Rontalizumab
Rontalizumab is a humanized monoclonal antibody designed for the treatment of rheumatoid arthritis. It was developed by Genentech, a member of the Roche Group. Rontalizumab targets and inhibits the interferon alpha (IFN-α), a protein that plays a key role in the inflammatory process of rheumatoid arthritis.
Development and Clinical Trials[edit | edit source]
Rontalizumab was developed by Genentech, a biotechnology company that specializes in the research and development of medicines for serious diseases. The drug was designed to target and inhibit the activity of IFN-α, a protein that is involved in the inflammatory process of rheumatoid arthritis.
In clinical trials, rontalizumab was found to be well-tolerated and showed potential efficacy in reducing the signs and symptoms of rheumatoid arthritis. However, the drug did not meet the primary endpoint in a Phase II study, which led to the discontinuation of its development.
Mechanism of Action[edit | edit source]
Rontalizumab works by binding to IFN-α, a protein that plays a crucial role in the inflammatory process of rheumatoid arthritis. By inhibiting the activity of this protein, rontalizumab can potentially reduce the inflammation and pain associated with this condition.
Potential Side Effects[edit | edit source]
As with any medication, rontalizumab may cause side effects. In clinical trials, the most common side effects reported were infections, including upper respiratory tract infections and urinary tract infections. Other potential side effects include injection site reactions, fatigue, and nausea.
See Also[edit | edit source]
| Rontalizumab Resources | |
|---|---|
|
 |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
