a ?.
- Lupartumab amadotin, is a human monoclonal antibody that targets LYPD3.
- Lutikizumab, is a humanized monoclonal antibody that targets interleukin 1 alpha.
- Maftivimab is a human (mab), is a part of Atoltivimab/maftivimab/odesivimab for treatment of Zaire ebolavirus (Ebola virus).
- Mapatumumab, is a human monoclonal antibody that targets TRAIL-R1 used in the treatment of cancer.
- Marstacimab is a human monoclonal antibody that targets tissue factor pathway inhibitor (TFPI) used in the treatment of bleeding with hemophilia.
- Maslimomab is a mousemonoclonal antibody that targets T-cell receptor.
- Mavrilimumab, is a human monoclonal antibody that targets GMCSF receptor α-chain used in the treatment of rheumatoid arthritis.
- Matuzumab, is a humanized monoclonal antibody that targets Epidermal growth factor receptor (EGFR) used in the treatment of colorectal, lung and stomach cancer.
- Metelimumab, is a human monoclonal antibody that targets TGF beta 1 used in the treatment of systemic scleroderma.
- Milatuzumab, is a humanized monoclonal antibody that targets CD74 used in the treatment of multiple myeloma and other hematological malignancies.
- Minretumomab is a mouse monoclonal antibody that targets TAG-72 used in the treatment of tumor detection (and therapy?).
- Mirikizumab, is a humanized monoclonal antibody that targets IL23A used in the treatment of psoriasis.
- Mirvetuximab soravtansine is a chimeric monoclonal antibody that targets folate receptor alpha used in the treatment of ovarian cancer.
- Mitumomab is a mouse monoclonal antibody that targets GD3 ganglioside used in the treatment of small cell lung carcinoma.
- Modotuximab is a chimeric monoclonal antibody that targets EGFR extracellular domain III used in the treatment of cancer.
- Monalizumab, is a humanized monoclonal antibody that targets NKG2A used in the treatment of rheumatoid arthritis, gynecologic malignancies, and other cancers.
- Morolimumab, is a human monoclonal antibody that targets Rhesus factor.
- Mosunetuzumab, is a humanized monoclonal antibody that targets CD3E, MS4A1, CD20 used in the treatment of cancer.
- Nacolomab tafenatox is a mouse (Fab), is a C242 antigen used in the treatment of colorectal cancer.
- Namilumab, is a human monoclonal antibody that targets CSF2.
- Naptumomab estafenatox, is a mouse (Fab), is a 5T4 used in the treatment of non-small cell lung carcinoma, renal cell carcinoma.
- Naratuximab emtansine, is a chimeric monoclonal antibody that targets CD37.
- Narnatumab is a human monoclonal antibody that targets MST1R (aka RON) used in the treatment of cancer.
- Navicixizumab, is a chimeric/humanized monoclonal antibody that targets DLL4 and VEGFA used in the treatment of cancer.
- Navivumab, is a human monoclonal antibody that targets influenza A virus hemagglutinin HA.
- Nebacumab is a human monoclonal antibody that targets endotoxin used in the treatment of sepsis.
- Nemolizumab, is a humanized monoclonal antibody that targets IL31RA used in the treatment of eczema.
- NEOD001 is a humanizedmonoclonal antibody that targets amyloid used in the treatment of primary systemic amyloidosis.
- Nerelimomab is a mouse monoclonal antibody that targets TNF-α.
- Nesvacumab is a human monoclonal antibody that targets angiopoietin 2 used in the treatment of cancer.
- Nirsevimab is a human monoclonal antibody that targets RSV fusion glycoprotein used in the treatment of respiratory syncytial virus.
- Ocaratuzumab is a humanized monoclonal antibody that targets CD20 used in the treatment of cancer.
- Odesivimab is a human (mab), is a part of Atoltivimab/maftivimab/odesivimab for treatment of Zaire ebolavirus (Ebola virus).
- Odulimomab is a mouse monoclonal antibody that targets LFA-1 (CD11a) used in the treatment of prevention of organ transplant rejections, immunological diseases.
