Olokizumab
Olokizumab is a humanized monoclonal antibody designed for the treatment of Rheumatoid arthritis. It is developed by R-Pharm and UCB.
Mechanism of Action[edit | edit source]
Olokizumab works by targeting and inhibiting the IL-6 cytokine, a protein that plays an important role in the inflammatory response of the immune system. By blocking the action of IL-6, Olokizumab can reduce inflammation and slow the progression of rheumatoid arthritis.
Clinical Trials[edit | edit source]
Olokizumab has undergone Phase III clinical trials for the treatment of rheumatoid arthritis. The trials have shown that Olokizumab is effective in reducing the symptoms of rheumatoid arthritis and improving the quality of life for patients.
Side Effects[edit | edit source]
Like all medications, Olokizumab can cause side effects. The most common side effects reported in clinical trials include upper respiratory tract infections, nasopharyngitis, and injection site reactions.
Approval[edit | edit source]
Olokizumab has been approved for use in Russia and is currently under review by the EMA and the FDA in the United States.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD
