Bavituximab

bavituximab (ba-vih-TUK-sih-mab)A substance being studied in the treatment of several types of cancer and infections caused by certain viruses. It binds to substances on the surface of tumor cells, certain viruses, and cells infected with a virus. The immune system detects bavituximab on the cells and the viruses and may destroy them. It is a type of monoclonal antibody and a type of targeted therapy agent. Also called Tarvacin.

Monoclonal antibodies for tumors

Human ("-tumu-")	* Adecatumumab§ Ascrinvacumab§ Cixutumumab§ Conatumumab§ Daratumumab Drozitumab§ Duligotumab§ Dusigitumab§ Enfortumab vedotin† Enoticumab§ Figitumumab§ Ganitumab† Glembatumumab vedotin† Intetumumab§ Ipilimumab Iratumumab§ Istiratumab Icrucumab§ Lexatumumab§ Lucatumumab§ Mapatumumab§ Narnatumab§ Necitumumab Nesvacumab§ Nivolumab Ofatumumab Olaratumab† Panitumumab Patritumab§ Pembrolizumab Pritumumab§ Radretumab§ Ramucirumab Rilotumumab† Robatumumab§ Seribantumab§ Tarextumab§ Teprotumumab† Tovetumab§ Vantictumab§ Votumumab§ Zalutumumab† "-melu-" (melanoma) Flanvotumab§
Mouse ("-tumo-")	ltumomab pentetate Altumomab pentetate Anatumomab mafenatox Arcitumomab Bectumomab Blinatumomab Detumomab Ibritumomab tiuxetan Lilotomab Minretumomab Mitumomab Moxetumomab pasudotox† Naptumomab estafenatox Nofetumomab merpentan Pemtumomab† Pintumomab Racotumomab Satumomab pendetide Solitomab Taplitumomab paptox Tenatumomab Tositumomab 3F8 "-govo-" (ovarian tumor) Abagovomab Igovomab Oregovomab "-pro-" (prostate tumor) Capromab pendetide "-colo-" (colonic tumor) Edrecolomab Nacolomab tafenatox altumomab_pentetate
Chimeric ("-tuxi-")	* Amatuximab§ Bavituximab§ Brentuximab vedotin Carotuximab† Cetuximab Derlotuximab biotin§ Dinutuximab Ensituximab§ Futuximab§ Girentuximab† Indatuximab ravtansine§ Isatuximab† Loncastuximab tesirine Margetuximab† Rituximab# Siltuximab Ublituximab† IMAB362 "-mexi-" (melanoma): Ecromeximab§
Humanized ("-tuzu-")	* Abituzumab§ Alemtuzumab Bevacizumab Bivatuzumab mertansine§ Brontictuzumab§ Cantuzumab mertansine§ Cantuzumab ravtansine§ Cirmtuzumab Citatuzumab bogatox§ Clivatuzumab tetraxetan Cofetuzumab pelidotin Dacetuzumab§ Demcizumab§ Dalotuzumab§ Denintuzumab mafodotin§ Elotuzumab Emactuzumab§ Emibetuzumab§ Enoblituzumab§ Etaracizumab§ Farletuzumab§ Ficlatuzumab§ Flotetuzumab§ Gemtuzumab ozogamicin‡ Imgatuzumab§ Inotuzumab ozogamicin† Labetuzumab§ Lifastuzumab vedotin§ Lintuzumab§ Lorvotuzumab mertansine§ Lumretuzumab§ Matuzumab§ Milatuzumab§ Nimotuzumab† Obinutuzumab Ocaratuzumab§ Otlertuzumab§ Onartuzumab§ Oportuzumab monatox† Parsatuzumab§ Pertuzumab Pinatuzumab vedotin§ Polatuzumab vedotin† Rosmantuzumab Rovalpituzumab tesirine† [[Sacituzumab govitecan† Sibrotuzumab§ Simtuzumab§ Tacatuzumab tetraxetan§ Tigatuzumab§ Trastuzumab Tucotuzumab celmoleukin§ Vandortuzumab vedotin§ Vanucizumab§ Veltuzumab§ Vorsetuzumab mafodotin§ CBR96-doxorubicin immunoconjugate PankoMab "-gozu-" (ovarian tumor) Sofituzumab vedotin§
Rat/mouse hybrid ("-tumaxo-")	* Catumaxomab Ertumaxomab§
Chimeric + humanized ("-tuxizu-")	* Depatuxizumab mafodotin† Duvortuxizumab Ontuxizumab§

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^{†Phase III}
- ^§Never to phase III

Bavituximab Resources
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