- Oleclumab, is a human monoclonal antibody that targets 5'-nucleotidase used in the treatment of pancreatic and colorectal cancer.
- Olendalizumab, is a humanized monoclonal antibody that targets complement C5a used in the treatment of systemic lupus erythematosus, lupus nephritis, acute graft-versus-hose disease.
- Olokizumab, is a humanized monoclonal antibody that targets IL6 used in the treatment of rheumatoid arthritis.
- Omburtamab, is a mouse monoclonal antibody that targets CD276 used in the treatment of cancer.
- OMS721 is a humanmonoclonal antibody that targets MASP-2 used in the treatment of atypical hemolytic uremic syndrome.
- Onartuzumab is a humanized (Fab), is a human scatter factor receptor kinase used in the treatment of cancer.
- Ontuxizumab is a chimeric/humanized monoclonal antibody that targets TEM1 used in the treatment of cancer.
- Onvatilimab, is a human monoclonal antibody that targets VISTA (protein) (VSIR).
- Opicinumab is a human monoclonal antibody that targets LINGO-1 used in the treatment of multiple sclerosis.
- Orticumab, is a human monoclonal antibody that targets oxLDL.
- Otelixizumab, is a chimeric/humanized monoclonal antibody that targets CD3 used in the treatment of diabetes mellitus type 1.
- Otilimab is a human monoclonal antibody that targets GMCSF used in the treatment of osteoarthritis, rheumatoid arthritis.
- Otlertuzumab is a humanized monoclonal antibody that targets CD37 used in the treatment of cancer.
- Oxelumab, is a human monoclonal antibody that targets OX-40 used in the treatment of asthma.
- Ozanezumab is a humanized monoclonal antibody that targets NOGO-A used in the treatment of ALS and multiple sclerosis.
- Ozoralizumab, is a humanized monoclonal antibody that targets TNF-α used in the treatment of inflammation.
- Pagibaximab, is a chimeric monoclonal antibody that targets lipoteichoic acid used in the treatment of sepsis (Staphylococcus).
- Pamrevlumab, is a human monoclonal antibody that targets connective tissue growth factor (CTGF) used in the treatment of idiopathic pulmonary fibrosis (IPF), pancreatic cancer.
- Pankomab is a humanized monoclonal antibody that targets tumor specific glycosylation of MUC1 used in the treatment of ovarian cancer.
- Panobacumab, is a human monoclonal antibody that targets Pseudomonas aeruginosa used in the treatment of Pseudomonas aeruginosa infection.
- Parsatuzumab, is a humanized monoclonal antibody that targets EGFL7 used in the treatment of cancer.
- Pascolizumab, is a humanized monoclonal antibody that targets IL-4 used in the treatment of asthma.
- Pasotuxizumab, is a chimeric/humanized monoclonal antibody that targets folate hydrolase used in the treatment of cancer.
- Pateclizumab, is a humanized monoclonal antibody that targets lymphotoxin alpha (LTA) used in the treatment of TNF.
- Patritumab, is a human monoclonal antibody that targets ERBB3 (HER3) used in the treatment of cancer.
- PDR001 is a humanizedmonoclonal antibody that targets PD-1 used in the treatment of melanoma.
- Perakizumab, is a humanized monoclonal antibody that targets IL 17A used in the treatment of arthritis.
- Pexelizumab, is a humanized (scFv), is a C5 used in the treatment of reduction of side effects of cardiac surgery.
- Pidilizumab, is a humanized monoclonal antibody that targets PD-1 used in the treatment of cancer and infectious diseases.
- Pinatuzumab vedotin, is a humanized monoclonal antibody that targets CD22 used in the treatment of cancer.
- Pintumomab is a mouse monoclonal antibody that targets adenocarcinoma antigen used in the treatment of adenocarcinoma (imaging).
- Placulumab, is a human monoclonal antibody that targets human TNF used in the treatment of pain and inflammatory diseases.
- Prezalumab, is a human monoclonal antibody that targets human TNF.
- Plozalizumab, is a humanized monoclonal antibody that targets CCR2 used in the treatment of diabetic nephropathy and arteriovenous graft patency.
