Ianalumab

From WikiMD's WELLNESSPEDIA

Ianalumab is a human monoclonal antibody designed for the treatment of diseases that are mediated by the B cell activating factor (BAFF), such as systemic lupus erythematosus and Sjögren's syndrome. It was developed by Novartis.

Mechanism of action[edit]

Ianalumab works by binding to the B cell activating factor (BAFF), a protein that plays a key role in the survival and proliferation of B cells. By blocking BAFF, ianalumab reduces the number of B cells, which are thought to contribute to the development of autoimmune diseases.

Clinical trials[edit]

Ianalumab has been tested in several clinical trials. In a phase II trial for systemic lupus erythematosus, ianalumab showed a significant reduction in disease activity compared to placebo. A phase III trial is currently underway.

Side effects[edit]

The most common side effects of ianalumab include infections, headache, and nausea. Serious side effects can include severe infections and allergic reactions.

See also[edit]

References[edit]



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