- Pogalizumab, is a humanized monoclonal antibody that targets tumor necrosis factor receptor (TNFR) superfamily member 4.
- Ponezumab is a humanized monoclonal antibody that targets human beta-amyloid used in the treatment of Alzheimer's disease.
- Porgaviximab, is a chimeric monoclonal antibody that targets Zaire ebolavirus glycoprotein used in the treatment of Ebola virus disease.
- Prasinezumab, is a humanized monoclonal antibody that targets sodium cyclopentadienide (NACP) used in the treatment of Parkinson's disease.
- Prezalizumab, is a humanized monoclonal antibody that targets inducible T-cell co-stimulatory ligand (ICOSL).
- Priliximab is a chimeric monoclonal antibody that targets CD4 used in the treatment of Crohn's disease, multiple sclerosis.
- Pritoxaximab, is a chimeric monoclonal antibody that targets E. coli shiga toxin type-1.
- Pritumumab is a human monoclonal antibody that targets vimentin used in the treatment of brain cancer.
- PRO 140 is a humanizedmonoclonal antibody that targets CCR5 used in the treatment of HIV infection.
- Quilizumab, is a humanized monoclonal antibody that targets IGHE used in the treatment of asthma.
- Radretumab, is a human monoclonal antibody that targets fibronectin extra domain-B used in the treatment of cancer.
- Rafivirumab, is a human monoclonal antibody that targets rabies virus glycoprotein used in the treatment of rabies (prophylaxis).
- Ralpancizumab is a humanized monoclonal antibody that targets PCSK9 used in the treatment of dyslipidemia.
- Ranevetmab is a veterinary monoclonal antibody that targets NGF used in the treatment of osteoarthritis in dogs.
- Raxibacumab, is a human monoclonal antibody that targets anthrax toxin, protective antigen used in the treatment of anthrax (prophylaxis and treatment).
- Ravagalimab, is a humanized monoclonal antibody that targets CD40 used in the treatment of Crohn's disease.
- Refanezumab is a humanized monoclonal antibody that targets myelin-associated glycoprotein used in the treatment of recovery of motor function after stroke.
- Regavirumab is a human monoclonal antibody that targets cytomegalovirus glycoprotein B used in the treatment of cytomegalovirus infection.
- REGN-EB3 is a human (mab), is a 3 mabs for ebola infection with FDA orphan drug status.
- Relatlimab is a human monoclonal antibody that targets LAG3 used in the treatment of melanoma.
- Remtolumab, is a human monoclonal antibody that targets interleukin 17 alpha, TNF.
- Rilotumumab is a human monoclonal antibody that targets hepatocyte growth factor (HGF) used in the treatment of solid tumors.
- Rinucumab is a human monoclonal antibody that targets platelet-derived growth factor receptor beta used in the treatment of neovascular age-related macular degeneration.
- Rivabazumab pegol, is a humanized monoclonal antibody that targets Pseudomonas aeruginosa type III secretion system.
- Robatumumab is a human monoclonal antibody that targets IGF-1 receptor (CD221) used in the treatment of cancer.
- Roledumab, is a human monoclonal antibody that targets RHD (gene) (RHD) used in the treatment of Rh disease.
- Romilkimab, is a chimeric/humanized monoclonal antibody that targets interleukin 13.
- Rontalizumab, is a humanized monoclonal antibody that targets IFN-α used in the treatment of systemic lupus erythematosus.
- Rosmantuzumab, is a humanized monoclonal antibody that targets root plate-specific spondin 3 used in the treatment of cancer.
- Rovalpituzumab tesirine, is a humanized monoclonal antibody that targets DLL3 used in the treatment of small cell lung cancer.
- Rozanolixizumab, is a chimeric/humanized monoclonal antibody that targets FCGRT used in the treatment of Immune thrombocytopenic purpura (ITP), myasthenia gravis.
- SA237 is a humanizedmonoclonal antibody that targets IL-6R used in the treatment of neuromyelitis optica and neuromyelitis optica spectrum disorders.
- Samalizumab, is a humanized monoclonal antibody that targets CD200 used in the treatment of cancer.
- Samrotamab vedotin, is a chimeric/humanized monoclonal antibody that targets LRRC15 used in the treatment of cancer.
- Satumomab pendetide is a mouse monoclonal antibody that targets TAG-72 used in the treatment of cancer (diagnosis).
- Selicrelumab, is a human monoclonal antibody that targets CD40.
- Seribantumab, is a human monoclonal antibody that targets ERBB3 (HER3) used in the treatment of cancer.
- Setoxaximab, is a chimeric monoclonal antibody that targets E. coli shiga toxin type-2.
- Setrusumab, is a human monoclonal antibody that targets sclerostin (SOST).
- Sevirumab is a humanmonoclonal antibody that targets cytomegalovirus used in the treatment of cytomegalovirus infection.
- Sibrotuzumab is a humanized monoclonal antibody that targets FAP (gene) (FAP) used in the treatment of cancer.
- SGN-CD19A is a humanized monoclonal antibody that targets CD19 used in the treatment of acute lymphoblastic leukemia and B-cell non-Hodgkin lymphoma.
- SHP647 is a humanmonoclonal antibody that targets mucosal addressin cell adhesion molecule used in the treatment of Crohn's disease.
- Sifalimumab, is a human monoclonal antibody that targets IFN-α used in the treatment of systemic lupus erythematosus (SLE), dermatomyositis, polymyositis.
- Simtuzumab, is a humanized monoclonal antibody that targets LOXL2 used in the treatment of fibrosis.
- Siplizumab, is a humanized monoclonal antibody that targets CD2 used in the treatment of psoriasis, graft-versus-host disease (prevention).
- Sirtratumab vedotin, is a human monoclonal antibody that targets SLITRK6 used in the treatment of cancer.
- Sirukumab is a human monoclonal antibody that targets IL-6 used in the treatment of rheumatoid arthritis.
- Sofituzumab vedotin is a humanized monoclonal antibody that targets CA-125 used in the treatment of ovarian cancer.
- Solanezumab, is a humanized monoclonal antibody that targets beta amyloid used in the treatment of Alzheimer's disease.
- Solitomab, is a mouse (BiTE), is a EpCAM used in the treatment of gastrointestinal, lung, and other cancers.
- Sonepcizumab, is a humanizedmonoclonal antibody that targets sphingosine-1-phosphate used in the treatment of choroidal and retinal neovascularization.
- Sontuzumab, is a humanized monoclonal antibody that targets episialin.
- Spartalizumab, is a humanized monoclonal antibody that targets PDCD1, CD279 used in the treatment of melanoma.
- Stamulumab, is a human monoclonal antibody that targets myostatin used in the treatment of muscular dystrophy.
- Suptavumab, is a human monoclonal antibody that targets RSVFR used in the treatment of medically attended lower respiratory disease.
- Sutimlimab, is a chimeric/humanized monoclonal antibody that targets C1s used in the treatment of cold agglutinin disease.
- Suvizumab, is a humanized monoclonal antibody that targets HIV-1 used in the treatment of viral infections.
- Suvratoxumab, is a human monoclonal antibody that targets Staphylococcus aureus alpha toxin used in the treatment of nosocomial pneumonia.
- Tabalumab, is a human monoclonal antibody that targets B-cell activating factor (BAFF) used in the treatment of B-cell cancers.
- Tadocizumab, is a humanized (Fab), is a integrin αIIbβ3 used in the treatment of percutaneous coronary intervention.
- Talacotuzumab, is a humanized monoclonal antibody that targets CD123 used in the treatment of leukemia etc..
- Talizumab, is a humanized monoclonal antibody that targets IgE used in the treatment of allergic reaction.
- Talquetamab is a human (bsmonoclonal antibody that targets GPRC5D, CD3 used in the treatment of relapsed or refractory multiple myeloma.
- Tanezumab, is a humanized monoclonal antibody that targets nerve growth factor (NGF) used in the treatment of pain.
- Taplitumomab paptox, is a mouse monoclonal antibody that targets CD19 used in the treatment of cancer(citation needed).
- Tarextumab is a human monoclonal antibody that targets Notch receptor used in the treatment of cancer.
- Tavolimab is a chimeric/humanized monoclonal antibody that targets CD134 used in the treatment of cancer.
- Teclistamab is a human (bsmonoclonal antibody that targets B-cell maturation antigen (BCMA), CD3 used in the treatment of relapsed or refractory multiple myeloma.
- Telimomab aritox is a mouse (Fab), is a ?.
- Telisotuzumab, is a humanized monoclonal antibody that targets HGFR used in the treatment of cancer.
- Telisotuzumab vedotin, is a humanized monoclonal antibody that targets HGFR used in the treatment of cancer.
- Tenatumomab, is a mouse monoclonal antibody that targets tenascin C used in the treatment of cancer.
- Teneliximab, is a chimeric monoclonal antibody that targets CD40 used in the treatment of autoimmune diseases and prevention of organ transplant rejection.
- Teplizumab, is a humanized monoclonal antibody that targets CD3 used in the treatment of diabetes mellitus type 1.
- Tepoditamab, is a human monoclonal antibody that targets dendritic cell-associated lectin 2 used in the treatment of cancer.
- Tesidolumab, is a human monoclonal antibody that targets C5.
- Tetulomab is a humanized monoclonal antibody that targets CD37 used in the treatment of cancer.
- Tezepelumab, is a human monoclonal antibody that targets thymic stromal lymphopoietin (TSLP) used in the treatment of asthma, atopic dermatitis.
- TGN1412 is a humanizedmonoclonal antibody that targets CD28 used in the treatment of chronic lymphocytic leukemia, rheumatoid arthritis.
- Tibulizumab, is a humanized monoclonal antibody that targets B-cell activating factor (BAFF) used in the treatment of autoimmune disorders.
- Tigatuzumab, is a humanized monoclonal antibody that targets TRAIL-R2 used in the treatment of cancer.
- Timigutuzumab, is a humanized monoclonal antibody that targets HER2 used in the treatment of cancer.
- Timolumab, is a human monoclonal antibody that targets AOC3.
- tiragolumab, is a human (mab), is a .
- Tiragotumab, is a human monoclonal antibody that targets TIGIT used in the treatment of cancer.
- Tislelizumab, is a humanized monoclonal antibody that targets PCDC1, CD279 used in the treatment of non-small cell lung cancer.
- Tisotumab vedotin, is a human monoclonal antibody that targets coagulation factor III used in the treatment of relapsed or refractory cervical cancer.
- TNX-650 is a humanizedmonoclonal antibody that targets IL-13 used in the treatment of Hodgkin's lymphoma.
- Tomuzotuximab, is a humanized monoclonal antibody that targets epidermal growth factor receptor (EGFR), HER1 used in the treatment of cancer.
- Toralizumab, is a humanized monoclonal antibody that targets CD154 (CD40L) used in the treatment of rheumatoid arthritis, lupus nephritis etc..
- Tosatoxumab, is a human monoclonal antibody that targets Staphylococcus aureus.
- Tovetumab is a human monoclonal antibody that targets PDGFRA used in the treatment of cancer.
- Tralokinumab is a human monoclonal antibody that targets IL-13 used in the treatment of asthma, atopic dermatitis.
- Tregalizumab, is a humanized monoclonal antibody that targets CD4.
- Tremelimumab, is a human monoclonal antibody that targets CTLA-4 used in the treatment of non-small cell lung, head & neck, urothelial cancer.
- Trevogrumab is a human monoclonal antibody that targets growth differentiation factor 8 used in the treatment of muscle atrophy due to orthopedic disuse and sarcopenia.
- Tucotuzumab celmoleukin, is a humanized monoclonal antibody that targets EpCAM used in the treatment of cancer.
- Tuvirumab is a humanmonoclonal antibody that targets hepatitis B virus used in the treatment of chronic hepatitis B.
- Ublituximab, is a chimeric monoclonal antibody that targets MS4A1 used in the treatment of multiple sclerosis, chronic lymphocytic leukemia.
- Ulocuplumab, is a human monoclonal antibody that targets CXCR4 (CD184) used in the treatment of hematologic malignancies.
- Urelumab, is a human monoclonal antibody that targets 4-1BB (CD137) used in the treatment of cancer etc..
- Urtoxazumab, is a humanized monoclonal antibody that targets Escherichia coli used in the treatment of diarrhoea caused by E. coli.
- Utomilumab, is a human monoclonal antibody that targets 4-1BB (CD137) used in the treatment of diffuse large B-cell lymphoma.
- Vadastuximab talirine, is a chimeric monoclonal antibody that targets CD33 used in the treatment of Acute myeloid leukemia.
- Vanalimab, is a humanized monoclonal antibody that targets CD40.
- Vandortuzumab vedotin, is a humanized monoclonal antibody that targets STEAP1 used in the treatment of cancer.
- Vantictumab is a human monoclonal antibody that targets Frizzled receptor used in the treatment of cancer.
- Vanucizumab, is a humanized monoclonal antibody that targets angiopoietin 2 used in the treatment of cancer.
- Vapaliximab, is a chimeric monoclonal antibody that targets AOC3 (VAP-1).
- Varisacumab, is a human monoclonal antibody that targets VEGF-A used in the treatment of angiogenesis.
- Varlilumab, is a human monoclonal antibody that targets CD27 used in the treatment of solid tumors and hematologic malignancies.
- Vatelizumab, is a humanized monoclonal antibody that targets ITGA2 (CD49b).
- Veltuzumab, is a humanized monoclonal antibody that targets CD20 used in the treatment of non-Hodgkin's lymphoma.
- Vepalimomab is a mouse monoclonal antibody that targets AOC3 (VAP-1) used in the treatment of inflammation.
- Vesencumab, is a human monoclonal antibody that targets NRP1 used in the treatment of solid malignancies.
- Vobarilizumab, is a humanized (scFv), is a IL6R used in the treatment of inflammatory autoimmune diseases.
- Volociximab, is a chimeric monoclonal antibody that targets integrin α5β1 used in the treatment of solid tumors.
- Vonlerolizumab, is a humanized monoclonal antibody that targets CD134 used in the treatment of cancer.
- Vopratelimab, is a humanized monoclonal antibody that targets CD278, aka ICOS.
- Vorsetuzumab mafodotin is a humanized monoclonal antibody that targets CD70 used in the treatment of cancer.
- Vunakizumab, is a humanized monoclonal antibody that targets interleukin 17 alpha.
- Xentuzumab, is a humanized monoclonal antibody that targets IGF1, IGF2.
- XMAB-5574 is a humanizedmonoclonal antibody that targets CD19 used in the treatment of diffuse large B-cell lymphoma.
- Zalutumumab, is a human monoclonal antibody that targets Epidermal growth factor receptor (EGFR) used in the treatment of squamous cell carcinoma of the head and neck.
- Zanolimumab, is a human monoclonal antibody that targets CD4 used in the treatment of rheumatoid arthritis, psoriasis, T-cell lymphoma.
- Zatuximab, is a chimeric monoclonal antibody that targets HER1 used in the treatment of cancer.
- Zenocutuzumab, is a humanized monoclonal antibody that targets ERBB3, HER3 used in the treatment of cancer.
- Ziralimumab is a human monoclonal antibody that targets CD147 (basigin).
- Zolbetuximab, tradename IMAB362, Claudiximab, is a chimeric monoclonal antibody that targets Claudin 18 Isoform 2 used in the treatment of gastric cancer, gastrointestinal adenocarcinoma and pancreatic cancer.
- Zolimomab aritox is a mouse monoclonal antibody that targets CD5 used in the treatment of systemic lupus erythematosus, graft-versus-host disease.
Monoclonal antibodies Resources | ||
---|---|---|
|
|
Translate to: East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski
Navigation: Wellness - Encyclopedia - Health topics - Disease Index - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro) available.
Advertise on WikiMD
WikiMD is not a substitute for professional medical advice. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD